Gene Information

Name : sipD
Accession : NP_457277.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2878765 - 2879787 bp
Length : 1023 bp
Strand : -
Note : Previously sequenced Salmonella typhi SipD TR:Q56136 (EMBL:X82670) (339 aa) fasta scores: E(): 0, 96.2% id in 340 aa. Also highly similar to Shigella flexneri 36 kDa membrane antigenic protein associated with virulence IpaD SW:IPAD_SHIFL (P18013) (332 aa)

DNA sequence :
ATGCTTAATATTCAAAATTATTCCGCTTCTCCTCATCCGGGGATCGTTGCCGAACGGCCGCAGACTCCTTCGGCGAGCGA
GCACGCCGAGATTGCCGTGGTACCGTCTACCACAGAACATCGCGGCACAGATATCATTTCATTATCGCAGGCGGCTACTA
AAATCCAGCAGGCACAGCAGACGCTGCAGTCAACGCCACCGATTTCTGAAGAGAATAATGACGAGCGCACGCTGGCGCGC
CAACAGTTGACCAGCAGCCTGAATGCGCTGGCGAAGTCCGGCGTGTCATTATCCGCAGAACAAAATGAGAACCTGCGGAG
CACGTTTTCTGCGCCGACGTCGGCCTTATTTAGCGCTTCGCCTATGGCGCAGCCGAGAACAACCATTTCTGATGCTGAGA
TTTGGGATATGGTTTCCCAAAATATATCGGCGATAGGTGACAGCTACCTGGGCGTTTATGAAAACGTTGTCGCAGTCTAT
ACCGATTTTTATCAGGCCTTCAGTGATATTCTTTCCAAAATGGGAGGCTGGTTATCGCCTGGTAAGGATGGAAATACCAT
TAAGCTAAATGTTGACTCACTTAAAAGTGAAATAAGTAGTTTAATTAATAAATACACTCAAATAAATAAAAATACGATTT
TATTTCCCTCGCAAACTGGCAGCGGAATGACAACAGCAACGAAAGCGGAAGCTGAGCAGTGGATTAAAGAATTGAATTTA
CCGGACAGCTGTCTAAAGGCGTCTGGTTCTGGTTATGTCGTACTGGTGGATACGGGGCCACTGAGCAAAATGGTTAGCGA
TCTTAATGGAATAGGATCGGGTTCAGCCCTTGAACTGGATAACGCCAAATATCAAGCCTGGCAGTCGGGTTTTAAAGCAC
AGGAAGAAAATCTGAAAACCACATTACAGACGCTGACGCAAAAATATAGCAATGCCAATTCATTGTACGACAACCTGGTA
AAAGTGCTGAGCAGTACGATAAGTAGCAGCCTGGAAACCGCCAAAAGCTTCCTGCAAGGATAA

Protein sequence :
MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNL
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLV
KVLSSTISSSLETAKSFLQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipD NP_457277.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 8e-138 100
sipD NP_806486.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 8e-138 100
sipD YP_217802.1 cell invasion protein Virulence SPI-1 Protein 1e-121 88
sipD NP_461804.1 translocation machinery component Virulence SPI-1 Protein 7e-123 88

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sipD NP_457277.1 pathogenicity island 1 effector protein VFG0544 Protein 3e-123 88