Gene Information

Name : sipA
Accession : NP_457276.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein (function unknown)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2876689 - 2878746 bp
Length : 2058 bp
Strand : -
Note : Previously partially sequenced Salmonella typhi SipA TR:P74849 (EMBL:X92546) (450 aa) fasta scores: E(): 0, 100.0% id in 450 aa. Also highly similar to Salmonella typhimurium SipA TR:Q56034 (EMBL:U40013) (684 aa) fasta scores: E(): 0, 95.5% id in 685 aa a

DNA sequence :
ATGGTTACAAGTGTAAGAACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAAAACGCAGGCCACGAATCT
TGCGGCGAATCTTTCCGCGGTCAGAGAAAGTGCCACAGCAACGCTGTCAGGGGAAATTAAAGGCCAGCAACTGGAAGATT
TTCCCGCGCTGATCAAACAGGCGAGTCTGGATGCGTTGTTTAAATGCGGGAAAGACGCCGAGGCGTTAAAAGAAGTTTTT
ACCAATTCAAATAATGTCGCCGGTAAGAAAGCGATAATGGAGTTTGCCGGCCTCTTTCGTTCAGCGCTCAACGCCACCAG
TGATTCTCCTGAGGCGAAGACGCTACTGATGAAGGTGGGGGCAGAGTATACCGCGCAAATCATAAAAGATGGCCTGAAAG
AAAAGTCAGCTTTTGGGCCATGGCTGCCAGAAACAAAGAAAGCGGAAGCGAAGCTGGAAAACCTGGAAAAGCAGCTGTTA
GATATCATCAAAAATAACACTGGCGGTGAATTAAGTAAATTATCGACGAATCTTGTTATGCAGGAGGTGATGCCCTATAT
TGCCAGCTGCATTGAACATAACTTTGGCTGTACGTTAGATCCGTTAACCCGCAGCAGTCTTACGCAGCTTGTTGACAAAG
CGGCGGCGAAGGCGGTTGAGGCGCTTGATATGTGCCACCAAAAATTAACGCAAGAGCAGGGTACCAGCGTAGGACGGGAA
GCCCGGCACCTTGAAATGCAAACGTTGATACCCCTGCTGCTACGTAATGTTTTTGCACAAATTCCTGCAGATAAACTGCC
TGACCCTAAAATTCCGGAACCTGCGGCTGGACCAGTACCTGATGGTGGGAAAAAAGCAGAACCTACGGGTATTAATATCA
ATATTAATATTGATAGCAGTAACCATAGCGTGGATAACAGTAAGCATATTAACAATAGCCGAAGCCATGTCGATAATAGC
CAGCGCCATATCGATAATAGCAACCATGATAATAGCCGGAAGACGATTGATAATAGCCGAACATTTATTGATAACAGCCA
ACGCCATGGCGAGTCACACCATTCGACTAACAGCAGCAACGTAAGTCATAGTCATTCGCGTGTGGATTCGACTACGCATC
AAACGGAGACCGCACACAGCGCCAGCACAGGGACAATTGACCATGGCATCGCGGGTAAAATTGACGTCACGGCTCATGCG
ACGGCAGAGGCTGTGACCAACTCTTCATCCGAAAGTAAAGATGGAAAGGTGGTCACGTCAGAAAAGGGCACTACGGGTGA
AACAACCTCTTTTGATGAAGTCGATGGCGTAACCAGCAAGAGCATTATCGGCAAGCCGTTACAGGCCACGGTGCACGGCG
TTGATGATAATAAACAGCAAAGCCAGACGGCAGAGATTGTGAATGTGAAGCCGCTTGCCAGTCAACTGGCTGGCGTCGAG
AATGTTAAAATCGATACCTTACAATCAGACTCGACGGTAATTACAGGTAATAAAGCCGGTACGACCGATAATGATAATAG
CCAGACAGATAAGACTGGCCCATTTTCTGGTTTGAAGTTTAAGCAAAATAGTTTCCTCTCAACAGTACCGAGCGTTACGA
ATATGCATTCAATACATTTCAACGCCCGTGAGGCGTTTTTGGGTGTGATACGTAAAGCCCTGGAGCCGGATGCCTCTACA
CCGTTTCCTGTACGCAGAGCGTTTGACGGCTTGCGTGGGGAAATATTACCCAATGACACGATAAAGAGTGCAGCGTTGAA
AGCGCAATGTAGCGATATTGACAAGCACCCAGAATTGAAAGCGAAAATGGAGACGCTCAAAGAGGTCATTACTCATCATC
CACAAAAAGAAAAACTGGCTGAGATTGCATTGCAGTTTGCCAGAGAGGCGGGGTTGACCAGGCAAAAAGGGGAAACTGAC
TATGTGTTAAGTAATGTGCTGGACGGCCTTATCGGAGACGGTAGCTGGCGAGCTGGCCCGGCTTACGAGTCATACCTGAA
TAAACCTGGTGTGGATCGGGTTATTACTACCGTTGATGGCTTGCACATGCAGCGTTAA

Protein sequence :
MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATATLSGEIKGQQLEDFPALIKQASLDALFKCGKDAEALKEVF
TNSNNVAGKKAIMEFAGLFRSALNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL
DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSSLTQLVDKAAAKAVEALDMCHQKLTQEQGTSVGRE
ARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAAGPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNS
QRHIDNSNHDNSRKTIDNSRTFIDNSQRHGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGTIDHGIAGKIDVTAHA
TAEAVTNSSSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPLQATVHGVDDNKQQSQTAEIVNVKPLASQLAGVE
NVKIDTLQSDSTVITGNKAGTTDNDNSQTDKTGPFSGLKFKQNSFLSTVPSVTNMHSIHFNAREAFLGVIRKALEPDAST
PFPVRRAFDGLRGEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIALQFAREAGLTRQKGETD
YVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLHMQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipA NP_457276.1 pathogenicity island 1 effector protein (function unknown) Virulence SPI-1 Protein 0.0 100
sipA NP_806485.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 100
sipA NP_461803.1 secreted effector protein Virulence SPI-1 Protein 0.0 98
sipA YP_217801.1 cell invasion protein Virulence SPI-1 Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sipA NP_457276.1 pathogenicity island 1 effector protein (function unknown) VFG0543 Protein 0.0 98