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Name : stpA Accession : NP_457272.1 Strain : Salmonella enterica CT18 Genome accession: NC_003198 Putative virulence/resistance : Virulence Product : tyrosine phosphatase (associated with virulence) Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG2453 EC number : - Position : 2874081 - 2875712 bp Length : 1632 bp Strand : - Note : Previously characterised Salmonella typhi StpA a protein related to both Yersinia YopE cytotoxin and YopH tyrosine phosphatase TR:P74851 (EMBL:X92546) (543 aa) fasta scores: E(): 0, 100.0% id in 543 aa. Also higly similar to Salmonella typhimurium protein DNA sequence : ATGCTAAGGTATGATGAGAGGAAGTTGAATAATTTAACATTGTCTTCATTTTCAAAATCTGGCGTGTCGAGTGATACCCG GCTATATATTGCTAAGGAAAATACTGATAAGGCATATGTTGCGCCTGAAAAATTTTCGTCAAAAGTATTAACCTGGCTTG GAAAAATGCCCTTATTTAAAAACACTGAAGTGGTGCAAAAACACACGGAAAATATCAGAGTACAGAACCAAAAGATTTTA CAGACATTTCTCCAGGCATTAACGGAAAAATATGGGGAAAAAGCGGTCAATAATGCTTTGTACATGTCCAGTATAAATAT GAACAAACCCCTTACCCAACGTTTAGTAGTGCAGATCACGGAGTGTGTAAAAGGTGCTGACGGAGGGTTTATAAATCTTA TTAAGAACAAGGATAATGTTGGTGTCATGAATGCCGCTTTAGTCATAAAAGGCGGCGATACAAAAGTGACAGAACAAAAT AACGATGTTGGTGCAGAAAGTAAGCAACCTTTACTCGATATCGCGCTAAAGGGACTTAAGAGAACAATACCGCAACTGGA ACAAATGGATGGAAATAGCCTGCGAGAAAACTTCCAGGAGATGGCTTCAGGTAACGGCCCGCTGCGTTCATTAATGACGA ATTTACAGAGTTTAAATAAAATTCCAGAGGCTAAACAACTTAATGATTATGTTACAACGTTAAAAAATATTCAGATAGGA GCAGACAGGTTCTCACAATGGGGAACCTGTGGGGGAGAGGTTGAGAGGTGGATTGATAAAGCCTCTACTCATGAATTAAC CCAAGCGGTAAAAAAAATTCACGTTATTGCTAAAGAACTGAAAAACGTTACAGCTGAACTTGAGAAAATAAAAGCCGGTG CGTCAATGCCACAGACGATGAGCGGACCGACACTGGGCCTGGCACGGTTTGCGGTCAGCAGCATTCCCATTAATCAGCAA ACCCAGGTGAAACTGAGCGATGGAATGCCTGTGCCAGTGAATACGTTAACTTTTGACGGTAAGCCTGTGGCATTAGCCGG TTCGTGCCCAAAAAATACGCCGGATGCGCTGGAAGCGCATATGAAAATGCTTCTTGAAAAAGAATGTTCGTGCCTGGTGG TGTTAACGTCGGAAGATCAGATGCAGGCAAAACAATTACCAGCCTATTTCAGAGGGAGCTACACCTTTGGCGAGGTGCAT ACCAACAGCCAAAAAGTGAGCTCAGCCAGTCAGGGAGGAGCGATAGACCAATACAATATGCAACTGTCCTGCGGGGAAAA GCGGTATACAATCCCGGTATTGCATGTGAAAAATTGGCCAGATCACCAGCCGTTACCGTCTACTGATCAGTTAGAATACC TGGCGGATAGGGTGAAAAATAGTAACCAAAATGGCGCGCCGGGGCGTAGTTCATCAGATAAGCATTTACCGATGATTCAT TGTCTGGGCGGAGTGGGAAGAACCGGAACGATGGCGGCGGCTCTTGTACTTAAGGATAATCCTCATAGTAATCTGGAGCA GGTACGTGCAGATTTCCGGAATTCACGGAACAATAGAATGCTGGAAGACGCCTCACAGTTTGTACAACTAAAAGCAATGC AAGCCCAGTTGCTTATGACGACGGCAAGCTGA Protein sequence : MLRYDERKLNNLTLSSFSKSGVSSDTRLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQNQKIL QTFLQALTEKYGEKAVNNALYMSSINMNKPLTQRLVVQITECVKGADGGFINLIKNKDNVGVMNAALVIKGGDTKVTEQN NDVGAESKQPLLDIALKGLKRTIPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQSLNKIPEAKQLNDYVTTLKNIQIG ADRFSQWGTCGGEVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIKAGASMPQTMSGPTLGLARFAVSSIPINQQ TQVKLSDGMPVPVNTLTFDGKPVALAGSCPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPAYFRGSYTFGEVH TNSQKVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIH CLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRNSRNNRMLEDASQFVQLKAMQAQLLMTTAS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| stpA | NP_457272.1 | tyrosine phosphatase (associated with virulence) | Virulence | SPI-1 | Protein | 0.0 | 100 |
| stpA | NP_806481.1 | tyrosine phosphatase | Virulence | SPI-1 | Protein | 0.0 | 100 |
| sptP | NP_461799.1 | protein tyrosine phosphatase/GTPase activating protein | Virulence | SPI-1 | Protein | 0.0 | 95 |
| sptP | YP_217797.1 | protein tyrosine phosphate | Not tested | SPI-1 | Protein | 0.0 | 95 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| stpA | NP_457272.1 | tyrosine phosphatase (associated with virulence) | VFG0540 | Protein | 0.0 | 95 |
