Gene Information

Name : prgH
Accession : NP_457268.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : pathogenicity 1 island effector protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2868356 - 2869534 bp
Length : 1179 bp
Strand : -
Note : Similar to Salmonella typhimurium protein PrgH required for invasion of epithelial cells SW:PRGH_SALTY (P41783) (392 aa) fasta scores: E(): 0, 99.2% id in 392 aa. Contains possible membrane spanning hydrophobic domains.

DNA sequence :
ATGGAAACATCAAAAGAGAAGACGATAACAAGCCCAGGGCCATACATAGTTCGATTACTTAACAGCTCACTGAACGGCTG
TGAGTTTCCATTGCTGACAGGCCGAACACTCTTTGTGGTAGGTCAGAGTGATGCGCTCACTGCTTCAGGCCAACTCCCTG
ATATACCTGCCGATAGCTTTTTTATCCCGCTGGACCATGGCGGAGTAAATTTTGAAATCCAGGTGGATACGGATGCGACC
GAAATTATACTCCATGAGCTGAAAGAAGGAAATCCTGAATCTCGTTCGGTGCAATTAAATACGCCAATACAGGTCGGTGA
ATTGCTTATCCTGATTCGCCCGGAAAGCGAGCCGTGGGTGCCCGAGCAGCCTGAGAAGTTAGAAACGTCTGCAAAAAAGA
ACGAGCCGCGTTTTAAAAACGGAATTGTAGCAGCACTGGCCGGGTTTTTTATATTGGGAATTGGGACGGTGGGGACGTTA
TGGATACTTAACTCGCCGCAGCGGCAGGCCGCAGAGCTCGATTCGTTATTGGGGCAGGAGAAGGAGCGCTTTCAGGTGTT
GCCAGGACGGGACAAAATGCTCTATGTCGCTGCGCAAAATGAAAGAGATACGCTGTGGGCTCGTCAGGTTTTAGCGAGGG
GCGATTATGATAAAAATGCGCGAGTGATTAACGAAAACGAAGAAAATAAGCGTATCTCTACCTGGCTGGATACCTATTAT
CCGCAGCTGGCTTATTATCGGCTTCATTTCGATGAGCCGCGTAAACCCGTTTTCTGGCTAAGCCGCCAGCGAAACACGAT
GAGCAAGAAAGAGCTCGAGGTGTTAAGTCAAAAGCTGAGAGCGCTAATGCCTTACGCGGATTCGGTTAACATCACATTGA
TGGACGATGTTACCGCCGCAGGCCAGGCGGAAGCGGGGCTAAAACAGCAGGCGTTACCTTATTCCCGCAGGAATCATAAG
GGGGGCGTAACGTTTGTTATTCAGGGGGCGCTCGATGATGTAGAAATACTCAGAGCCCGTCAATTTGTCGATAGCTATTA
CCGCACATGGGGAGGACGCTATGTGCAGTTTGCGATCGAATTAAAAGATGACTGGCTCAAGGGGCGCTCATTTCAGTACG
GGGCGGAAGGTTATATCAAAATGAGCCCAGGCCATTGGTATTTCCCAAGCCCACTTTAA

Protein sequence :
METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSDALTASGQLPDIPADSFFIPLDHGGVNFEIQVDTDAT
EIILHELKEGNPESRSVQLNTPIQVGELLILIRPESEPWVPEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTL
WILNSPQRQAAELDSLLGQEKERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDKNARVINENEENKRISTWLDTYY
PQLAYYRLHFDEPRKPVFWLSRQRNTMSKKELEVLSQKLRALMPYADSVNITLMDDVTAAGQAEAGLKQQALPYSRRNHK
GGVTFVIQGALDDVEILRARQFVDSYYRTWGGRYVQFAIELKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prgH NP_457268.1 pathogenicity 1 island effector protein Virulence SPI-1 Protein 0.0 100
prgH NP_806477.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 100
prgH NP_461795.1 needle complex inner membrane protein Virulence SPI-1 Protein 0.0 99
prgH YP_217793.1 cell invasion protein Virulence SPI-1 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
prgH NP_457268.1 pathogenicity 1 island effector protein VFG0536 Protein 0.0 99