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Name : prgK Accession : NP_457265.1 Strain : Salmonella enterica CT18 Genome accession: NC_003198 Putative virulence/resistance : Virulence Product : pathogenicity 1 island effector protein Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG4669 EC number : - Position : 2867010 - 2867768 bp Length : 759 bp Strand : - Note : Similar to several proteins essential for protein secretion by a type III system: Salmonella typhimurium protein precursor PrgK required for invasion of epithelial cells SW:PRGK_SALTY (P41786) (252 aa) fasta scores: E(): 0, 99.6% id in 252 aa and Shigella DNA sequence : ATGATTCGTCGATATCTATATACCTTTCTGCTGGTAATGACCCTTGCCGGCTGTAAGGATAAGGATCTTTTAAAAGGACT GGACCAGGAACAGGCTAATGAGGTCATTGCCGTTCTGCAAATGCACAATATAGAGGCGAATAAAATTGATAGCGGAAAAT TGGGCTATAGCATTACCGTTGCTGAGCCTGATTTTACCGCTGCGGTGTACTGGATTAAAACTTATCAGCTTCCTCCCCGG CCACGGGTGGAAATAGCGCAGATGTTCCCGGCGGATTCGCTGGTATCGTCTCCGCGAGCTGAAAAGGCCAGGTTATATTC GGCTATTGAACAGCGACTGGAACAGTCATTACAGACGATGGAGGGCGTGCTCTCCGCCAGGGTCCATATTAGTTATGATA TTGATGCTGGTGAAAATGGCCGTCCGCCAAAACCTGTTCATCTGTCGGCATTAGCCGTATATGAACGAGGTTCGCCGCTT GCGCATCAGATCAGCGATATCAAGCGTTTCTTAAAGAATAGTTTTGCCGATGTGGATTATGACAACATTTCTGTTGTGTT GTCAGAACGTTCTGATGCCCAATTACAGGCTCCCGGCACACCAGTAAAACGTAATTCTTTTGCAACCAGTTGGATTGTGT TGATTATTTTGTTATCCGTGATGTCAGCAGGCTCTGGCGTCTGGTATTACAAAAACCATTATGCCCGCAATAAGAAAGGC ATAACGGCTGATGATAAGGCGAAATCGTCAAATGAATAG Protein sequence : MIRRYLYTFLLVMTLAGCKDKDLLKGLDQEQANEVIAVLQMHNIEANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPR PRVEIAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALAVYERGSPL AHQISDIKRFLKNSFADVDYDNISVVLSERSDAQLQAPGTPVKRNSFATSWIVLIILLSVMSAGSGVWYYKNHYARNKKG ITADDKAKSSNE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| prgK | NP_457265.1 | pathogenicity 1 island effector protein | Virulence | SPI-1 | Protein | 6e-116 | 100 |
| prgK | NP_806474.1 | pathogenicity island 1 effector protein | Virulence | SPI-1 | Protein | 6e-116 | 100 |
| prgK | YP_217790.1 | cell invasion protein | Virulence | SPI-1 | Protein | 3e-115 | 99 |
| prgK | NP_461792.1 | needle complex inner membrane lipoprotein | Virulence | SPI-1 | Protein | 3e-115 | 99 |
| prgK | AAS66872.1 | PrgK | Virulence | SSR-2 | Protein | 4e-57 | 58 |
| ECs3716 | NP_311743.1 | EprK | Not tested | LIM | Protein | 7e-55 | 56 |
| eprK | AAZ31284.1 | EprK | Virulence | ETT2 | Protein | 8e-54 | 55 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| prgK | NP_457265.1 | pathogenicity 1 island effector protein | VFG0533 | Protein | 1e-115 | 99 |
| prgK | NP_457265.1 | pathogenicity 1 island effector protein | VFG0998 | Protein | 6e-45 | 47 |
| prgK | NP_457265.1 | pathogenicity 1 island effector protein | VFG1787 | Protein | 2e-37 | 46 |
