Gene Information

Name : sprA
Accession : NP_457261.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : possible AraC-family transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG2207
EC number : -
Position : 2864110 - 2864997 bp
Length : 888 bp
Strand : -
Note : Similar to Salmonella typhimurium transcriptional regulator SprA or HilC found on pathogenicity island 1 TR:Q9R3W3 (EMBL:AF148689) (295 aa) fasta scores: E(): 0, 99.3% id in 295 aa

DNA sequence :
ATGGTATTGCCTTCAATGAATAAATCAGTTGAGGCCATTAGCAATAATCACCTTCAACAACCGAACAAATTTCCATTAAT
AAATGGATTAGCTGACGTAAGAGACTATTATGTCGCAAACTGCTTATTGTTTAAACTTAATAAAGGCAGTTTGCGAATTG
AAAACGAATTTGGGGAGTTCATCGAACAATCTGCGCTGTGTTTATTTTTATTGGAAAAAGATCAAACAATCACGCTTAGT
ATGAGCGAAATAGAAGGACATATTGATTTTTCTTCACTGGAAGTTTCCTATGACTTAATGCAAAAATTCTACAAAGTTTT
TTACAGTACAAGAAACTATAATGATCGAGAGCTATCATTAAAAACGAAACCAAAGTATTTTTTTCATGCGGACTTGTTGC
CAGGGATGAGTGATACTTTTGACTCTATTTTGCATGGTGTCGCATGTCCACGGGTTTGTAGTAATGTGAGTATTGATGAT
CATGATTATTCATATTTCTCATTGATGTATCTTATATCGGCATTTGTACGTAAGCCCGGTGGGTTTGATTTCCTTGAGCG
AGCAATAAAAATTACAACAAAAGAGAAAGTTTATAACATTATTATCAGCGATCTCACCCGCAAATGGTCACAGGCTGAGG
TGGCAGGAAAGCTGTTTATGAGCGTATCAAGTCTGAAGCGAAAACTGGCCGCTGAAGAGGTGAGTTTTAGCAAAATATAC
TTGGATGCTCGTATGAATCAGGCTATAAAATTATTACGTATGGGTGCTGGAAATATTTCACAAGTCGCGACGATGTGTGG
CTATGATACGCCTTCTTATTTTATCGCTATTTTTAAACGGCATTTTAAGATTACACCGCTTAGCTTTATGCGTACAATGA
ACCATTGA

Protein sequence :
MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEFIEQSALCLFLLEKDQTITLS
MSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSLKTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDD
HDYSYFSLMYLISAFVRKPGGFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIY
LDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sprA NP_457261.1 possible AraC-family transcriptional regulator Virulence SPI-1 Protein 1e-137 100
sprA NP_806470.1 AraC family transcriptional regulator Virulence SPI-1 Protein 1e-137 100
sprA AAD37784.1 transcriptional regulator SprA Virulence SPI-1 Protein 1e-136 99
hilC NP_461788.1 invasion regulatory protein Virulence SPI-1 Protein 2e-136 99
hilC YP_217786.1 AraC family transcriptional regulator Not tested SPI-1 Protein 7e-137 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sprA NP_457261.1 possible AraC-family transcriptional regulator VFG0531 Protein 7e-137 99