Gene Information

Name : sitC
Accession : NP_457257.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : Iron transport protein, inner membrane component
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 2860994 - 2861854 bp
Length : 861 bp
Strand : +
Note : Similar to Salmonella typhimurium SitC an iron transport protein located on centisome 63 pathogenicity island TR:Q9XCS0 (EMBL:AF128999) (286 aa) fasta scores: E(): 0, 99.7% id in 286 aa and to Yersinia pestis chelated iron transport system membrane protei

DNA sequence : 
ATGAACTGGCTTGTTGAGCCGTTTGGCTACCAGTATATGCTCAACGCGATGTGGGTCTCCGCGATGGTGGGCGGTCTTTG
CGCGTTTCTCTCCTGCTATTTGATGCTCAAAGGCTGGTCGCTCATTGGCGATGCGCTATCTCACTCTATTGTGCCTGGCG
TCGCTGGCGCCTGGATGTTAGGGCTGCCCTTCTCGCTCGGCGCGTTTCTTTCCGGCGGACTGGCGGCAGGCAGTATGCTC
TTTCTTAACCAACGCTCACGCCTGAAAGAAGACGCGATTATCGGGCTTATCTTCTCCTCTTTTTTTGGCGTCGGCCTTTT
TATGGTGTCGCTCAATCCGATGTCGGTGAATATCCAGACGATTATTCTCGGCAACGTGCTGGCGATCGCGCCAGCGGATA
TTACGCAACTGGCGATTATCGGCGCAGTCTCGCTGACGATTCTGCTGTTAAAGTGGAAAGATCTGATGGTCGTCTTTTTC
GATGAGACCCATGCGCGTTCTATCGGGCTTAATCCGGGTCGACTAAAATTGTTGTTTTTCACTCTATTGTCCGTCTCTAC
CGTGGCGGCCCTGCAAACCGTTGGGGCGTTCCTGGTGATCTGTCTCGTCGTCACGCCGGGCGCGACGGCCTGGTTACTCA
CCGACCGTTTTCCACGTCTGCTCATGATTGCCGTCGTGATTGGCAGCCTGACCAGTTTTCTGGGCGCATGGCTTAGCTAC
TGGCTGGATGGCGCCACTGGCGGAATTATTGTCGTCATGCAAACCTTACTGTTCATCACGGCCTTTATTTTCGCCCCGAA
ACACGGTCTGTTAGCCAACCGTCGACGCGCCCGCCTGCAGAAGGAGCCGACATGTTCTTAG

Protein sequence : 
MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAWMLGLPFSLGAFLSGGLAAGSML
FLNQRSRLKEDAIIGLIFSSFFGVGLFMVSLNPMSVNIQTIILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFF
DETHARSIGLNPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLMIAVVIGSLTSFLGAWLSY
WLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRRARLQKEPTCS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 5e-115 100
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 5e-115 100
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 5e-115 99
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 7e-115 99
sitC NP_461784.1 permease Virulence SPI-1 Protein 7e-115 99
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 4e-39 42
sitD NP_461785.1 permease Virulence SPI-1 Protein 5e-39 42
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 9e-39 41
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 9e-39 41
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 9e-39 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC NP_457257.1 Iron transport protein, inner membrane component BAC0351 Protein 3e-115 99
sitC NP_457257.1 Iron transport protein, inner membrane component BAC0441 Protein 6e-75 66
sitC NP_457257.1 Iron transport protein, inner membrane component BAC0352 Protein 2e-39 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC NP_457257.1 Iron transport protein, inner membrane component VFG0527 Protein 3e-115 99
sitC NP_457257.1 Iron transport protein, inner membrane component VFG0528 Protein 2e-39 42