Gene Information

Name : sitA
Accession : NP_457255.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : Iron transport protein, periplasmic-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 2859262 - 2860179 bp
Length : 918 bp
Strand : +
Note : Similar to Salmonella typhimurium SitA, an iron transport protein located on centisome 63 pathogenicity island TR:Q9XCS2 (EMBL:AF128999) (305 aa) fasta scores: E(): 0, 100.0% id in 305 aa and to Yersinia pestis YfeA TR:Q56952 (EMBL:U50597) (322 aa) fasta

DNA sequence : 
ATGACGAATCTACATCGTCTAAAAACACTCCTGATTGCCGGTATTGTCGCGATACTCGCGCTATCGCCAGCCTATGCAAA
AGAGAAATTTAAAGTCATCACCACGTTTACCGTTATTGCCGACATGGCGAAAAACGTGGCGGGCGACGCAGCGGAAGTCA
GCTCGATTACCAAGCCCGGCGCTGAAATCCATGAGTATCAGCCAACGCCCGGCGATATTAAACGAGCGCAGGGGGCACAG
CTTATCCTCGCGAATGGTCTGAACCTGGAGCGATGGTTCGCCCGCTTTTATCAGCACCTTTCCGGTGTACCGGAAGTCGT
CGTCTCCACCGGCGTCAAACCGATGGGCATTACCGAAGGCCCGTATAACGGTAAACCGAACCCGCACGCCTGGATGTCGG
CAGAAAACGCGCTGATTTATGTCGATAACATTCGCGACGCCCTGGTGAAGTACGATCCGGATAATGCGCAGATCTATAAG
CAAAATGCCGAACGCTATAAAGCGAAAATTCGCCAGATGGCCGATCCGTTGCGTGCCGAGCTGGAAAAAATTCCCGCCGA
TCAGCGCTGGCTGGTCACCAGTGAAGGCGCGTTCTCTTACCTGGCGCGCGATAACGACATGAAAGAGCTTTATCTCTGGC
CAATTAACGCCGATCAACAGGGGACGCCAAAACAGGTGCGTAAAGTGATTGATACCATTAAAAAGCACCATATTCCCGCC
ATCTTTAGCGAGAGTACGGTTTCCGATAAACCCGCCCGCCAGGTCGCGCGTGAATCCGGCGCGCATTATGGCGGCGTACT
GTATGTCGATTCTCTGAGCGCCGCTGACGGCCCTGTGCCAACCTATCTGGATCTGCTGCGCGTCACGACCGAAACCATCG
TCAACGGCATTAACGACGGACTGAGGAGTCAACAATGA

Protein sequence : 
MTNLHRLKTLLIAGIVAILALSPAYAKEKFKVITTFTVIADMAKNVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQ
LILANGLNLERWFARFYQHLSGVPEVVVSTGVKPMGITEGPYNGKPNPHAWMSAENALIYVDNIRDALVKYDPDNAQIYK
QNAERYKAKIRQMADPLRAELEKIPADQRWLVTSEGAFSYLARDNDMKELYLWPINADQQGTPKQVRKVIDTIKKHHIPA
IFSESTVSDKPARQVARESGAHYGGVLYVDSLSAADGPVPTYLDLLRVTTETIVNGINDGLRSQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 3e-135 100
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 3e-135 100
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 2e-135 100
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 3e-135 100
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-135 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein BAC0349 Protein 1e-135 100
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein BAC0439 Protein 8e-90 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein VFG0525 Protein 1e-135 100