Gene Information

Name : STY2180
Accession : NP_456533.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 2023515 - 2024885 bp
Length : 1371 bp
Strand : +
Note : Similar to Salmonella typhimurium flagellum-specific ATP synthase fliI or flaC SW:FLII_SALTY (P26465) (456 aa) fasta scores: E(): 0, 99.6% id in 456 aa; Fasta hit to ATPB_ECOLI (459 aa), 30% identity in 416 aa overlap; Orthologue of E. coli fliI (FLII_ECO

DNA sequence :
ATGACCACGCGCCTGACCCGCTGGCTTACCGCGCTCGACAACTTTGAAGCAAAAATGGCGTTATTGCCGGCGGTGCGCCG
TTATGGACGTTTAACCCGCGCCACTGGCCTGGTACTGGAGGCCACCGGTCTCCAGCTTCCGCTGGGCGCCACCTGCATTA
TTGAGCGCCAGGACGGCCCTGAAACCAAAGAGGTGGAATCGGAAGTCGTCGGTTTTAACGGCCAGCGTCTGTTTTTAATG
CCGCTGGAAGAGGTCGAAGGCATTCTGCCCGGTGCCCGCGTTTACGCCCGTAACGGGCATGGCGACGGTCTGCAAAGCGG
CAAACAGTTACCGCTCGGCCCGGCCCTGCTTGGTCGGGTGCTGGATGGCGGCGGTAAACCGCTCGACGGACTGCCTGCGC
CGGATACGCTGGAAACCGGCGCGTTAATCACGCCGCCGTTTAACCCGCTACAGCGAACGCCAATCGAACATGTGCTGGAA
ACCGGCGTACGCGCCATCAACGCGTTGTTAACCGTAGGGCGCGGTCAGCGTATGGGACTCTTTGCCGGTTCCGGCGTCGG
TAAATCGGTTCTGCTTGGCATGATGGCGCGCTACACACGGGCGGACGTGATTGTCGTGGGTCTTATCGGCGAACGTGGCC
GCGAAGTTAAAGATTTTATCGAAAATATTCTCGGCCCCGACGGTCGCGCGCGTTCGGTGGTGATCGCCGCCCCGGCGGAT
GTTTCGCCGCTGCTGCGAATGCAGGGCGCCGCCTATGCCACCCGCATCGCCGAAGACTTTCGCGATCGCGGACAGCATGT
GTTGCTGATTATGGATTCGCTGACGCGCTATGCGATGGCGCAGCGTGAAATTGCCCTGGCAATCGGCGAACCGCCAGCCA
CCAAAGGTTATCCGCCCTCGGTGTTCGCAAAGCTGCCAGCGCTGGTCGAGCGTGCCGGTAATGGCATCCACGGCGGCGGC
TCTATCACCGCGTTTTATACCGTATTGACCGAGGGGGACGACCAACAAGATCCCATTGCCGACTCGGCACGCGCAATCCT
CGACGGGCACATTGTCTTGTCCCGCCGCCTGGCGGAAGCCGGGCACTACCCGGCCATTGATATCGAGGCGTCAATCAGCC
GGGCGATGACCGCGCTCATTACCGAGCAGCACTATGCGCGGGTACGGCTATTTAAACAATTGCTTTCCAGTTTCCAGCGT
AACCGCGATCTGATCAGCGTCGGCGCCTATGCCAAAGGCAGCGATCCGATGCTCGATAAAGCCATTACCTTATGGCCGCA
ATTAGAAGCGTTTTTACAGCAAGGCATTTTTGAACGGGCCGACTGGGAGGACTCTCTTCAGGCGCTCGATTTAATTTTCC
CGACGGTGTGA

Protein sequence :
MTTRLTRWLTALDNFEAKMALLPAVRRYGRLTRATGLVLEATGLQLPLGATCIIERQDGPETKEVESEVVGFNGQRLFLM
PLEEVEGILPGARVYARNGHGDGLQSGKQLPLGPALLGRVLDGGGKPLDGLPAPDTLETGALITPPFNPLQRTPIEHVLE
TGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGPDGRARSVVIAAPAD
VSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGIHGGG
SITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALITEQHYARVRLFKQLLSSFQR
NRDLISVGAYAKGSDPMLDKAITLWPQLEAFLQQGIFERADWEDSLQALDLIFPTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-78 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-78 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-78 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-77 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-77 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-75 47
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-77 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-76 47
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-75 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-69 46
escN AAC31513.1 L0034 Virulence LEE Protein 1e-67 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-67 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-67 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-67 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-67 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-63 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-63 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-63 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-63 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-63 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-68 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-68 45
escN AAC38383.1 EscN Virulence LEE Protein 1e-67 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-67 45
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-68 45
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-66 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-67 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-63 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-62 44
escN AAK26715.1 EscN Virulence LEE Protein 2e-67 44
escN AAL57542.1 EscN Virulence LEE Protein 2e-67 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-67 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-66 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-66 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-66 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-71 43
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-68 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 9e-61 41
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 9e-61 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG2331 Protein 2e-167 84
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG2499 Protein 6e-140 70
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG1254 Protein 1e-114 61
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG2144 Protein 1e-78 46
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG0048 Protein 1e-76 46
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG0192 Protein 8e-68 46
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG0812 Protein 6e-68 46
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG0515 Protein 1e-63 46
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG0730 Protein 6e-68 45
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG0390 Protein 5e-68 43
STY2180 NP_456533.1 flagellum-specific ATP synthase VFG2459 Protein 6e-63 42