Gene Information

Name : pagC
Accession : NP_456268.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : outer membrane invasion protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3637
EC number : -
Position : 1781177 - 1781734 bp
Length : 558 bp
Strand : -
Note : Similar to Salmonella typhimurium virulence membrane protein pagc precursor. virulence membrane protein pagc precursor SW:PAGC_SALTY (P23988) (188 aa) fasta scores: E(): 0, 95.2% id in 188 aa, and to Salmonella typhimurium RcK protein precursor rcK TR:Q04

DNA sequence : 
ATGAAAAATATTATTTTATCCACTTTAGTTATTACTACAAGCGTTTTGGTTGTAAATGTTGCACAGGCCGATACTAACGC
CTTTTCCGTGGGGTATGCACAAAGTAAAGTTCAGGATTTCAAAAATATCCGAGGGGTAAATGTGAAATACCGTTATGAGG
ATGACTCTCCGGTAAGTTTTATTTCCTCGCTAAGTTACTTATATGGAGACAGCCAGGATTCCGGGTCTATTGAGTCTGAA
GGTATCCATTACCATGACAAGTTTGAGGTGAAATATGGTTCTTTAATGGTTGGGCCAGCCTATCGATTGTCTGACAATTT
TTCGTTATACGCGCTGGCAGGTGTCGGCACGGTAAAGGCGACATTTAAAGAACATGCCACTCAGGATGGCGATTCTTTTT
CTAACAAAATTTCCTCAAGGAAAACGGGATTTGCCTGGGGCGCGGGTGTACAGATGAATCCGCTGGAGAATATCGTCGTC
GATGTTGGGTATGAAGGAAGCAACATCTCCTCTACAAAAATAAACGGCTTCAACGTCGGAATTGGATACCGTTTCTGA

Protein sequence : 
MKNIILSTLVITTSVLVVNVAQADTNAFSVGYAQSKVQDFKNIRGVNVKYRYEDDSPVSFISSLSYLYGDSQDSGSIESE
GIHYHDKFEVKYGSLMVGPAYRLSDNFSLYALAGVGTVKATFKEHATQDGDSFSNKISSRKTGFAWGAGVQMNPLENIVV
DVGYEGSNISSTKINGFNVGIGYRF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pagC YP_216243.1 PhoP regulated protein: reduced macrophage survival Not tested SPI-11 Protein 2e-70 97
Z4321 NP_289546.1 PagC-like membrane protein Not tested OI-122 Protein 2e-27 47
unnamed ADD91732.1 putative PagC-like membrane protein Not tested PAI-I AL862 Protein 1e-27 47
Z4321 AAQ19134.1 putative PagC-like membrane protein Not tested PAI I CL3 Protein 5e-27 46
pagC AGI37348.1 PagC Virulence OI-122 Protein 7e-20 44
pagC AGI37351.1 PagC Virulence OI-122 Protein 6e-20 44
pagC AGI37352.1 PagC Virulence OI-122 Protein 8e-19 43
pagC AGI37337.1 PagC Virulence OI-122 Protein 3e-19 43
pagC AGI37342.1 PagC Virulence OI-122 Protein 3e-19 43
pagC AGI37344.1 PagC Virulence OI-122 Protein 3e-19 43
pagC AGI37346.1 PagC Virulence OI-122 Protein 3e-19 43
pagC AGI37350.1 PagC Virulence OI-122 Protein 3e-19 43
pagC AGI37340.1 PagC Virulence OI-122 Protein 2e-19 43
pagC AGI37341.1 PagC Virulence OI-122 Protein 8e-19 43
pagC AGI37347.1 PagC Virulence OI-122 Protein 2e-19 43
pagC AGI37349.1 PagC Virulence OI-122 Protein 8e-19 43
pagC AGI37343.1 PagC Virulence OI-122 Protein 1e-18 42
pagC AGI37353.1 PagC Virulence OI-122 Protein 1e-18 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pagC NP_456268.1 outer membrane invasion protein VFG0442 Protein 3e-37 53