Gene Information

Name : STY1816
Accession : NP_456214.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1734647 - 1736596 bp
Length : 1950 bp
Strand : -
Note : Orthologue of E. coli topB (TOP3_ECOLI); Fasta hit to TOP3_ECOLI (653 aa), 94% identity in 648 aa overlap

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGGGCGCGCCATTGCGGATGTGCTGCCAAAACCGCACCGTAAAGGCGA
TGGTTTTATTGAGTGCGGAAACGGGCAGGTCGTCACCTGGTGTATTGGTCATTTGCTGGAACAGGCGCAGCCGGATGCGT
ATGACAGCCGTTATGCGCGCTGGAATCTGGCTGACCTGCCTATCGTGCCGGAAAAATGGCAGCTTCAGCCTCGTCCTTCC
GTCACCAAACAGCTCAATGTGATTAAGCGCTTTTTGCATCAAGCCGGTGAAATTATTCACGCCGGCGACCCGGATCGCGA
AGGGCAGCTTCTGGTTGATGAAGTGCTGGATTATCTCCAGCTTCCTGCCGAAAAGCGCCAGCAGGTACGGCGTTGTCTGA
TAAACGACCTTAACCCGCAGGCGGTCGAGCGTGCTATCGACAGGCTGCGGGCGAACAGCGACTTCGTGCCGCTGTGCGTC
TCCGCGCTGGCGCGAGCGCGAGCGGACTGGCTGTATGGCATTAATATGACCCGTGCTTACACGATCCTGGGCCGTAATGC
CGGCTATCAGGGCGTGTTATCCGTGGGACGCGTGCAGACGCCGGTACTGGGGCTGGTGGTGCGGCGAGACGAAGAGATTG
AGAACTTCGTCGCCAAAGACTTCTTTGAAGTGAAGGCGCACATCGTTACGCCTGCCGACGAGCGTTTTACCGCTATCTGG
CAGCCGAGCGAGGCGTGCGAACCTTATCAGGATGAAGAGGGGCGTTTGCTTCATCGTCCGCTGGCGGAGCATGTGGTGAA
CCGAATCAACGGTCAGCCTGCGCTGGTAACCAGTTATAATGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGC
TCTCGACGCTACAGATTGAAGCCGCTAAACGTTTTGGCCTGAGCGCGCAAAACGTGCTTGATATTTGTCAGAAGCTATAT
GAAACCCACAAACTGATTACCTATCCGCGTTCCGACTGCCGTTATCTGCCGGAAGAACACTTTGCCGGACGGCAGGCGGT
CATGAACGCGATTAGCGTCCACGCCCCGGATTTACTGCCGCAGCCTGTGGTTAATCCTGATACGCGCAATCGCTGCTGGG
ATGACAAAAAAGTGGATGCGCACCACGCGATTATCCCGACGGCGCGCAGTTCTTCTGTCCATCTGACGGAAAACGAAGCG
AAAGTGTACACCCTGATTGCGCGTCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTTCGTAAATGCGTTATTGAACT
GGAAATCGCCAAAGGGAAATTTGTCGCCAAAGCGCGTTTTCTGGCGGAGGCCGGTTGGCGGACGTTACTGGGCAGTAAAG
AGCGCGACGAGGAAAACGACGGTACGCCGCTGTCGGTTGTCGCCAAAGGTGATGAGTTGCTGTGTGAAAAGGGGGAAGTG
GTCGAACGCCAAACCCAGCCGCCGCGTCATTTCACTGATGCGACATTGCTTTCCGCGATGACCGGAATTGCCCGCTTCGT
GCAGGATAAAGATCTGAAAAAGATCCTGCGCGCGACCGATGGGCTGGGGACGGAAGCCACGCGCGCCGGGATTATCGAAC
TGCTGTTCAAACGTAGCTTTCTGACCAAAAAAGGGCGCTACATTCATTCTACCGATGCTGGCAAAGCGTTAATACATTCG
CTGCCGGAGATGGCGGCCCGTCCAGATATGACCGCGCACTGGGAATCTGTTTTGACGCAAATCAGCGAAAAGCAGTGCCG
TTACCAGGATTTTATGCAACCGCTGGTCGGCACGTTATATCAGCTGATCGATCAGGCTAAGCGCACGCCGGTGAAGCGTT
TCAGAGGGATAGTCGCGCCAGGCGGCGGAGAAAAGAAAAAGAGCGCGCCGCGTAAGCGAGCGGGCAAAAAAAGCCCGCCT
GCTGAGGAGACAGGCCGTCAGACCGAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEA
KVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLSVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHS
LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPP
AEETGRQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 5e-110 41