Gene Information

Name : ssrB
Accession : NP_456137.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : putative two-component response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 1649864 - 1650502 bp
Length : 639 bp
Strand : +
Note : Similar to Salmonella typhimurium SsrB TR:O54305 (EMBL:Z95891) (193 aa) fasta scores: E(): 0, 100.0% id in 193 aa, and to Streptococcus pneumoniae response regulator rr03 TR:Q9S1J7 (EMBL:AJ006393) (210 aa) fasta scores: E(): 1.4e-19, 34.5% id in 206 aa.;

DNA sequence : 
ATGAAAGAATATAAGATCTTATTAGTAGACGATCATGAAATCATCATTAACGGCATTATGAATGCCTTATTACCCTGGCC
TCATTTTAAAATTGTAGAGCATGTTAAAAATGGTCTTGAGGTTTATAATGCCTGTTGCGCATACGAGCCTGACATACTTA
TCCTTGATCTTAGCTTACCTGGCATCAATGGCCTGGATATCATTCCTCAATTACATCAGCGTTGGCCAGCAATGAATATT
CTGGTTTACACAGCATACCAACAAGAGTATATGACCATTAAAACTTTAGCCGCAGGTGCTAATGGCTATGTTTTAAAAAG
CAGTAGTCAGCAAGTCCTGTTAGCGGCATTGCAAACAGTCGCAGTAAACAAGCGTTACATTGACCCGACGTTGAATCGGG
AAGCTATCCTGGCTGAATTAAACGCTGACACGACCAATCATCAACTGCTTACTTTGCGCGAGCGTCAGGTTCTTAAACTT
ATTGACGAGGGGTATACCAATCATGGGATCAGCGAAAAGCTACATATCAGTATAAAAACCGTCGAAACACATCGGATGAA
TATGATGAGAAAGCTACAGGTTCATAAAGTGACAGAGTTACTTAACTGCGCCCGAAGAATGAGGTTAATAGAGTATTAA

Protein sequence : 
MKEYKILLVDDHEIIINGIMNALLPWPHFKIVEHVKNGLEVYNACCAYEPDILILDLSLPGINGLDIIPQLHQRWPAMNI
LVYTAYQQEYMTIKTLAAGANGYVLKSSSQQVLLAALQTVAVNKRYIDPTLNREAILAELNADTTNHQLLTLRERQVLKL
IDEGYTNHGISEKLHISIKTVETHRMNMMRKLQVHKVTELLNCARRMRLIEY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssrB NP_456137.1 putative two-component response regulator Virulence SPI-2 Protein 3e-97 100
ssrB NP_805062.1 two-component response regulator Virulence SPI-2 Protein 3e-97 100
ssrB NP_460356.1 transcriptional activator Virulence SPI-2 Protein 3e-97 100
ssrB CAB09344.1 SsrB Virulence SPI-2 Protein 3e-88 100
ssrB YP_216399.1 secretion system transcriptonal activator Virulence SPI-2 Protein 5e-97 99
YPO0255 YP_002345335.1 two-component response regulator Not tested Not named Protein 7e-48 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ssrB NP_456137.1 putative two-component response regulator VFG0492 Protein 1e-97 100