Gene Information

Name : ssrA
Accession : NP_456136.1
Strain : Salmonella enterica CT18
Genome accession: NC_003198
Putative virulence/resistance : Virulence
Product : putative two-component sensor kinase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0642
EC number : -
Position : 1647071 - 1649833 bp
Length : 2763 bp
Strand : +
Note : Similar to Salmonella typhimurium SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 98.1% id in 823 aa, and to Escherichia coli sensor protein TorS SW:TORS_ECOLI (P39453; P75887) (904 aa) fasta scores: E(): 1.3e-26, 27.8% id in 598 aa

DNA sequence :
ATGAATTTGCTCAATCTCAAGAATACGCTGCAAACATCTTTAGTAATCAGGCTAACTTTTTTATTTTTATTAACAACCAT
AATTATTTGGCTGCTATCTGTGATTACTGCAGCTTATATATCAATGGTTCAGAAACGGCAGCATATAATAGAGGATTTAT
CCGCTCTATCCGAGATGAATATTGTACTAAGCAATCAACGATTTGAAGAGGCTGAACGTGACGCTAAAAATTTAATGTAT
CAATGCTCATTAGCGACTGAGATTCATCATAATGATATTTTCCCTGAGGTGAGCCGGCATCTTTCTGTCGGTCCTTCAAA
TTGCACGCCGACGCTAAACGGAGAGAAGCATCGTCTCTTTCTGCAGTCCTCTGATATCGATGAAAAAAGCTTTCGTCGCG
ATAGTTTTATTCTTAACCATAAAAATGAGATTTCGTTATTATCTACTGATAACCCTTCAGATTATTCAACTCTACAGCTT
TTAACGCGAAAAAGCTTTCCTTTATACCCAACCCATGCCGGGTTTTACTGGAGTGAACCAGAATACATAAACGGCAAAGG
ATGGCACGCTTCCGTTGCGGTTGCCGATCAGCAAGGCGTATTTTTTGGGGTGATGGTTAAACTTCCTGATCTCATTTCTA
AGAGCCACCTACCATTAGATGATAGTATTCGAGTATGGCTGGATCAAAACAACCACTTATTGCCGTTTTCATACATCCCG
CAAAAAATACGTACACAGTTAGAAAATGTAACGCTGCATGATGGATGGCAACAAATTCCCGGATTTCTGATATTACGCAC
AACTTTGCATGGCCCCGGATGGAGTCTGGTTACGCTGTACCCATACGGTAATCTACATAATCGCATCTTAAAAACTATCC
TCCAACAAATCCCCTTTACATTAACAGCATTGGTGTTGATGACGTCGGCTTTTTGCTGGTTACTACATCGCTCACTGGCC
AAACCGTTATGGCGTTTTGTCGATATCATTAATAAAACCGCAACTGCACCGCTGAGCACACGTTTACCAGCACAACGACT
GGATGAATTAGATAGTATTGCCGGTGCTTTTAACCAACTACTTGATACCCTACAAGTCCAATACGACAATCTGGAAAACA
AAGTCGCAGAGCGCACCCAGGCGCTAAATGAAGCAAAAAAACGCGCTGAGCAAGCTAACAAACGTAAAAGCATTCATCTT
ACGGTAATAAGTCATGAGTTACGTACTCCGATGAATGGCGTACTCGGTGCAATTGAATTATTACAAACCACCCCTTTAAA
CATAGAGCAGCAAGGATTAGCTGATACCGCCAGAAATTGCACACTGTCTTTGTTAGCTATTATTAATAATCTGCTGGATT
TTTCACGCATCGAGTCTGGTCATTTCACATTACATATGGAAGAAACAGCGTTACTGCCGTTACTGGACCAGGCAATGCAA
ACCATCCAGGGGCCAGCACAAAGCAAAAAACTGTCATTACGTACTTTTGTTGGTCAACATGTCCCCCTCTATTTTCATAC
CGACAGTATCCGTTTACGGCAAATTTTGGTTAATTTACTCGGGAACGCGGTAAAATTTACCGAAACCGGAGGGATACGTC
TGACGGTCAAGCGTCATGAGGAACAATTAATATTTCTGGTTAGCGATAGCGGTAAAGGGATTGAAATACAGCAGCAGTCT
CAAATCTTTACTGCTTTTTATCAAGCAGACACAAATTCGCAAGGTACAGGAATTGGACTGACTATTGCGTCAAGCCTGGC
TAAAATGATGGGCGGTAATCTGACACTAAAAAGTGTCCCCGGGGTTGGAACCTGTGTCTCGCTAGTATTACCCTTACAAG
AATACCAACCGCCTCAACAAATTAAAGGGACACTGTCAGCGCCGTTCTGCCTGCATCGCCAACTGGCTTGCTGGGGAATA
CGCGGCGAACCACCCCACCAGCAAAATGCGCTTCTCAACGCTGAGTTTTTGTATTTCCCCGGAAAACTCTACGACCTGGC
GCAACAGTTAATATTGTGTACACCAAATATACCAATAATAAATAATTTGTTACCACCCTGGCAGTTACAGATTCTTTTGG
TTGATGATGCCGATATTAATCGGGATATCATCGGCAAAATGCTTGTCAGCCTGGGCCAACACGTCACTATTGCCGCCAGT
AGTAACGAGGCTCTGACTTTATCACAACAGCAACGATTCGATTTAGTACTGATTGACATTAGAATGCCAGAAATAGATGG
TATTGAATGTGTACAATTATGGCACGATGAGCCGAATAATTTAGATCCTGACTGCATGTTTGTGGCGCTATCCGCTAGCG
TAGCGACAGAAGATATTCATCGTTGTAAAAAAAATGGGATTCATCATTACATTACCAAACCAGTGACGTTGGCTACCTTA
GCTCGCTATATCAGTATTGCCGCAGAATACCAACTTTTACGAAATATAGAGCTACAGGAGCAGGATCCAAGTCGCTGCTC
AGCGCTACTGGCGACAGATGATATGGTCATTAATAGCAAGATTTTCCAATCACTGGACCTCTTGCTGGCTGATATTGAAA
ATGCCGTATCGGCTGGAAAAAAAATCGATCAGTTAATTCACACATTAAAAGGCTGTTTAGGTCAAATAGGGCAGACTGAA
TTGGTATGCTATGTCATAGACATTGAGAATCGCGTAAAAATGGGGAAAATCATCGCGCTGGAAGAACTAACCGACTTACG
CCAGAAAATACGTATGATCTTCAAAAACTACACCATTACTTAA

Protein sequence :
MNLLNLKNTLQTSLVIRLTFLFLLTTIIIWLLSVITAAYISMVQKRQHIIEDLSALSEMNIVLSNQRFEEAERDAKNLMY
QCSLATEIHHNDIFPEVSRHLSVGPSNCTPTLNGEKHRLFLQSSDIDEKSFRRDSFILNHKNEISLLSTDNPSDYSTLQL
LTRKSFPLYPTHAGFYWSEPEYINGKGWHASVAVADQQGVFFGVMVKLPDLISKSHLPLDDSIRVWLDQNNHLLPFSYIP
QKIRTQLENVTLHDGWQQIPGFLILRTTLHGPGWSLVTLYPYGNLHNRILKTILQQIPFTLTALVLMTSAFCWLLHRSLA
KPLWRFVDIINKTATAPLSTRLPAQRLDELDSIAGAFNQLLDTLQVQYDNLENKVAERTQALNEAKKRAEQANKRKSIHL
TVISHELRTPMNGVLGAIELLQTTPLNIEQQGLADTARNCTLSLLAIINNLLDFSRIESGHFTLHMEETALLPLLDQAMQ
TIQGPAQSKKLSLRTFVGQHVPLYFHTDSIRLRQILVNLLGNAVKFTETGGIRLTVKRHEEQLIFLVSDSGKGIEIQQQS
QIFTAFYQADTNSQGTGIGLTIASSLAKMMGGNLTLKSVPGVGTCVSLVLPLQEYQPPQQIKGTLSAPFCLHRQLACWGI
RGEPPHQQNALLNAEFLYFPGKLYDLAQQLILCTPNIPIINNLLPPWQLQILLVDDADINRDIIGKMLVSLGQHVTIAAS
SNEALTLSQQQRFDLVLIDIRMPEIDGIECVQLWHDEPNNLDPDCMFVALSASVATEDIHRCKKNGIHHYITKPVTLATL
ARYISIAAEYQLLRNIELQEQDPSRCSALLATDDMVINSKIFQSLDLLLADIENAVSAGKKIDQLIHTLKGCLGQIGQTE
LVCYVIDIENRVKMGKIIALEELTDLRQKIRMIFKNYTIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssrA NP_456136.1 putative two-component sensor kinase Virulence SPI-2 Protein 0.0 100
spiR AAC44299.1 SpiR Virulence SPI-2 Protein 0.0 99
ssrA NP_460357.1 sensor kinase Virulence SPI-2 Protein 0.0 99
ssrA YP_216400.1 secretion system regulator:sensor component Virulence SPI-2 Protein 0.0 99
ssrA NP_805063.1 two-component sensor kinase Virulence SPI-2 Protein 0.0 99
YPO0256 YP_002345336.1 two-component sensor/regulator Not tested Not named Protein 3e-168 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ssrA NP_456136.1 putative two-component sensor kinase VFG0493 Protein 0.0 99