Gene Information

Name : kdsB (STM0988)
Accession : NP_459963.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1074664 - 1075410 bp
Length : 747 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTCGTCGTCATCATTCCGGCCCGTTTTTCATCTACCCGACTGCCAGGCAAACCATTAGTGGATATTAATGGTAA
GCCCATGATTGTTCATGTCCTGGAGCGGGCGCGCGAATCTGGCGCGGAACGCATTATTGTCGCGACCGATCATGAAGACG
TGGCTCGTGCGGTAGAAGCGGCTGGCGGCGAAGTGTGCATGACGCGCGCCGATCACCAGTCCGGCACCGAACGGTTGGCG
GAAGTGGTAGAGAAGTGCGGATTCAGCGACGATACCGTTATTGTGAACGTTCAGGGCGATGAGCCGATGATCCCGGCGGT
TATTATTCGCCAGGTCGCGGAAAATCTGGCGCAGCGCCAGGTTGGCATGGCGACGCTGGCGGTGCCGATTCACAGCGCCG
AAGAAGCGTTTAACCCGAATGCGGTAAAAGTCGTGCTGGATGCTGAAGGCTATGCGCTTTACTTTTCCCGGGCGACGATT
CCCTGGGATCGCGATCGCTTTGCAAAAAGTCTGGAAACGGTAGGGGATACTTGCCTTCGTCACCTGGGCATTTATGGCTA
TCGCGCGGGGTTTATCCGCCGTTACGTGAGCTGGCAACCCAGCCCGCTGGAACATATTGAAATGCTGGAGCAACTCCGTG
TGCTGTGGTACGGCGAAAAAATTCATGTCGCCGTCGCCAAAGCGGTGCCCGGCACGGGCGTAGACACCGCCGACGACCTG
GAGCGCGTGCGCGCTGAAATGCGTTAA

Protein sequence :
MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDL
ERVRAEMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 7e-33 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-32 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-33 45