Gene Information

Name : serS (STM0963)
Accession : NP_459939.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1043792 - 1045084 bp
Length : 1293 bp
Strand : +
Note : 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA'

DNA sequence :
ATGCTCGATCCCAATCTGCTGCGTAATGAGCCAGACGCAGTCGCTGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAGCTGCGCGCTCTTGAAGAGCGTCGTAAAGTTTTGCAGGTCAACACGGAAAACCTGCAGGCGGAGCGTAATTCTC
GATCGAAATCCATCGGCCAGGCGAAAGCGCGCGGGGAAGATATCGAGCCTTTACGCCTGGAAGTGAATAAACTGGGCGAA
GAGCTGGATGCGGCGAAAGCCGAGCTGGATACCTTGCTGGCGGAGATCCGCGATATCGCACTGACCATCCCAAACCTGCC
TGCGGATGAAGTGCCGGTAGGTAAAGATGAAAACGACAACGTTGAAGTCAGCCGCTGGGGTACCCCGCGTGAGTTTGATT
TTGAAATCCGCGATCACGTCACCTTAGGGGAAATGCACTCCGGCCTCGACTTTGCCGCCGCGGTTAAGCTGACCGGCTCC
CGTTTTGTGGTGATGAAAGGACAGATTGCGCGTATGCATCGCGCATTGTCGCAGTTCATGTTGGATCTGCATACGGAACA
GCACGGCTATAGCGAAAACTACGTGCCGTATCTGGTTAACCACGACACGCTGTATGGCACCGGTCAATTGCCGAAATTCG
CAGGCGACTTGTTCCATACCCGTCCGCTGGAAGAAGAAGCAGACAGCAGCAACTATGCTTTGATCCCGACGGCGGAGGTT
CCGCTGACCAATCTGGTACGCGATGAAATCATCGACGAAGATCAGCTGCCGATTAAAATGACGGCGCATACGCCTTGTTT
CCGTTCTGAAGCAGGTTCTTATGGTCGTGATACCCGTGGCCTGATTCGTATGCATCAGTTTGACAAAGTTGAGATGGTGC
AGATCGTTCGCCCGGAAGATTCTATGGCTGCGTTGGAAGAGATGACCGGCCACGCGGAAAAAGTGCTCCAGCTACTGGGA
CTGCCGTACCGTAAAATCATTCTGTGCACTGGCGATATGGGCTTCGGCGCCTGCAAAACCTATGACCTCGAAGTCTGGGT
TCCGGCGCAGAATACCTACCGCGAGATCTCTTCCTGCTCTAACGTCTGGGACTTCCAGGCGCGTCGTATGCAGGCACGTT
GTCGCAGCAAGTCCGACAAAAAGACCCGTCTGGTCCATACCCTGAATGGTTCTGGTCTGGCGGTAGGTCGTACCCTGGTG
GCTGTGATGGAAAACTATCAGCAGGCTGATGGCCGCATTGAAGTGCCGGAAGTATTACGTCCGTACATGAACGGACTGGA
ATATATCGGCTAA

Protein sequence :
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
ELDAAKAELDTLLAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEV
PLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLG
LPYRKIILCTGDMGFGACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
AVMENYQQADGRIEVPEVLRPYMNGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-107 57