Gene Information

Name : leuS (STM0648)
Accession : NP_459640.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 709125 - 711707 bp
Length : 2583 bp
Strand : -
Note : 'leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucy

DNA sequence :
ATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCCAAAGTACAGCTTCACTGGGATGAGAAGCGCACATTTGAAGTGAC
CGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCCTATCCTTCTGGCCGACTACACATGGGCCACGTAC
GTAACTACACCATCGGCGACGTGGTTGCCCGCTACCAGCGTATGCTGGGCAAAAACGTGCTGCAGCCAATCGGCTGGGAC
GCCTTCGGCCTGCCGGCGGAAGGCGCGGCGGTGAAGAACAACACCGCGCCGGCGCCGTGGACGTACGACAACATCGCGTA
TATGAAAAACCAGCTAAAAACGCTGGGTTTTGGCTATGACTGGAGCCGTGAAATCGCGACCTGCACCCCGGAATACTACC
GTTGGGAACAGAAGTTCTTCACCGAGCTGTATAAAAAAGGCCTGGTGTACAAGAAGACTTCTGCCGTTAACTGGTGCCCG
AACGATCAGACCGTTCTCGCCAACGAACAGGTGATCGACGGCTGCTGCTGGCGCTGCGACACCAAAGTTGAGCGTAAAGA
GATCCCACAGTGGTTTATCAAAATCACCGCTTACGCAGACGAGCTGTTGCGCGATCTGGATAAGCTGGACCACTGGCCTG
ATACCGTAAAAACGATGCAGCGCAACTGGATTGGCCGCTCTGAAGGCGTGGAAATCACCTTCGATGTGAAGGGTTACGAT
AACACCCTGACCGTCTATACCACCCGTCCAGATACCTTTATGGGCGCCACTTACCTGGCGGTGGCCGCCGGTCATCCGCT
GGCGCAAAAAGCGGCGGCGAACAACGCCGAACTGGCGGCGTTCATCGACGAATGCCGTAACACCAAAGTGGCCGAAGCCG
AAATGGCGACCATGGAGAAAAAAGGCGTCGACACCGGCTATAAAGCGATTCATCCGTTAACTGGCGAAGAGATCCCGGTC
TGGGCGGCAAACTTTGTCCTGATGGAGTACGGCACTGGCGCGGTGATGGCCGTTCCGGGTCACGATCAGCGCGACTACGA
ATTTGCCTCCAAATACGGTTTGACCATCAAGCCGGTGATTCTGGCCGCCGACGGTTCCGAGCCGGATCTTTCCGAACAGG
CGCTGACCGAAAAAGGCGTGCTGTTTAACTCCGGCGAGTTCGACGGCCTGGCCTTTGAAGCGGCGTTTAACGCCATTGCC
GATAAACTGGCGGAAAAAGGCGTCGGCGAACGTAAAGTGAACTATCGTCTGCGTGACTGGGGCGTTTCCCGTCAGCGTTA
CTGGGGCGCGCCGATCCCGATGGTCACCCTGGAAGACGGCACCGTGCTGCCGACGCCGGAAGATCAACTGCCGGTTATTC
TGCCGGAAGATGTCGTCATGGACGGCATCACCAGCCCGATTAAAGCCGATCCTGAGTGGGCGAAAACCACCGTTAACGGT
ATGCCGGCGCTGCGTGAAACCGACACCTTCGACACCTTTATGGAATCGTCATGGTACTACGCGCGTTACACCTGCCCGCA
GTATCAGGAAGGAATGCTGGATTCGAAAGCGGCAAACTACTGGCTGCCGGTCGACATCTACATCGGCGGTATTGAACATG
CCATCATGCACCTGCTCTACTTCCGCTTCTTCCATAAGCTGATGCGCGATGCGGGCATGGTCACCTCTGACGAGCCGGCT
AAACAGTTGCTGTGCCAGGGCATGGTACTGGCGGATGCGTTCTATTATGTCGGCGAGAACGGCGAACGTAACTGGGTTTC
GCCAGTTGACGCTATCGTCGAGCGCGATGAAAAAGGCCGCATTGTCAAAGCAAAAGACGCAGCGGGTCATGAGCTGGTCT
ACACTGGCATGAGTAAAATGTCCAAGTCGAAAAATAACGGTATCGACCCGCAGGTAATGGTTGAACGTTATGGCGCGGAC
ACGGTACGCCTGTTTATGATGTTCGCTTCTCCGGCGGATATGACTCTGGAATGGCAGGAGTCCGGCGTAGAAGGCGCAAA
CCGCTTTATTAAACGCGTCTGGAAGCTGGTTTACGAACACACCGCTAAAGGTCCTGTCGCGGCGCTGAACGTCGATGCGC
TGAGCGAAGATCAAAAAGCGCTGCGTCGCGATGTGCATAAAACCATTGCCAAAGTGACCGATGATATCGGCCGCCGTCAG
ACGTTCAACACCGCCATTGCGGCGATCATGGAGTTGATGAACAAACTGGCGAAAGCCCCGCAGGAAGGCGAACAAGACCG
CGCACTGCTTCAGGAAGCGCTGCAGGCCGTCGTGCGTATGCTTAACCCGTTCACGCCGCACGTCTGCTTTACCTTGTGGC
AGGAGCTGGGCGGCGAAGGTGATATCGACAACGCGCCGTGGCCGGTAGCCGACGAGCAGGCAATGGTGGAAAACACCACG
CTGGTTGTCGTGCAGGTTAACGGTAAAGTTCGCGGGAAAATCACCGTACCGGTGGATGCTACCGAAGAACAGGTGCGTGA
ACGTGCAGGCCAGGAACATCTGGTGGCAAAATATCTTGATGGCGTTACCGTGCGTAAAGTGATTTACGTTCCGGGTAAAC
TCCTCAATCTGGTTGTTGGCTAA

Protein sequence :
MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYD
NTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPV
WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIA
DKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
MPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPA
KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD
TVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQ
TFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTT
LVVVQVNGKVRGKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-151 42