Gene Information

Name : STM4262 (STM4262)
Accession : NP_463127.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : ABC-type bacteriocin/lantibiotic exporter
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2274
EC number : -
Position : 4499193 - 4501259 bp
Length : 2067 bp
Strand : +
Note : similar to leukotoxin expression protein B (gi|7467272); contains an N-terminal double-glycine peptidase domain

DNA sequence : 
ATGGATAAAAAACTAGAACCTTATTATTTAAGTGCGGAAACGGCATTATCTATAGTGTCTAAAAAATTCAACATAAAAAT
TGACATCAAAGAGGATGATATAAATTTAAGATTTAAAAAGTACGACAGAAATAACACTGACGACTCTATACAAATGAAGA
ATTTCTTTTTGTCGTTAGGGCTTTCTCTACAGGATATATTATTTAATAATGGTGAGGATTTACTAAATGAGCCTATGCCG
ATTTTACTATTAACACCAGAAATGAAGTGGATGGTGTGTGTGAGTGGCGGGCAAAAAATAAAGTTGGTAAACGCGCGCGG
TGAACTCTGTTATGTTGAAATTGAAGATGAATATTTAAAAGAGTTATCTGCATTTAGTATACTACCTTTAAATAAAGTTG
TTGATAGTATAAGAGTAAAAAATATCATAAAAAACTCTTTATCGATGAACAAGATTTTTTATACTAAATACTTTTTTTCA
TCTCTTTTTATGGCAATTTTTGCGTTAACTATCCCAGTATTTAGTAATCTGTTCTATGATAAGCTTGTTCCAAGCGCTTC
GGTTTCATCTTTATTTGGCGTGGCTATAATTGTTGCTGTATTTATTGTTTTTGAGTTTATCCTTCGTACTTCGAAAGATA
TTTATCAGTCTATCACAGCAAGGCAGGATGACGTCGATATTGATATCGCATTTCTTGAAGCGGTACTTTATAGTAAAAAG
AAAAATGGCAGATCCATGTCATCAGCATTTGTGCTATGGAATGAGTTTCAGAAAATTAAACCCGTTTTATTAAACTCGAT
CTTTCAACGTATAGCCGATATTCCAATATTTATTATATTTCTCATTGTTATATATGTAAATTTAGGTCTGGTTGTTATTG
TACCTATTACCATGTTTATCGTCTCTATTATTATTTCCCTCGTTAACCACCATTATACTAATGAGTTAATGAACAAACAA
AAAGAAGGACAGAAGAACAGGAATATTTTTATCTCAGAAGTTTTCTTATCTATTAAAATGATCCATACCTTAAATAATCA
AGGTTTACTTTTTGATTGGGTTAATACATCAAATGAACAGTCGTATCTTAACCTGAAGATAAGGAAATTAAATCTTATCT
ATCAATCTATATTGGGGAGTATGTCATCTATTACCCAAATAACTATTATGGTAATAGCCTTTTTTATGGTAATCAAGGGT
GATGTTACTACTGGCGCAATTGTTTCATCTGTCATTGTCTCTGGCCGTATTTCCGGGATCATTTCGAATTTTTCTTCTAC
ATTAATCTCTATTTTATCAGCAGAAAAAACCGGTAAGGATCTGCTTTCTTTTTTTGATGAAGATCAGGCAGAAAAAACAC
CGGCATTACAGTCAATATCAAAGTGCAATGGCGATATCTCTATCCGGGGCGTGAGTTATCAGTATGATGCTCAATCTCCG
ATGATTATTAACCGACTGTCTATAGACATACCTGCGGGGCAACGTGTCGCGGTGGTAGGCGAATGCGGAGCAGGAAAAAG
CTCATTACTGGGAATGCTATCTGGCTACCTTTCGCCAACAGACGGTGCCATTTTATATGATGGATATAACTTAGGACATT
TATCGCAGAACTTTTTTTCTCAGCATTTAAGCGTGGTGACGACACATGATGTTTTATTCACCGGAACCATTGAAAGTAAT
TTCGCGTTAAAACCGCAAAACGACAGGGGCCGGGTACTCAAGGCGCTTCAGCTGGCGAACTGTGGTTTTATCTTGCAACA
TCCTATGGGGCTGAAGTTTCCGGTGAATTTTATGGCTAAAAACCTGTCATCCGGACAGCAGCAGCAGTTATTATTAGCAC
GTAGTCTGAGTAGTGACGCCAGCGTCTTTTTATGGGATGAACCAACATCAAATCTGGATGAGAATACCGAGAAGCAAATT
TTTGATAACTTAGATGAGTTTATTCATGGGAAAACGTTGATCATGGTGACGCATCGTCGATATCTGATAAAGTATTTTGA
CCGGGTCCTGGTAATGAAAGGTGGAAAAATAATCCGTGATTGTTCTCCGGATAAATTATTAATGTAA

Protein sequence : 
MDKKLEPYYLSAETALSIVSKKFNIKIDIKEDDINLRFKKYDRNNTDDSIQMKNFFLSLGLSLQDILFNNGEDLLNEPMP
ILLLTPEMKWMVCVSGGQKIKLVNARGELCYVEIEDEYLKELSAFSILPLNKVVDSIRVKNIIKNSLSMNKIFYTKYFFS
SLFMAIFALTIPVFSNLFYDKLVPSASVSSLFGVAIIVAVFIVFEFILRTSKDIYQSITARQDDVDIDIAFLEAVLYSKK
KNGRSMSSAFVLWNEFQKIKPVLLNSIFQRIADIPIFIIFLIVIYVNLGLVVIVPITMFIVSIIISLVNHHYTNELMNKQ
KEGQKNRNIFISEVFLSIKMIHTLNNQGLLFDWVNTSNEQSYLNLKIRKLNLIYQSILGSMSSITQITIMVIAFFMVIKG
DVTTGAIVSSVIVSGRISGIISNFSSTLISILSAEKTGKDLLSFFDEDQAEKTPALQSISKCNGDISIRGVSYQYDAQSP
MIINRLSIDIPAGQRVAVVGECGAGKSSLLGMLSGYLSPTDGAILYDGYNLGHLSQNFFSQHLSVVTTHDVLFTGTIESN
FALKPQNDRGRVLKALQLANCGFILQHPMGLKFPVNFMAKNLSSGQQQQLLLARSLSSDASVFLWDEPTSNLDENTEKQI
FDNLDEFIHGKTLIMVTHRRYLIKYFDRVLVMKGGKIIRDCSPDKLLM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STM4262 NP_463127.1 ABC-type bacteriocin/lantibiotic exporter Not tested SPI-4 Protein 0.0 100
spi4_R AAC26655.1 ltkB homolog Virulence SPI-4 Protein 0.0 100
siiF CAE11798.1 putative type-I secretion protein (putative inner membrane component) Virulence SPI-4 Protein 0.0 100
STY4460 NP_458560.1 putative type-1 secretion protein Not tested SPI-4 Protein 0.0 99
SC4141 YP_219128.1 bacteriocin/lantibiotic ABC transporter Not tested SPI-4 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STM4262 NP_463127.1 ABC-type bacteriocin/lantibiotic exporter VFG0582 Protein 0.0 100