Gene Information

Name : STM4260 (STM4260)
Accession : NP_463125.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : cation efflux pump
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0845
EC number : -
Position : 4481180 - 4482457 bp
Length : 1278 bp
Strand : +
Note : membrane permease; HlyD secretion protein (gi|7467244)

DNA sequence :
ATGAATAGAAGACAAAGCGATCATCTCATGATGATAATTATTTCTTTGACGATCTTAATTATTATCCTTACCTACTTTAT
AGAAATTAATTCAGTGGTTCATGGTCAGGGCGTTATCACTACTAAAGATAATGCTCAGTTAATATCTCTTTCTAAAGGAG
GGACGATACAAGATATTTATGTAGCCGAGGGTGATACTGTAAAAAAAGGAGAACTCCTTGCAAAGGTCGTTAACCTTGAT
CTGCAAAAAGAATATCAAAGGTATAGAACTCAAAAAGGGTATCTGGATAAAGATGTTAACGAAATATCTTTCATTCTTGA
TAAAGAAAATGAGAGTGGGTTGATTACCCTGGATGGCACCCGTTCTTTAAGCAATAAAGAGGTAAAAGCGAATATTGAAT
TAGTGCATAGTCAGATAAGAGCTAAAGAGTTAAAAAAAACCTCTCTTGATTCTGAGATTAGCGGATTACAAGAGAAGCTG
AGTTCGAAAGAAAAAGAACTCGCATTGCTTGCCGAAGAAATAAATATTCTTTCCCCACTGGTAAAAAAAGGAATTAGCCC
ATATACCAATTTTCTTAACAAGAAACAGGCGTATATAAAAGTTAAGTCTGAAATTAATGATATTGAAAGTAGCATCACTT
TAAAAAAAGATGATATTGAGTTGGTTGTTAATGATATTGAGGCGCTTAATAATGAATTGCGACTATCTTTATCTAAAATA
ATATCTAAAAATCTTCAGGAACTTGAGGTTGTTAACTCTACATTAAAAGTAATAGAGAAGCAGATAAATGAGGAGGATAT
CTATTCACCGGTTGACGGTGTAATTTATAAAATCAATAAAAGTGCCACTACTCATGGTGGTGTGATTCAGGCGGCGGACT
TACTTTTTGAAATAAAACCAAAAGTAAGGACTATGCTGGCCGATGTGAAAATATTACCCAAATACCGTGACCAAATATAT
GTAGATGAAGCCGTTAAACTGGATGTGCAGTCAATTATCCAACCAAAGATAAAATCGTATAATGCGACTATCGATAATAT
TAGCCCTGATTCCTATGAGGAAAATACCGGAGGAACAATTCAGCGTTATTATAAAGTAATTATTGCATTCGATGTTAATG
AAGATGATTTACGGTGGTTAAAACCAGGTATGACTGTTGACGCCAGTGTAATTACCGGAAAACACAGCATTATGGAATAC
CTGTTATCTCCCTTGATGAAAGGCGTGGACAAAGCCTTTTCAGAACCAGTTAATACTAAACGATTAGATACACCTTGA

Protein sequence :
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVKKGELLAKVVNLD
LQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKL
SSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKPKVRTMLADVKILPKYRDQIY
VDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEY
LLSPLMKGVDKAFSEPVNTKRLDTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spi4_D AAC26642.1 HLYD family secretion protein Virulence SPI-4 Protein 1e-175 100
siiD CAE11796.1 putative type-I secretion protein, putative inner membrane component Virulence SPI-4 Protein 1e-175 100
SC4139 YP_219126.1 membrane permease, cation efflux pump Not tested SPI-4 Protein 2e-175 100
STM4260 NP_463125.1 cation efflux pump Not tested SPI-4 Protein 2e-175 100
STY4457 NP_458557.1 putative type-I secretion protein Not tested SPI-4 Protein 9e-175 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STM4260 NP_463125.1 cation efflux pump VFG0580 Protein 8e-176 100