Gene Information

Name : alr (STM4247)
Accession : NP_463112.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 4468038 - 4469117 bp
Length : 1080 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCAAGCGGCAACAGTCGTCATTAACCGCCGCGCTCTGCGACACAACCTGCAACGTCTGCGTGAACTGGCGCCTGCCAG
TAAGCTGGTTGCGGTGGTGAAAGCGAACGCTTATGGACACGGTCTTCTGGAGACCGCGCGAACGCTCCCTGATGCTGACG
CTTTTGGCGTGGCGCGTCTTGAAGAGGCTCTACGTCTGCGAGCGGGCGGGATCACGCAGCCAATCCTGCTGCTGGAGGGT
TTTTTCGACGCCGCCGATTTGCCGACCATTTCCGCGCAATGTCTGCATACCGCCGTACATAATCAAGAGCAGCTTGCCGC
CCTGGAGGCGGTGGAGCTGGCGGAGCCGGTAACGGTCTGGATGAAGCTGGATACCGGTATGCATCGTCTCGGCGTGCGTC
CCGAAGAGGCGGAGGCGTTCTACCAGCGTCTGACGCACTGTAAAAATGTACGCCAGCCGGTGAATATCGTCAGCCATTTT
GCCCGTGCGGATGAGCCGGAATGCGGCGCTACCGAACATCAGCTCGACATTTTTAATGCCTTCTGTCAGGGTAAACCCGG
TCAGCGCTCTATTGCCGCGTCTGGCGGTATCCTGCTGTGGCCGCAGTCTCACTTTGACTGGGCGCGTCCGGGCATCATTT
TGTATGGCGTATCGCCGCTGGAGCACAAACCCTGGGGGCCGGATTTTGGTTTTCAGCCGGTGATGTCCTTAACCTCCAGT
TTGATCGCGGTGCGTGACCACAAAGCGGGCGAACCGGTGGGCTACGGCGGGACATGGGTGAGTGAGCGCGACACGCGCCT
GGGCGTGGTGGCGATGGGTTATGGCGATGGCTACCCACGAGCGGCGCCTTCCGGTACGCCAGTACTGGTCAATGGTCGTG
AAGTTCCGATTGTCGGGCGGGTGGCGATGGATATGATTTGCGTAGATTTGGGGCCAAACGCGCAGGATAACGCGGGCGAT
CCGGTGGTCTTATGGGGTGAAGGTCTGCCGGTTGAACGTATCGCTGAAATGACAAAAGTAAGTGCTTACGAACTTATCAC
GCGCCTGACCTCAAGGGTGGCGATGAAGTATATTGATTAA

Protein sequence :
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITQPILLLEG
FFDAADLPTISAQCLHTAVHNQEQLAALEAVELAEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLTHCKNVRQPVNIVSHF
ARADEPECGATEHQLDIFNAFCQGKPGQRSIAASGGILLWPQSHFDWARPGIILYGVSPLEHKPWGPDFGFQPVMSLTSS
LIAVRDHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPNAQDNAGD
PVVLWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 3e-54 42