Gene Information

Name : thiC (STM4164)
Accession : NP_463033.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4380491 - 4382386 bp
Length : 1896 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGCACCGCGTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGCGAAATTCAACTTAGCCCCA
CGCTCATCGGCGGCAGTAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTACCGGTATACGACACCTCCGGCCCCTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCATGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTATACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGTTTTACCG
GCCTGCTGACGCCAAAACGCGCTAAAGCGGGCAAGCGCGTCACCCAGTTACACTACGCCCGCAAGGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAATATGGGCCGTGAGCGCATTCGCAGTGAAGTGCTGCGCCACCAGCATCCGGG
GATGAACTTTGGCGCGCGCCTGCCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTCGCCGCGGGCCGCGCGATTA
TTCCCGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATCGGCCGCAACTTCCTGGTCAAAGTGAATGCCAACATC
GGTAACTCGGCGGTCACCTCCTCCATCGAAGAAGAGGTGGAAAAACTGGTGTGGTCAACCCGCTGGGGCGCGGACACGGT
GATGGACCTCTCCACCGGTCGCTATATTCATGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCGGCACCG
TCCCGATCTACCAGGCGCTGGAGAAGGTCAACGGGATCGCCGAAGATCTTACCTGGGAAGCGTTCCGCGACACGCTACTG
GAGCAGGCTGAACAGGGCGTCGACTACTTCACCATTCACGCGGGCGTGCTGCTGCGCTACGTGCCAATGACCGCCAAACG
CCTGACCGGGATTGTCTCACGCGGCGGTTCCATCATGGCAAAGTGGTGTCTCTCCCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATTTGTGAAATTTGCGCCGCCTACGACGTCTCCTTGTCGCTGGGCGACGGCCTGCGCCCCGGCTCC
ATTCAGGATGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAATTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGCCACGTACCCATGCATATGATCCAGCGCAACATGACCGAAGAGCTGGAGAGCT
GCCATGAAGCACCGTTCTACACCTTAGGGCCATTGACCACCGATATCGCGCCGGGCTATGACCACTTCACCTCCGGGATC
GGTGCCGCGATGATCGGCTGGTTTGGCTGCGCGATGCTGTGTTATGTGACGCCGAAAGAACACCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTAATCACCTACAAAATCGCCGCCCACGCCGCGGATTTAGCCAAAGGACATCCGGGCGCGC
AGATCCGCGATAACGCCATGTCGAAAGCGCGCTTTGAATTCCGCTGGGAAGATCAGTTTAACCTCGCGCTCGACCCGTTC
ACCGCCCGCGCTTATCACGATGAAACCCTGCCGCAGGAGTCCGGCAAGGTTGCCCACTTCTGCTCCATGTGCGGGCCGAA
GTTCTGCTCGATGAAAATCAGCCAGGAGGTCCGCGACTACGCCGCCGCACAAACTATTGAAATCGGCATGGCGGATATGT
CAGAGGACTTCCGCGCCAAAGGCGGCGAAATTTATCTCAAGCGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARKGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEIGMADMSEDFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70