Gene Information

Name : glnA (STM4007)
Accession : NP_462887.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 4215599 - 4217008 bp
Length : 1410 bp
Strand : -
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGTCCGCTGAACACGTTTTGACGATGCTGAACGAGCACGAAGTGAAGTTTGTCGATCTGCGCTTCACCGATACCAAAGG
CAAAGAACAGCACGTCACGATTCCTGCTCATCAGGTAAATGCCGAATTCTTTGAAGAAGGCAAAATGTTTGACGGCTCCT
CTATCGGCGGCTGGAAAGGCATTAACGAATCCGACATGGTGCTGATGCCCGATGCGTCCACTGCGGTTATCGACCCGTTC
TTCGCGGACTCCACCCTGATTATCCGTTGTGACATCCTGGAGCCTGGCACTCTGCAAGGTTATGACCGTGACCCACGTTC
CATCGCAAAACGTGCGGAAGACTACCTGCGCGCGACCGGTATCGCCGATACCGTCCTGTTTGGGCCGGAACCTGAATTCT
TCCTGTTCGACGACATCCGCTTCGGCGCATCTATCTCCGGCTCACATGTGGCGATTGACGATATTGAAGGCGCCTGGAAC
TCCTCTACCAAGTACGAAGGCGGCAACAAAGGCCATCGTCCGGGCGTGAAAGGCGGTTATTTCCCGGTTCCGCCAGTTGA
CTCCGCGCAGGATATCCGTTCTGAAATGTGTCTGGTCATGGAGCAGATGGGCCTGGTCGTTGAAGCGCACCACCACGAAG
TAGCGACCGCAGGTCAGAACGAAGTGGCGACCCGCTTTAACACCATGACCAAAAAAGCCGACGAAATTCAGATTTACAAA
TATGTCGTGCATAACGTGGCTCACCGCTTCGGTAAGACCGCGACCTTTATGCCAAAACCGATGTTCGGCGATAACGGTTC
CGGTATGCACTGCCACATGTCTCTGGCGAAGAACGGCACCAACCTGTTCTCTGGCGACAAATATGCCGGCCTGTCTGAAC
AAGCGCTGTACTACATCGGCGGCGTCATCAAACACGCCAAAGCCATCAACGCCCTGGCGAACCCGACCACCAACTCCTAC
AAGCGTCTGGTCCCGGGTTACGAAGCGCCGGTGATGCTGGCCTACTCCGCCCGTAACCGTTCCGCCTCCATCCGTATTCC
GGTGGTGGCGTCTCCGAAAGCGCGCCGTATCGAAGTTCGCTTCCCGGACCCGGCGGCTAACCCGTATCTGTGCTTTGCCG
CCCTGCTGATGGCCGGTCTGGACGGGATTAAGAATAAGATTCACCCGGGCGAAGCCATGGACAAAAACCTGTATGACCTG
CCGCCGGAAGAAGCGAAAGAGATCCCACAGGTAGCGGGTTCTCTGGAAGAAGCGCTGAACGCGCTGGACCTGGACCGCGA
GTTCCTGAAAGCAGGCGGCGTGTTCACTGATGAAGCGATCGATGCGTATATTGCGCTGCGTCGCGAAGAAGATGACCGCG
TGCGTATGACCCCGCACCCGGTAGAGTTTGAGCTGTACTACAGCGTTTAA

Protein sequence :
MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPF
FADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWN
SSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSY
KRLVPGYEAPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDL
PPEEAKEIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 6e-103 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA NP_462887.1 glutamine synthetase VFG1399 Protein 4e-116 51