Gene Information

Name : aldB (STM3680)
Accession : NP_462580.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.22
Position : 3867973 - 3869511 bp
Length : 1539 bp
Strand : -
Note : similar to Escherichia coli aldehyde dehydrogenase B; lactaldehyde dehydrogenase (AAC76612.1)

DNA sequence : 
ATGACGAACAATCCCCCTTCAACACGTATTCAGCCAGGTGAATACGGGTACCCACTGAAGTTAAAAGCCCGCTATGACAA
TTTTATTGGTGGTGACTGGGTTGCGCCCGCCGACGGCGAATATTATCAAAACCTGACGCCAGTGACCGGCCAGCCGCTAT
GTGAAGTCGCTTCCTCCGGTAAAAAAGATATCGATTTAGCGCTCGACGCCGCGCATAAGGCGAAAGATAAGTGGGCGCAT
ACGTCAGTACAAGACCGTGCCGCTATCTTGTTTAAGATCGCCGATCGGATGGAACAAAACCTCGAACTGTTGGCGACAGC
GGAAACCTGGGATAACGGTAAACCGATTCGTGAAACCAGCGCCGCCGACGTACCGCTGGCGATCGATCATTTCCGCTATT
TCGCCTCCTGTATACGTGCGCAGGAGGGCGGGATTAGCGAAGTTGATAGCGAAACCGTGGCCTACCATTTTCACGAACCG
CTTGGCGTCGTGGGGCAGATAATCCCGTGGAACTTTCCGTTGTTGATGGCAAGCTGGAAAATGGCGCCAGCGCTGGCGGC
GGGTAACTGCGTGGTGCTTAAACCGGCACGCCTGACGCCGCTTTCCGTTTTGCTGTTGATGGAAATCATTGGCGATCTGT
TACCGCCGGGCGTCGTCAACGTCGTGAACGGCGCGGGCGGCGAGATTGGCGAATATCTGGCGACCTCGAAACGTATCGCG
AAGGTGGCGTTTACCGGTTCGACGGAAGTGGGTCAACAGATCATGCAGTACGCCACGCAGAACATTATTCCGGTGACGCT
GGAGTTAGGCGGTAAATCGCCCAATATCTTCTTTGCTGACGTGATGGATGAGGAAGATGCGTTCTTTGATAAAGCGCTGG
AGGGATTTGCCCTGTTTGCCTTTAACCAGGGCGAGGTGTGTACCTGTCCAAGCCGTGCGCTGGTCCAGGAGTCCATCTAT
GAGCGCTTTATGGAACGCGCTATTCGCCGGGTGGAGAGCATTCGCAGCGGGAACCCGCTAGATAGCGGTACACAGATGGG
GGCGCAGGTCTCCCACGGCCAGCTTGAGACTATCCTCAATTATATCGATATCGGTAAAAAAGAGGGGGCCGATATTCTGA
CCGGTGGGCGACGCAAGGAGCTGGATGGCGAACTTAAAGAGGGCTATTACCTTGAGCCTACCATTCTGTTTGGTAAGAAC
AATATGCGCGTCTTTCAGGAGGAGATCTTTGGCCCAGTGCTGGCGGTAACCACCTTTAAAACCATGGAGGAGGCGCTGGA
AATCGCTAACGATACGCAGTATGGCCTCGGCGCCGGCGTCTGGAGCCGCAACGGCAATCTGGCCTATAAGATGGGGCGCG
GCATTCAGGCCGGGCGCGTATGGACCAACTGCTATCACGCCTATCCGGCACATGCTGCGTTCGGCGGCTATAAGCAGTCG
GGCATCGGGCGCGAAACGCATAAGATGATGCTGGAACACTACCAGCAAACCAAGTGCCTGCTGGTGAGCTATTCCGATAA
GCCTCTGGGGCTGTTCTGA

Protein sequence : 
MTNNPPSTRIQPGEYGYPLKLKARYDNFIGGDWVAPADGEYYQNLTPVTGQPLCEVASSGKKDIDLALDAAHKAKDKWAH
TSVQDRAAILFKIADRMEQNLELLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIIGDLLPPGVVNVVNGAGGEIGEYLATSKRIA
KVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNIFFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIY
ERFMERAIRRVESIRSGNPLDSGTQMGAQVSHGQLETILNYIDIGKKEGADILTGGRRKELDGELKEGYYLEPTILFGKN
NMRVFQEEIFGPVLAVTTFKTMEEALEIANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTNCYHAYPAHAAFGGYKQS
GIGRETHKMMLEHYQQTKCLLVSYSDKPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-140 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-145 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-145 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-145 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-145 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-54 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB NP_462580.1 aldehyde dehydrogenase B VFG0082 Protein 1e-140 64