Gene Information

Name : lpfC (STM3638)
Accession : NP_462539.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : long polar fimbrial outer membrane usher protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 3824115 - 3826643 bp
Length : 2529 bp
Strand : -
Note : outer membrane usher protein LpfC precursor (SW:LPFC_SALTY)

DNA sequence :
ATGACATGGACGCATCTTCCTCTGGGCAATAAGACCTCGCGTTTCACGCAGTCTGCGCTTGCGCTGATGATAGCGGGTAC
GCTCCCCGCGTATGCGGGAACATTTAACCCGCGCTTTCTGGAGGATGTGCCGGGTATTGATCAGCACGTTGACCTTTCAA
TGTATGAATCCAATAAAGCTGAACACCTGCCAGGTAAATACCGCGTCTCGGTGGTGGTCAACGAAAAAAAAATGGAGTCT
CGCACCCTGGAGTTTAAGGCAGCGACAGAGGCGCAGCGCGCAAAAATGGGTGAATCCCTGGTGCCGTGCTTAAGCCGCGT
GCAGCTTGAAGATATGGGCGTGCGTATTGATAGCTTCCCGGCGCTGAAAATGGCCCCGCCTGAAGCCTGTGTTGCTTTTG
ACGACATTATTCCCCAGGCCGCCAGCCATTTCGACTTTGCAGACCAGACCCTGATCATGAGCTTCCCGCAGGCTGCGATG
AAGCAGACAGCGCGCGGTACGGTGCCAGAATCGCAGTGGGACGAAGGGGTGAATGCCCTGCTGGTGGATTATAACTTTTC
CGGCAGCAACGCCAGCTATGACGCACACGACAGTGAAACCAGCTACAACAGCGACAGCTACTATCTGAATCTGCGCAGCG
GTATGAACCTGGGGGCATGGCGGTTACGTAACTATAGCACCTGGACGCGAAACGACGGTAACAACACATGGGATAACATT
GGCACATCCTTAAGCCGTGCCATTGTACCGCTGAAATCACAGCTGACGTTGGGGGATACCTCCACTGCCGGTGATATTTT
TGACAGCGTTCAGATGCGCGGTGTGCAGTTAACTTCCGACGAAGAGATGCTGCCTGACAGCCAGCGCGGGTTTGCGCCCG
TCATCCGGGGTATTGCCAAAAGTAACGCCGAAGTTACCGTTGAGCAGAACAACTACGTTATTTACCGTACGTTTGTTCAG
CCGGGTGCGTTTGAAATTAACGACCTGTATCCAACCTCAAACAGCGGCGACCTGACGGTCACCATTAAAGAATCGGACGG
CAGTGAGCAGAAGTTCGTTCAGCCGTTCTCCTCGGTGGCGCTCCTCCAGCGTGAAGGCCATCTCAAATACAGCCTTTCCG
CCGGGGAATACCGTGCCGGGAACTATAACAGCGCCGAGCCGAAATTCGGGCAGCTTGATGCCATGTACGGCCTGCCGTAT
GGCTTTACCGTTTACGGTGGTGCGATCTTCTCTGACGACTATTACTCGCTGGCGGGAGGATTAGGTAAAAACTTCGGTTA
TATCGGCGCGATCTCCATCGATGTAACCCAGGCAAAAAGCAAGCTGGCAAATGAGGAGAATTCGGAAGGTCAGTCTTATC
GTTTCCTCTACTCCAAGAGCTTTAACAGCGGTACAGATTTCCGTCTGCTGGGTTACAAGTATTCGACCAGCGGCTATTAC
ACCTTCCAGGAAGCGACGGATGTGCGCAGCGATGCGGACAGCTCTTATAGCCAGTACCACAAACGTAGTCAGATTCAGGG
CAACGTGACGCAGCAACTGGGCGCCTGGGGCTCGGTCTATTTTAACGTCACGCAGCAGGACTACTGGAACGATGAAGGTA
AACAGCGTTCGCTGAATGCCGGTTATAACGGCCGTATTGGCCGCGTGAACTACAGCGTTGCTTACACCTGGACGAAAAGC
CCGGAGTGGGATGAGAGCGATCGTTTACTGTCATTCTCCATGTCGATTCCACTGGGACGCGTGTGGAGTAACTACCACCT
CACGACCGATCAGCATGGCCGAACCAACCAGCAGTTAGGGGTGAGCGGCACCGCGCTGGAAGACCACAACCTGAACTATA
GTGTGCAGGAAGGCTACGGCAGCAACGGCGTGGGTAACAGCGGCAGCGTGAACCTGGATTACCAGGGCGGCGTGGGTAGC
GCCAGCCTGGGTTACAACTACAACCGTGACGGCCAGCAGGTGAACTACGGTTTGCGCGGCGGTGTGATAGCCCATAGCGA
AGGTATCACTCTTTCTCAACCGCTGGGTGAATCCATGGCCATTATCTCCGCGCCGGGCGCGCGCGGCGCGCACGTGATCA
ACAACGGTGGTGTGGAAGTGGACTGGATGGGTAATGCGGTCGTACCTTACCTTACTCCGTACCGTGAAACGGAAGTCTCA
CTGCGAAGCGACAGCCTGAACAACCAGGTTGACCTGGATACCGCCTCCGTCAACGTAGTGCCGACACGCGGCGCGATTGT
TCGTGCCCGCTTCGATACCCGAGTGGGCTATCGTGTGCTGATGAATCTGACGCAGGCCAATGGCAAAGCGGTGCCGTTTG
GTGCTACCGCCACGCTGCTGGATACCACAAAAGAGTCCAGCAGCATTGTGGGTGAAGACGGTCAGCTTTATATCAGCGGG
ATGCCGGAGAAAGGTGCCCTTCAGGTGAACTGGGGTAAAGACCAGGCACAGCAATGCCGCGTGGCGTTTACGCTGCCGGA
ACAACAGGATAATACCGGCGTGGTGATGGCGAATGCCGTCTGCCGGTAA

Protein sequence :
MTWTHLPLGNKTSRFTQSALALMIAGTLPAYAGTFNPRFLEDVPGIDQHVDLSMYESNKAEHLPGKYRVSVVVNEKKMES
RTLEFKAATEAQRAKMGESLVPCLSRVQLEDMGVRIDSFPALKMAPPEACVAFDDIIPQAASHFDFADQTLIMSFPQAAM
KQTARGTVPESQWDEGVNALLVDYNFSGSNASYDAHDSETSYNSDSYYLNLRSGMNLGAWRLRNYSTWTRNDGNNTWDNI
GTSLSRAIVPLKSQLTLGDTSTAGDIFDSVQMRGVQLTSDEEMLPDSQRGFAPVIRGIAKSNAEVTVEQNNYVIYRTFVQ
PGAFEINDLYPTSNSGDLTVTIKESDGSEQKFVQPFSSVALLQREGHLKYSLSAGEYRAGNYNSAEPKFGQLDAMYGLPY
GFTVYGGAIFSDDYYSLAGGLGKNFGYIGAISIDVTQAKSKLANEENSEGQSYRFLYSKSFNSGTDFRLLGYKYSTSGYY
TFQEATDVRSDADSSYSQYHKRSQIQGNVTQQLGAWGSVYFNVTQQDYWNDEGKQRSLNAGYNGRIGRVNYSVAYTWTKS
PEWDESDRLLSFSMSIPLGRVWSNYHLTTDQHGRTNQQLGVSGTALEDHNLNYSVQEGYGSNGVGNSGSVNLDYQGGVGS
ASLGYNYNRDGQQVNYGLRGGVIAHSEGITLSQPLGESMAIISAPGARGAHVINNGGVEVDWMGNAVVPYLTPYRETEVS
LRSDSLNNQVDLDTASVNVVPTRGAIVRARFDTRVGYRVLMNLTQANGKAVPFGATATLLDTTKESSSIVGEDGQLYISG
MPEKGALQVNWGKDQAQQCRVAFTLPEQQDNTGVVMANAVCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 7e-166 45
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 9e-168 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpfC NP_462539.1 long polar fimbrial outer membrane usher protein VFG0454 Protein 0.0 100
lpfC NP_462539.1 long polar fimbrial outer membrane usher protein VFG0876 Protein 2e-168 45
lpfC NP_462539.1 long polar fimbrial outer membrane usher protein VFG1645 Protein 5e-168 41
lpfC NP_462539.1 long polar fimbrial outer membrane usher protein VFG0446 Protein 1e-153 41
lpfC NP_462539.1 long polar fimbrial outer membrane usher protein VFG0912 Protein 3e-167 41