Gene Information

Name : sipC (STM2884)
Accession : NP_461805.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : translocation machinery component
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3027857 - 3029086 bp
Length : 1230 bp
Strand : -
Note : cell invasion protein SspC (gi|7443298); involved in translocating secreted proteins to host cell; translocon; type III secretion; inserted into host cell plasma membrane; interacts with SipC

DNA sequence :
ATGTTAATTAGTAATGTGGGAATAAATCCCGCCGCTTATTTAAATAATCATTCTGTTGAGAATAGTTCACAGACAGCTTC
GCAATCCGTTAGCGCTAAAGATATTCTGAATAGTATTGGTATTAGCAGCAGTAAAGTCAGTGACCTGGGGTTGAGTCCTA
CACTGAGCGCGCCTGCGCCAGGGGTATTAACGCAAACCCCCGGAACGATCACGTCCTTTTTAAAAGCCAGTATTCAAAAT
ACCGACATGAATCAGGATTTGAATGCTCTGGCAAATAATGTCACGACTAAAGCGAATGAGGTTGTGCAAACCCAGTTACG
CGAGCAGCAGGCAGAAGTCGGAAAGTTTTTTGATATTAGCGGAATGTCTTCCAGTGCCGTTGCGCTGTTGGCTGCCGCGA
ATACGTTAATGCTGACGTTGAACCAGGCTGATAGCAAACTGTCTGGTAAGTTGTCATTAGTCAGTTTTGATGCAGCTAAA
ACGACGGCAAGCTCCATGATGCGCGAAGGGATGAATGCGTTGTCCGGTAGTATTTCCCAGAGCGCGCTTCAGTTGGGGAT
CACTGGCGTGGGCGCCAAACTGGAATATAAGGGGCTGCAGAATGAAAGAGGCGCGCTTAAACATAATGCCGCGAAGATCG
ATAAACTGACCACTGAAAGCCACAGTATTAAAAACGTGCTGAACGGGCAGAATAGCGTCAAACTCGGTGCTGAAGGCGTC
GATTCTCTGAAATCGTTAAATATGAAGAAAACCGGTACCGATGCGACGAAAAATCTTAATGATGCGACGCTTAAATCTAA
TGCCGGAACCAGCGCCACGGAAAGTCTGGGTATTAAAGACAGTAATAAACAAATCTCCCCTGAACATCAGGCTATTCTGT
CGAAACGTCTTGAGTCTGTCGAATCCGATATTCGTCTTGAGCAGAATACCATGGATATGACCCGAATCGATGCGCGCAAG
ATGCAGATGACGGGCGATCTGATTATGAAGAACTCGGTCACGGTCGGTGGTATTGCAGGGGCGTCCGGGCAGTACGCCGC
TACTCAGGAACGTTCCGAGCAGCAAATTAGCCAGGTGAATAACCGGGTTGCCAGCACCGCATCGGACGAAGCCCGTGAAA
GTTCACGTAAATCGACCAGCCTGATTCAGGAAATGCTGAAAACAATGGAGAGCATTAACCAGTCGAAAGCATCCGCACTC
GCTGCTATCGCAGGCAATATTCGCGCTTAA

Protein sequence :
MLISNVGINPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSSKVSDLGLSPTLSAPAPGVLTQTPGTITSFLKASIQN
TDMNQDLNALANNVTTKANEVVQTQLREQQAEVGKFFDISGMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAK
TTASSMMREGMNALSGSISQSALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTTESHSIKNVLNGQNSVKLGAEGV
DSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESLGIKDSNKQISPEHQAILSKRLESVESDIRLEQNTMDMTRIDARK
MQMTGDLIMKNSVTVGGIAGASGQYAATQERSEQQISQVNNRVASTASDEARESSRKSTSLIQEMLKTMESINQSKASAL
AAIAGNIRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipC YP_217803.1 cell invasion protein Virulence SPI-1 Protein 7e-174 100
sipC NP_461805.1 translocation machinery component Virulence SPI-1 Protein 7e-174 100
sipC NP_457278.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 1e-172 99
sipC NP_806487.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 1e-172 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sipC NP_461805.1 translocation machinery component VFG0545 Protein 3e-174 100