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Name : sptP (STM2878) Accession : NP_461799.1 Strain : Salmonella enterica LT2 Genome accession: NC_003197 Putative virulence/resistance : Virulence Product : protein tyrosine phosphatase/GTPase activating protein Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG2453 EC number : - Position : 3022071 - 3023702 bp Length : 1632 bp Strand : - Note : protein tyrosine phosphatase SptP (gi|1519054); translocated protein; type III secretion; antagonizes bacterial-encoded exchange factors SopE and SopE2 by interfering with stimulation of Cdc42 and Rac1; binds Rac1 DNA sequence : ATGCTAAAGTATGAGGAGAGAAAATTGAATAATTTAACGTTGTCTTCGTTTTCAAAAGTTGGTGTGTCGAATGATGCCCG ACTTTATATTGCTAAGGAAAATACTGATAAGGCATATGTTGCGCCTGAAAAATTTTCGTCAAAAGTATTAACCTGGCTTG GAAAAATGCCGTTATTTAAAAACACTGAAGTGGTGCAAAAACATACGGAAAATATCAGAGTACAGGACCAAAAGATTTTA CAGACATTTCTCCATGCACTAACGGAAAAATATGGGGAAACAGCGGTTAATGACGCACTGTTAATGTCCCGTATAAATAT GAACAAACCCCTTACCCAACGTTTAGCAGTGCAGATCACGGAGTGTGTAAAAGCTGCTGACGAAGGGTTTATAAACCTTA TTAAGAGCAAGGATAATGTTGGTGTCAGGAATGCCGCTTTAGTCATAAAAGGCGGCGATACAAAAGTGGCAGAAAAAAAT AACGATGTTGGAGCAGAAAGTAAGCAACCTTTACTCGATATCGCGCTAAAGGGACTTAAAAGAACATTACCGCAACTGGA ACAAATGGATGGAAATAGCCTGCGAGAAAACTTCCAGGAGATGGCTTCAGGTAACGGCCCGCTGCGTTCATTAATGACGA ATTTACAGAATTTAAATAAAATTCCAGAGGCTAAACAACTTAATGATTATGTTACAACGTTAACAAATATTCAGGTCGGT GTAGCCCGGTTCTCACAATGGGGAACCTGTGGAGGAGAGGTTGAGAGGTGGGTTGATAAAGCCTCTACTCATGAATTAAC CCAGGCTGTAAAAAAAATTCACGTTATTGCTAAAGAACTGAAAAATGTTACAGCTGAACTTGAGAAAATAGAAGCCGGCG CGCCAATGCCACAGACGATGAGCGGACCGACACTGGGCCTGGCACGATTTGCGGTCAGCAGCATTCCAATTAATCAGCAA ACCCAGGTGAAACTGAGCGATGGAATGCCTGTGCCAGTGAATACGTTAACTTTTGACGGTAAGCCTGTGGCATTAGCCGG TTCGTACCCAAAAAATACGCCGGATGCGCTGGAAGCGCATATGAAAATGCTTCTTGAAAAAGAATGCTCGTGCCTGGTGG TGTTAACGTCGGAAGATCAGATGCAGGCAAAACAATTACCACCCTATTTCAGAGGGAGCTACACCTTTGGCGAGGTGCAT ACCAACAGCCAAAAAGTGAGCTCAGCCAGTCAGGGAGAAGCGATAGACCAATACAATATGCAACTGTCCTGCGGGGAAAA GCGGTATACAATCCCGGTATTGCATGTGAAAAATTGGCCAGATCACCAGCCGTTACCGTCTACGGATCAGTTAGAATACC TGGCGGATAGGGTGAAAAATAGTAACCAAAATGGCGCGCCGGGGCGTAGTTCATCAGATAAGCATTTACCGATGATTCAT TGTCTGGGCGGAGTGGGAAGAACCGGAACGATGGCGGCGGCCCTTGTACTTAAGGATAATCCTCATAGTAATCTGGAGCA GGTACGTGCAGATTTCCGGGATTCACGGAACAATAGAATGCTGGAAGACGCCTCACAGTTTGTACAACTAAAAGCAATGC AAGCCCAGTTGCTTATGACGACGGCAAGCTGA Protein sequence : MLKYEERKLNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQDQKIL QTFLHALTEKYGETAVNDALLMSRINMNKPLTQRLAVQITECVKAADEGFINLIKSKDNVGVRNAALVIKGGDTKVAEKN NDVGAESKQPLLDIALKGLKRTLPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLTNIQVG VARFSQWGTCGGEVERWVDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLARFAVSSIPINQQ TQVKLSDGMPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVH TNSQKVSSASQGEAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIH CLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| sptP | NP_461799.1 | protein tyrosine phosphatase/GTPase activating protein | Virulence | SPI-1 | Protein | 0.0 | 100 |
| sptP | YP_217797.1 | protein tyrosine phosphate | Not tested | SPI-1 | Protein | 0.0 | 99 |
| stpA | NP_457272.1 | tyrosine phosphatase (associated with virulence) | Virulence | SPI-1 | Protein | 0.0 | 95 |
| stpA | NP_806481.1 | tyrosine phosphatase | Virulence | SPI-1 | Protein | 0.0 | 95 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| sptP | NP_461799.1 | protein tyrosine phosphatase/GTPase activating protein | VFG0540 | Protein | 0.0 | 100 |
