Gene Information

Name : smpB (STM2688)
Accession : NP_461618.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2826484 - 2826966 bp
Length : 483 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACGAAGAAAAAAGCACATAAACCGGGCTCAGCCACCATCGCGCTGAATAAGCGCGCCCGGCACGAATACTTTATCGA
AGAAGAGTTCGAGGCTGGTCTCGCCCTGCAAGGCTGGGAAGTAAAATCTCTGCGCGCAGGAAAAGCCAATATCGGCGACA
GTTACGTTATCCTCAAAGATGGCGAGGCCTGGCTGTTTGGCGCAAACTTTACGCCGATGGCGGTCGCCTCGACACATGTT
GTATGCGACCCAACCCGAACCCGCAAACTGTTGTTAAATCAGCGTGAGCTTGATTCGCTGTATGGCCGTATTAATCGTGA
AGGTTATACTGTCGTCGCGCTTTCTCTGTACTGGAAAAATGCCTGGTGCAAAGTGAAGATCGGCGTGGCGAAAGGTAAAA
AACAACATGATAAACGTTCCGATCTTAAAGAACGTGAGTGGCAACTGGATAAAGCACGCATTATGAAAAATGCAGGCCGA
TAA

Protein sequence :
MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHV
VCDPTRTRKLLLNQRELDSLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKNAGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-51 71
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 8e-25 47
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 4e-21 43