Gene Information

Name : wzc (STM2116)
Accession : NP_461061.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : tyrosine kinase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3206
EC number : 2.7.10.2
Position : 2198900 - 2201059 bp
Length : 2160 bp
Strand : -
Note : Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide)

DNA sequence :
ATGACAGAAAAAGCAAAACAATCTGCGGCGGTTACGGGTAGCGATGAAATCGATATCGGGCGCCTGGTCGGAACGGTGAT
TGAAGCGCGTTGGTGGGTGTTGGGGACGACGGCCATATTTGCGCTGTGCGCGGTAATTTATACGTTCTTCGCCACGCCCA
TCTATAGCGCCGATGCGCTGGTACAGATTGAACAAAACGCCGGTAATTCGCTGGTACAGGATATCAATAGCGCATTAGCG
AATAAGCCGCCGGCTTCCGATGCGGAAATTCAGCTCATTCGATCGCGCCTGGTGCTGGGGAAGACCGTTGACGATCTGGA
TCTGGATATTGCCGTCACCAAAAACACCTTTCCGCTGTTCGGCGCCGGGTGGGAACGGCTGATGGGACGTCACAATGAAA
TGGTGAAAGTCACGACATTCACCCGACCAGAGACGATGAGCGGACAGATCTTCACCCTCAAAGTGCTGGGCGACAAACGT
TATCAGTTGGTTAGCGACGGCGGATTTAGCGCGCAGGGCGTTGTGGGCCAGCCACTCAATAAAGACGGCGTGACGATGCG
GGTAGAGGCGATTGACGCCCGTCCTGATACAGAATTTACGGTGAGTAAATTCTCAACGCTTGGCATGATTAATAACCTGC
AAAATAACCTCACCGTAACGGAAACCGGCAAAGATACCGGCGTTCTGAGCCTGACGTTCACGGGAGAGGATCGCGACCAG
ATCCGCGAAATTCTCAACAGTATTACCCGTAACTATCTGCAACAGGATATTGCGCGGAAATCTGAAGAGGCGGGGAAGAG
CCTGGCGTTTCTGGCAAAACAACTGCCGGAAGTCCGCAGCCGTCTGGATGTGGCGGAAAACAAGCTAAACGCTTTCCGCC
AGGATAAAGACTCGGTGGATTTACCGCTGGAGGCGAAGGCGGTGCTCGATTCGATGGTTAATATCGACGCCCAGTTGAAT
GAGTTGACGTTTAAAGAGGCGGAAATTTCCAAGCTCTTTACCAAAGCGCATCCGGCTTACCGCACCCTGCTGGAAAAACG
TAAAGCGCTGGAAGATGAAAAAGCCAAACTGAACGGGCGGGTGACGGCAATGCCGAAAACCCAGCAGGAGATTGTGCGTT
TGACCCGCGATGTGGAGTCCGGCCAGCAGGTCTATATGCAACTGCTTAATAAACAGCAGGAGCTGAAAATCACCGAAGCC
AGCACCGTTGGCGACGTGCGCATCGTTGACCCGGCGATTACCCAGCCGGGCGTGCTGAAGCCGAAAAAGGCGTTGATTAT
TCTCGGCAGCATTATTCTGGGATTAATGTTATCGATTGTCGGCGTGCTGCTGCGCTCGCTGTTTAATCGCGGTATCGAAA
GCCCGCAGGCGCTGGAGGAGCACGGGATCAGCGTCTATGCCAGTATTCCGCTGTCGGAATGGCAAAAAGCGCGCGATAGC
GTCAAAACCATTAAAGGAATTAAGCGTTACAAGCAGAGCCAACTGCTGGCGGTGGGCAATCCGACCGATCTGGCGATTGA
GGCGATTCGCAGCCTGCGCACCAGCCTGCATTTCGCCATGATGCAGGCGCAAAATAATGTACTCATGCTCACAGGCGTCA
GTCCCTCTATCGGCAAAACCTTTGTTTGCGCCAACCTGGCGGCCGTCATCAGCCAGACGCATAAACGGGTATTACTGATC
GACTGCGATATGCGTAAGGGCTACACCCATGAACTGCTCGGCACCAATAACGTGGACGGCTTATCTGACATTCTGGCGGG
CAAAGGCGAGATAGCCTCCTGCGCGAAACCCACGGCGATCGCTAATTTTGATCTTATTCCGCGCGGTCAGGTGCCGCCTA
ATCCATCGGAACTGCTGATGAGCGAGCGCTTCGGCGAGCTGATCGCCTGGGCAAGCAGCCGCTACGATCTGGTATTAATC
GACACGCCGCCGATTCTGGCCGTGACGGACGCCGCGATTGTGGGTCGCCACGCCGGGACGACGCTGATGGTGGCGCGTTA
TGCCGTCAACACCTTAAAAGAGGTGGAAACCAGTCTGAGCCGTTTTGACCAGAATGGCATTCAGGTCAAAGGCGTCATTC
TCAACTCCATTTTCCGCCGGGCGACGGGCTACCAGGATTATGGCTATTACGAGTATGAATACCAGTCAGATTCCAAATAA

Protein sequence :
MTEKAKQSAAVTGSDEIDIGRLVGTVIEARWWVLGTTAIFALCAVIYTFFATPIYSADALVQIEQNAGNSLVQDINSALA
NKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVTKNTFPLFGAGWERLMGRHNEMVKVTTFTRPETMSGQIFTLKVLGDKR
YQLVSDGGFSAQGVVGQPLNKDGVTMRVEAIDARPDTEFTVSKFSTLGMINNLQNNLTVTETGKDTGVLSLTFTGEDRDQ
IREILNSITRNYLQQDIARKSEEAGKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLN
ELTFKEAEISKLFTKAHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEA
STVGDVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQALEEHGISVYASIPLSEWQKARDS
VKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMLTGVSPSIGKTFVCANLAAVISQTHKRVLLI
DCDMRKGYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERFGELIAWASSRYDLVLI
DTPPILAVTDAAIVGRHAGTTLMVARYAVNTLKEVETSLSRFDQNGIQVKGVILNSIFRRATGYQDYGYYEYEYQSDSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf41 AAO18066.1 Orf41 Not tested TTSS locus Protein 1e-159 48