Gene Information

Name : umuC (STM1997)
Accession : NP_460948.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : 2.7.7.7
Position : 2079892 - 2081160 bp
Length : 1269 bp
Strand : -
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTCGCGCTCTGCGATGTTAATAGCTTTTACGCCTCCTGCGAAACGGTCTTTCGTCCTGATTTATGTGGCCGACCGGT
GGTGGTGTTATCAAACAATGATGGCTGCGTTATCGCGTGTAGCGCCGAGGCGAAACAGCTCGGTATCGCACCAGGTGAGC
CATACTTCAAACAGAAAGAACGCTTCCGGCGATCCGGTGTTGTTTGCTTCAGCAGTAATTACGAGCTTTACGCTGATATG
TCGAACCGGGTAATGACCACACTCGAGGAGATGGTGCCGCGGGTAGAAATTTACAGCATTGATGAGGCCTTTTGTGATCT
GACGGGGGTACGAAACTGCCGGGATCTGACAGATTTCGGGCGCGAGATAAGAGCGACGGTCCTGAAGCGCACGCACCTGA
CTGTCGGTGTAGGCATTGCCCAGACGAAAACCCTTGCCAAGCTGGCTAACCATGCTGCGAAAAAGTGGCAGCGCCAGACC
GACGGGGTGGTTGACTTGTCGAACATCGATCGCCAGCGTCGGCTGCTGGCCCTGATACCCGTGGAGGATGTCTGGGGTGT
CGGCAGGCGCATCAGTAAGAAGCTCAATGCCCTGGGCATCAAGACTGCTCTCGATCTCTCTGAACAAAGTACCTGGATCA
TCAGGAAACACTTCAATGTCGTGCTGGAGCGTACCGTGAGAGAGCTTCGCGGAGAGCCATGTCTGGAGCTCGAAGAGTTT
GCGCCGGCAAAGCAGGAAATCGTTTGTAGTCGCTCTTTCGGCGAGCGGGTCACAGACTATGAGGAAATGCGCCAGGCTGT
TTACAGCTACGCTGCGCGCGCGGCAGAAAAACTCCGCGGCGAGCACCAGTACTGCCGTTTCATTTCAACATTCGTCAAAA
CATCACCCTTTGCCCTGAACGAGCCCTACTACGGTAACAGCGCCGCGGTGACGCTTCTCACCCCCACGCAGGATTCACGT
GACATTATCAATGCGGCTGTGAAATGCCTGGATAAAATATGGCGCGACGGCCATCGCTACCAGAAAGCGGGGGTGATGCT
GGGTGACTTCTTCAGTCAGGGCGTAGCGCAACTCAACCTTTTCGACGATAACGCGCCGCGCGCCGGTAGTGCGAAGTTGA
TGGAAGTACTGGACCATCTTAACGCAAAAGACGGGAAGGGGACGCTGTACTTCGCCGGGCAGGGGATGTCGCAACAGTGG
GCTATGAAGCGAGAAATGCTTTCGCCTCGGTACACCACAAGATACTCTGATCTACTGCGTGTTAAGTAA

Protein sequence :
MFALCDVNSFYASCETVFRPDLCGRPVVVLSNNDGCVIACSAEAKQLGIAPGEPYFKQKERFRRSGVVCFSSNYELYADM
SNRVMTTLEEMVPRVEIYSIDEAFCDLTGVRNCRDLTDFGREIRATVLKRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
DGVVDLSNIDRQRRLLALIPVEDVWGVGRRISKKLNALGIKTALDLSEQSTWIIRKHFNVVLERTVRELRGEPCLELEEF
APAKQEIVCSRSFGERVTDYEEMRQAVYSYAARAAEKLRGEHQYCRFISTFVKTSPFALNEPYYGNSAAVTLLTPTQDSR
DIINAAVKCLDKIWRDGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRAGSAKLMEVLDHLNAKDGKGTLYFAGQGMSQQW
AMKREMLSPRYTTRYSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 8e-123 63
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 8e-123 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 6e-91 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-78 50