Gene Information

Name : sopE2 (STM1855)
Accession : NP_460811.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Virulence
Product : type III-secreted effector protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1952012 - 1952734 bp
Length : 723 bp
Strand : -
Note : SopE2 (gi|9651642); invasion-associated protein; secreted by SPI-1; interacts with chaperone InvB; guanine nucleotide exchange factor for Cdc42; activates Cdc42 which results in actin cytoskeleton rearrangements and internalization

DNA sequence : 
GTGACTAACATAACACTATCCACCCAGCACTACAGAATCCATAGAAGTGACGTTGAACCAGTAAAAGAAAAAACAACGGA
GAAGGACATTTTTGCAAAAAGTATTACTGCCGTTAGAAATAGCTTTATCAGCCTGTCGACGAGTCTGTCAGATCGTTTTA
GCCTGCATCAACAAACAGACATACCGACTACCCATTTTCATCGTGGGAACGCTTCTGAGGGTAGGGCGGTATTAACCAGT
AAAACTGTTAAAGATTTTATGCTGCAAAAGCTCAATAGTCTGGATATCAAAGGTAATGCGAGTAAAGATCCGGCCTATGC
TCGTCAGACATGCGAAGCCATATTATCAGCCGTGTACAGTAATAATAAAGATCAATGTTGTAAATTACTCATCAGTAAAG
GGGTCAGTATTACCCCCTTTTTGAAAGAGATAGGAGAGGCTGCGCAGAATGCGGGGCTACCTGGGGAGATAAAAAATGGC
GTATTTACTCCAGGTGGGGCAGGGGCGAATCCTTTTGTCGTCCCCCTCATTGCTTCCGCGAGTATTAAATATCCGCATAT
GTTTATAAATCATAATCAGCAGGTATCTTTTAAAGCGTATGCTGAGAAAATCGTTATGAAAGAGGTTACGCCGCTGTTTA
ATAAGGGGACGATGCCAACGCCACAACAATTTCAGTTAACTATAGAAAATATTGCGAATAAGTATCTTCAGAATGCCTCC
TGA

Protein sequence : 
MTNITLSTQHYRIHRSDVEPVKEKTTEKDIFAKSITAVRNSFISLSTSLSDRFSLHQQTDIPTTHFHRGNASEGRAVLTS
KTVKDFMLQKLNSLDIKGNASKDPAYARQTCEAILSAVYSNNKDQCCKLLISKGVSITPFLKEIGEAAQNAGLPGEIKNG
VFTPGGAGANPFVVPLIASASIKYPHMFINHNQQVSFKAYAEKIVMKEVTPLFNKGTMPTPQQFQLTIENIANKYLQNAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sopE NP_458691.1 invasion-associated secreted protein. Virulence SPI-7 Protein 4e-82 70
sopE NP_807899.1 invasion-associated secreted protein Virulence SPI-7 Protein 4e-82 70

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sopE2 NP_460811.1 type III-secreted effector protein VFG0467 Protein 1e-111 100