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Name : topB (STM1298) Accession : NP_460264.1 Strain : Salmonella enterica LT2 Genome accession: NC_003197 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 1376657 - 1378606 bp Length : 1950 bp Strand : + Note : decatenates replicating daughter chromosomes DNA sequence : ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGGGCGCGCCATTGCGGATGTGCTGCCAAAACCGCACCGTAAAGGCGA TGGTTTTATTGAGTGCGGAAACGGGCAGGTCGTCACCTGGTGTATTGGTCATTTGCTGGAACAGGCGCAGCCGGATGCGT ATGACAGCCGTTATGCGCGCTGGAATCTGGCTGACCTGCCTATCGTGCCGGAAAAATGGCAGCTTCAGCCTCGTCCTTCC GTCACCAAACAGCTCAATGTGATTAAGCGCTTTTTGCATCAAGCCGGTGAAATTATTCACGCCGGCGACCCGGATCGCGA AGGGCAGCTTCTGGTTGATGAAGTGCTGGATTATCTCCAGCTTCCTGCCGAAAAGCGCCAGCAGGTGCGGCGTTGTCTGA TAAACGACCTTAACCCGCAGGCGGTCGAGCGTGCTATTGACAGGCTGCGGGCGAACAGCGACTTCGTGCCGCTGTGCGTA TCCGCGCTGGCGCGAGCGCGAGCGGACTGGCTGTATGGCATTAATATGACCCGCGCTTACACGATCCTGGGCCGGAATGC CGGCTATCAGGGCGTGTTATCCGTGGGACGCGTGCAGACGCCGGTACTGGGGCTGGTGGTGCGGCGAGACGAAGAGATTG AGAACTTCGTCGCCAAAGACTTCTTTGAAGTGAAGGCGCACATCGTTACGCCTGCCGACGAGCGTTTTACCGCTATCTGG CAGCCGAGCGAGGCGTGCGAACCTTATCAGGATGAAGAGGGGCGCTTGCTTCATCGTCCGCTGGCGGAGCATGTAGTGAA CCGAATCAACGGTCAGCCCGCGCTGGTAACCAGTTATAATGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGC TCTCGACGCTACAGATTGAAGCCGCCAAACGCTTTGGCCTGAGCGCGCAAAACGTGCTTGATATTTGTCAGAAGCTATAT GAAACCCACAAACTGATTACCTATCCGCGTTCCGACTGCCGTTATCTGCCGGAAGAACACTTTGCCGGACGGCAGGCGGT CATGAACGCGATTAGCGTCCACGCCCCGGATTTACTGCCGCAGCCTGTGGTTAATCCTGATACGCGCAATCGCTGCTGGG ATGACAAAAAAGTGGATGCGCACCACGCGATTATCCCGACGGCGCGCAGTTCTTCTGTCCATTTGACGGAAAACGAAGCG AAAGTGTACACCCTGATTGCGCGTCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTTCGTAAATGCGTTATTGAACT GGAAATCGCCAAAGGGAAATTTGTCGCCAAAGCGCGTTTTCTGGCGGAAGCCGGTTGGCGGACGTTACTGGGCAGTAAAG AGCGCGACGAGGAAAACGACGGTACGCCGCTGCCGGTTGTCGCCAAAGGTGATGAGTTGCTGTGTGAAAAGGGGGAAGTG GTCGAACGCCAAACCCAGCCGCCGCGTCATTTCACTGATGCGACATTGCTTTCCGCGATGACCGGAATTGCCCGCTTCGT GCAGGATAAAGATCTGAAAAAGATCCTGCGCGCGACCGATGGGCTGGGGACGGAAGCCACGCGCGCCGGGATTATCGAGC TGCTGTTCAAACGTAGCTTTCTGACCAAAAAAGGTCGCTACATTCATTCTACCGATGCTGGCAAAGCGTTAATACATTCG CTGCCGGAGATGGCGGCCCGTCCAGATATGACCGCGCACTGGGAATCTGTTTTGACGCAAATCAGCGAAAAGCAGTGCCG TTACCAGGATTTCATGCAACCGCTGGTCGGCACGTTATATCAGCTGATCGAGCAGGCTAAGCGCACGCCGGTGAAGCGCT TCAGAGGGATAGTCGCGCCAGGCGGTGGAGACAAGAAAAAGAGCGCGCCGCGTAAGCGAGCGGGCAAAAAAAGCCCGCCT GCTGCGGAGACAGGCCGTCAGACCGAATAA Protein sequence : MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS VTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW QPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLY ETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEA KVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHS LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPP AAETGRQTE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 3e-103 | 41 |
| topB1 | YP_005176228.1 | DNA topoisomerase III | Not tested | ICEPmu1 | Protein | 1e-110 | 41 |
