Gene Information

Name : hpaE (STM1102)
Accession : NP_460075.1
Strain : Salmonella enterica LT2
Genome accession: NC_003197
Putative virulence/resistance : Unknown
Product : 4-hydroxyphenylacetate catabolism
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.60
Position : 1189507 - 1190973 bp
Length : 1467 bp
Strand : +
Note : similar to Escherichia coli aldehyde dehydrogenase; prefers NADP over NAD (AAC74382.1)

DNA sequence :
ATGAAGAAAATAAATCATTGGATTAACGGCAAAAATGTTGCAGGTAACGACTACTTCCAGACCACTAACCCGGCGACCGG
TGACGTGCTGGCGGAAGTGGCCTCCGGCGGTGAAGCAGAGGTGAACCAAGCTGTCGCGGCGGCAAAAGAGGCGTTCCCGA
AATGGGCCAACCTGCCGATGAAAGAGCGCGCGCGCCTGATGCGCCGCCTTGGCGACCTGATTGACCAGCATGTGCCGGAA
ATCGCGGCGATGGAAACCGCCGACACCGGCCTGCCTATTCACCAGACTAAAAACGTGCTGATCCCGCGCGCCTCGCATAA
CTTCGAATTCTTCGCCGAAGTGTGCCAGCAGATGAACGGCAAGACCTATCCTGTTGACGATAAAATGCTCAATTATACGC
TGGTGCAGCCCGTCGGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGCCGTTTATGACCGCGACCTGGAAAGTCGCGCCG
TGCCTGGCGCTGGGCAACACCGCGGTGCTCAAAATGTCCGAGCTGTCGCCGCTGACTGCCGACAGGCTGGGCGAGCTGGC
GCTGGAGGCAGGAATTCCGGCAGGCGTGCTGAACGTGGTGCAGGGCTATGGCGCGACGGCGGGCGATGCGCTGGTACGCC
ACCATGACGTGCGTGCGGTGTCGTTTACCGGCGGTACCGCCACCGGTCGCAATATCATGAAAAATGCCGGGCTGAAAAAA
TACTCGATGGAGCTGGGCGGCAAATCGCCGGTGCTGATTTTTGAAGATGCCGACATTGAGCGCGCGCTGGACGCCGCGCT
GTTCACCATCTTCTCGATCAACGGCGAACGCTGCACCGCCGGGTCGCGCATCTTTATCCAGCAGAGCATTTACCCTGAGT
TCGTGAAGCGCTTTGCCGAACGCGCGAATCGCCTGCGTGTCGGCGATCCGACCGACCCGAACACCCAGGTCGGCGCGCTG
ATTAGCCAACAGCACTGGGAAAAAGTCTCCGGTTATATTCGCCTCGGCATTGAAGAGGGCGCAACGCTGCTGGCGGGCGG
TGCGGAAAAACCCACTGACCTGCCTGCGCATCTGAAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGGCCGATGTCGACA
ACCGTATGCGCGTCGCGCAGGAAGAGATCTTTGGGCCAGTCGCCTGTCTGCTGCCATTCAAAGACGAAGCGGAAGGGTTA
CGTTTGGCGAACGACGTGGAATACGGTCTGGCCTCTTATATCTGGACCCAGGACGTGAGCAAAGTGTTGCGCCTGGCGCG
TGGGATTGAAGCCGGCATGGTCTTCGTCAACACCCAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCGGCGTGAAAGCCT
CCGGTACCGGGCGCGAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGGAAATGAAAAACGTCTGCATCTCAATGGGCGAC
CATCCTATCCCAAAATGGGGAGTTTGA

Protein sequence :
MKKINHWINGKNVAGNDYFQTTNPATGDVLAEVASGGEAEVNQAVAAAKEAFPKWANLPMKERARLMRRLGDLIDQHVPE
IAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK
YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPTDPNTQVGAL
ISQQHWEKVSGYIRLGIEEGATLLAGGAEKPTDLPAHLKGGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGL
RLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD
HPIPKWGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 0.0 92
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-76 43
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 4e-74 41