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Name : lysS (SAV_7296) Accession : NP_828472.1 Strain : Streptomyces avermitilis MA-4680 Genome accession: NC_003155 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 8700179 - 8703460 bp Length : 3282 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGAGTGCCACCGTGGAGGCCGCCGGACCCGGGCACGCCACCGGCCCGACACGGCCGTCCTGGGGCGGCTTCCTCAGCAA GGTGCCCGAGGGCTTCGCGACCTTCTTCGGCGCCCTCGGCCTCCTGTGCGTCCTGCTGGCCTTCATCGCGCCGCTGCGCC GTCTGCTGGGCCCGTTCGTGCGCGACCTCGACAGGTTCGTGGTCCCGGTCAGCGCCAACCTCGCCTACGGCGTCTTCCTC TTCCTGCTCGCCGCCGCGACCGCCGCCCGCAAGAAGGTCACCTGGTGGCTCGTGGTCGTCTACCTCGGCCTGGTGACCCT CGACGACCTGCTCGGCCTCGCCCTCGGCCACTACGCCGAGTCGGTCGTCTCGCTGATCGTGTGCTCACTCGCGCTGGCGC TGCTGATCGCGGCCCGCAAGGAGTTCTACGCGGCCTCCCGGCGCGGCGCCGCGTGGCGGGCCCTCGCCGTGCTGTTCGCC GGGCTCGGTGTGGCGATCCTGGTCGGGTGGGGCCTGGTCGAACTCTTCCCCGGCACGCTGCCGCGCGACCAGCGGCTGCT GTGGGCGGCCGACCGGGTCTGCGGCGGACTGGTGTCCGGACGCCGGTTCGACGGACGCACACCACGCCCCGTGTCCTTCC TCCTCGGCCTGTTCGGCGCACTCGCCCTGCTCAACGCCGCCGCCACCCTCTTCCGCTCCCAGCGCATGGAGTCGGCCCTG CACGGCGACGAGGAGCCGCGCATCCGCGCCCTGCTCGGGGCGTACGGCGCCGACGACTCCCTCGGCTACTTCGCCACCCG CCGGGACAAGGCCGTCGTCTTCTCGCCCAGCGGCAAGGCCGCCGTCACCTACCGGGTCGAGGCCGGTGTCTGCCTGGCCA GCGGGGACCCGGTCGGCGACCGCGAGGCCTGGCCGCACGCCATCGACGCCTGGCTCGACGTGGCCCGCCGCCACGCCTGG GCGCCCGCCGTCATGGGCGCCTCGGAAGAGGGCGCCAAGGCGTTCGCCCGCTCCGGACTCGGCGCGCTCCAACTGGGCGA CGAGGCGATCCTGAACACCGCCGACTTCGATCTCGACGGCCGCGACATGCGGGTGACCAGGCAGGCCGTCAACCGCGTGC GGCGCACCGGCGCCACCTGCCGGGTACGCCGGCACTCCACCCTCAGCGACGAGGAGATGGAGGAGGTCGTCGGCCGGGCC GACGCCTGGCGGGACACCGAGACCGAACGGGGCTTCTCGATGGCCCTGGACCGGCTCGGCGACCCCGCGGACGGCGACTG CCTCCTCGTCGAGGCCCTGGGAGAGGACGGAAAACTCCTCGCCCTGCTCTCCTTCGTGCCCTGGGGCGGGGACGGCGTCT CCCTCGACCTGATGCGCCGTGACCGTGCCGCGCCCAACGGAGTGATGGAGTTCATGGTCGCCGAGCTGTGTGCCGTGGCC GGACGGACGGGCATACGCCGGATCTCGCTGAACTTCGCGGTGTTCCGCTCGGTGTTCGAGGAGGGCGCCCGTATCGGTGC CGGGCCGGTCCTGCGTCTGTGGCGCCGACTGCTGCTCTTCTTCTCGAGATGGTGGCAGCTGGAGGCCCTGTACCGCTCCA ACGCCAAGTACCACCCGCAGTGGTACCCGCGCTTCATCTGCTACGGCGACACCGCCTCCCTCGCCCGGATCGGACTGGCG TCGGGCATCGCCGAGGGCTTCGTCTCCGTGCCCTCGCTGCGCAAGCTGTGGGGCAAGGGCCACTCCAAGGGGATCACCGA GCCGACGACGACCGAGGGTCTGCCGTCGCTGTCGGCGCTCGGCCTCGACAAGGGCGACGAGACCGGGCCGGGCGCGCCGG GACTGCCCGAACAGGTCCGGGTGCGCCTGAGCAAGCTCGACCGGCTGCGCGCGGACGGCACCGACCCCTACCCCGTGGGC ATCCCACCGCGCACCCACACCCTCGCCCGGGCCCGTGGCTCTCCGGCGGGCGAGCAGGTCACCGTCGCGGGCCGCGTCAT GCTCGTACGCGACTTCGGCGGCATCGTCTTCGCCGTGCTGCGCGACTGGTCGGGTGATCTGCAGCTCGCCCTCACCCGAT CCGGGTCCGGGCCCGCGCTCGACCGGTTCGGCAAGGACGCCGACATCGGCGACCACATCACCGCCACCGGCCGGACCGGC ACCAGCGACCGCGGCGAGCCGACGGTCTTCGTCACGGACTGGCAGCTCACCGGCAAATGCCTGCGCCCGCTGCCCGACAA GCACCGAGGCCTCGCCGACCCCGAGGCCAAGGTGCGCCGCCGCTATCTCGACCTGGTGGCGAGCCCCGACGCCCGCGCGG TCGTACGGGCCCGCTCCACCGCCGTCCAGGCGCTGCGCCAGGGGCTCCTCGACCGCGGCTATCTGGAGGTCGAGACGCCG ATGCTCCAGCAGATCCACGGCGGCGCGAACGCCCGGCCCTTCACCACCCACATCAACGCCTACGACCTCGACCTGTATCT GCGCATCGCCCCCGAGCTCTACCTGAAGCGGCTGTGCGTCGGCGGTCTGGAGAAGGTCTTCGAAATGGGGCGCACCTTCC GCAACGAAGGCGTCTCCTACAAGCACAACCCCGAGTTCACGATGCTGGAGGCCTATCAGGCGTTCGCCGACTACGACGTG ATGCTCGACCTCACCCGCGAACTGATCCAGGGCGCGGCCACCGCGGCCTTCGGGGGACCGGTCGCCCGCAAGAACGGCAC CGAGCACGACATCTCCGGACCGTGGCCGGTGAAGACGGTGTACGGCGCGATCTCCGAGGCACTGGGGGAGGAGCTGGACG CCGGGACGAGCCTTGAGGCCCTGCACCGGCACTGCGACCGGGCGGGCGTGCCGTACACCGCGGACGACGGCCGTGGTGAC GTGGTCCTGGAGATGTACGAGCGGCTGGTCGAGGAGAGGACCGGACTGCCCACCTTCTACAAGGACTTCCCGACCGACGT CTCCCCGCTCACCCGGCAGCACCGCGCCGATCCGCGCCTGGCCGAACGCTGGGACCTGGTCGCCTTCGGTACCGAACTGG GCACCGCCTACTCGGAGTTGACCGACCCGATGGAGCAGCGCAGACGGCTGACGGCGCAGTCCCTGCTGGCCGCCGGGGGA GACCCCGAGGCGATGGAGCTGGACGAGGACTTCCTCGACGCGCTGGAGTACGCGATGCCACCCACCGGCGGCCTCGGCAT CGGCGTGGACCGGCTCGTCATGTTCCTCACGGGCCTCACGATCCGGGAGACCCTGCCGTTCCCACTGGTACGCCGCCGCT GA Protein sequence : MSATVEAAGPGHATGPTRPSWGGFLSKVPEGFATFFGALGLLCVLLAFIAPLRRLLGPFVRDLDRFVVPVSANLAYGVFL FLLAAATAARKKVTWWLVVVYLGLVTLDDLLGLALGHYAESVVSLIVCSLALALLIAARKEFYAASRRGAAWRALAVLFA GLGVAILVGWGLVELFPGTLPRDQRLLWAADRVCGGLVSGRRFDGRTPRPVSFLLGLFGALALLNAAATLFRSQRMESAL HGDEEPRIRALLGAYGADDSLGYFATRRDKAVVFSPSGKAAVTYRVEAGVCLASGDPVGDREAWPHAIDAWLDVARRHAW APAVMGASEEGAKAFARSGLGALQLGDEAILNTADFDLDGRDMRVTRQAVNRVRRTGATCRVRRHSTLSDEEMEEVVGRA DAWRDTETERGFSMALDRLGDPADGDCLLVEALGEDGKLLALLSFVPWGGDGVSLDLMRRDRAAPNGVMEFMVAELCAVA GRTGIRRISLNFAVFRSVFEEGARIGAGPVLRLWRRLLLFFSRWWQLEALYRSNAKYHPQWYPRFICYGDTASLARIGLA SGIAEGFVSVPSLRKLWGKGHSKGITEPTTTEGLPSLSALGLDKGDETGPGAPGLPEQVRVRLSKLDRLRADGTDPYPVG IPPRTHTLARARGSPAGEQVTVAGRVMLVRDFGGIVFAVLRDWSGDLQLALTRSGSGPALDRFGKDADIGDHITATGRTG TSDRGEPTVFVTDWQLTGKCLRPLPDKHRGLADPEAKVRRRYLDLVASPDARAVVRARSTAVQALRQGLLDRGYLEVETP MLQQIHGGANARPFTTHINAYDLDLYLRIAPELYLKRLCVGGLEKVFEMGRTFRNEGVSYKHNPEFTMLEAYQAFADYDV MLDLTRELIQGAATAAFGGPVARKNGTEHDISGPWPVKTVYGAISEALGEELDAGTSLEALHRHCDRAGVPYTADDGRGD VVLEMYERLVEERTGLPTFYKDFPTDVSPLTRQHRADPRLAERWDLVAFGTELGTAYSELTDPMEQRRRLTAQSLLAAGG DPEAMELDEDFLDALEYAMPPTGGLGIGVDRLVMFLTGLTIRETLPFPLVRRR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 3e-166 | 46 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-166 | 46 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-166 | 46 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-166 | 46 |
