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Name : thcA (SAV_7177) Accession : NP_828353.1 Strain : Streptomyces avermitilis MA-4680 Genome accession: NC_003155 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 8543834 - 8545357 bp Length : 1524 bp Strand : - Note : PF00171: Aldehyde dehydrogenase family DNA sequence : ATGACCCGTTTCGCAGCGCCCGGCACCGACGGCGCGATCGTCTCCTACCAGGCGCGCTATGACCACTTCATCGGCGGCGA GTACGTGCCGCCGGCCCGCGGACAGTACTTCGAGAACCCGAGCCCGGTGAACGGGCAGCCGTTCACGGAGATCGCGCGGG GCACGGCCGAGGACGTGGAGCGCGCGCTCGACGCCGCGCACGCGGTCGCCCCCGCCTGGGGCCGCACGTCCGTGGCGGAG CGCTCCGACATCCTCCGCCGCATCGCCGACCGGATGGAGGCGAACCTGGAGAAGCTGGCGGTCGCGGAGAGCTGGGAGAA CGGCAAACCGGTCCGTGAGACGCTGGCCGCGGACATTCCGCTGGCCATCGACCACTTCCGCTACTTCGCGGGCGCGATCC GCGCGCAGGAGGGTTCCCTCGGCGAGGTCGACGACGACACGGTCGCGTACCACTTCCACGAGCCGCTCGGCGTGGTCGCG CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGACGTGGAAGCTCGCCCCGGCCCTCGCGGCGGGCAACGCGGTCGT CCTCAAGCCCGCCGAACAGACCCCGGCGTCCATCCACTACTGGCTGAGCCTGGTGGCCGACCTGCTGCCGCCGGGCGTGC TGAACATCGTCAACGGGTTCGGGGTGGAGGCGGGCAAACCGCTCGCGTCCAGCCCGCGGGTGGCGAAGGTGGCGTTCACC GGCGAGACCACGACGGGGCGGCTGATCATGCAGTACGCCTCCGAGAACATCACCCCGGTCACGCTCGAACTCGGCGGCAA GTCCCCGAACATCTTCTTCGACGACGTCTGGTCGGCGAACGACGACTTCCGTGACAAGGCGCTCGAAGGCTTCACGATGT TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCCCGGGCGCTCGTCCAGCGCGGCCAGTACGCCGAGTTCATGGAG GCGGCGGTCGCCCGCACCGAGCTGATCAAGACCGGTCACCCGCTCGACACGGACACGATGATCGGCGCCCAGGCGTCCAA CGACCAGCTGGAGAAGATCCTCTCCTATCTGGACATCGGCCGGCAGGAGGGCGCGAAGATCCTCACCGGCGGCGAACGCA TCGAGCACGACGGTGAGTTGAAGGGCGGTTACTACGTCCAGCCGACCATCTTCGAGGGCGACAACCGTATGCGGATCTTC CAGGAGGAGATCTTCGGTCCGGTCGTCTCGGTGACGTCGTTCAATGACTTCGACGACGCCATCAAGATCGCCAACGACAC GCTGTACGGGCTCGGCGCGGGCGTATGGACGCGGGACATCAACACCGCGTACCGCGCGGGCCGTGCCATCCAGGCGGGCC GCGTCTGGACGAACTGCTACCACGCCTACCCGGCCCACGCGGCGTTCGGCGGCTACAAGGGCTCGGGCATCGGCCGCGAG ACCCACAAGATGATGCTGGACCACTACCAGCAGACGAAGAACCTACTGGTGTCGTACTCGCCGAAGAAGCTGGGCTTCTT CTAG Protein sequence : MTRFAAPGTDGAIVSYQARYDHFIGGEYVPPARGQYFENPSPVNGQPFTEIARGTAEDVERALDAAHAVAPAWGRTSVAE RSDILRRIADRMEANLEKLAVAESWENGKPVRETLAADIPLAIDHFRYFAGAIRAQEGSLGEVDDDTVAYHFHEPLGVVA QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASIHYWLSLVADLLPPGVLNIVNGFGVEAGKPLASSPRVAKVAFT GETTTGRLIMQYASENITPVTLELGGKSPNIFFDDVWSANDDFRDKALEGFTMFALNQGEVCTCPSRALVQRGQYAEFME AAVARTELIKTGHPLDTDTMIGAQASNDQLEKILSYLDIGRQEGAKILTGGERIEHDGELKGGYYVQPTIFEGDNRMRIF QEEIFGPVVSVTSFNDFDDAIKIANDTLYGLGAGVWTRDINTAYRAGRAIQAGRVWTNCYHAYPAHAAFGGYKGSGIGRE THKMMLDHYQQTKNLLVSYSPKKLGFF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 7e-149 | 61 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 3e-154 | 59 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 3e-154 | 59 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 3e-154 | 59 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-153 | 59 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| thcA | NP_828353.1 | aldehyde dehydrogenase | VFG0082 | Protein | 3e-149 | 61 |
