Gene Information

Name : guaB3 (SAV_6884)
Accession : NP_828060.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : 1.1.1.205
Position : 8215841 - 8217292 bp
Length : 1452 bp
Strand : +
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
GTGCAGCACGTGCGTTTCCTCAACGACATCAAGCCCCCGTACGACCTGACGTACGACGACGTCTTCATGGTGCCGAGCCG
CTCCGCGGTCGGCTCCCGGCAGGGCGTGGACCTCACCTCCCCGGACGGCACGGGCACCACCATCCCGCTGGTCGTCGCCA
ACATGACCGCGATCGCCGGCCGCCGCATGGCCGAGACCGTGGCCCGCCGCGGCGGCCTCGTCGTCATTCCGCAGGACATC
CCGATCGAGGTCGTCACCGAGGTCGTCTCCTGGGTCAAGGGGCGTCATCTGGTCCTGGACACGCCGATCGTGCTCGTCCC
GCACCAGACCGTCGCGGACGCGCTGGCCCTGCTGCCGAAGCGGGCGCACAACGCGGGTGTCGTAGTGGACGAGGACGGCC
GCCCGGTCGGTGTGGTCACCGACACCGACCTGACCGGCGTCGACCGCTTCACTCAGCTGTCCGAGGTCATGTCGAGGGAT
CTGCTGCTGCTCGACGCGGACATCGAACCGCGCGAGGCCTTCAACAAGCTCGACGGCGCCAACCGCCGCTACGCGCCCGC
CGTCGACCGCGACGGCAGGCTGGCGGGCATCCTGACCCGCAAGGGCGCCCTGCGCGCCACGCTGTACACGCCCGCCACCG
ACGCCGACGGCAGGCTGCGCATCGCCGCCGCGGTCGGTATCAACGGCGATGTCGCGGGCAAGGCCAAGCAGCTGCTCGAC
GCGGGTGTCGACACGCTCGTCATCGACACGGCGCACGGCCACCAGGAGTCGATGATCAGCGCGATCAGGACCGTGCGCGC
GCTCGACCCCCAGGTGCCGATCGCCGCAGGCAACATCGTCGCCGCCGATGGTGTGAAGGACCTGGTCGAGGCGGGCGCGG
ACATCATCAAGGTCGGGGTCGGCCCCGGCGCCATGTGCACCACCCGCATGATGACGGGTGTGGGCCGGCCGCAGTTCTCG
GCCGTCATGGAGTGCGCCGCCGAGGCGAAGAAGTACGGCAAGCACGTGTGGGCCGACGGCGGTGTCCGTCACCCGCGCGA
CGTCGCGATGGCGCTCGCCGCCGGCGCGTCCAACGTGATGATCGGCTCCTGGTTCGCAGGCACGTACGAGTCGCCGGGCG
ACCTTCAGCAGGATGCCGACGGGCGCCTGTACAAGGAGTCGTTCGGCATGGCGTCGGCGCGTGCGGTGCGCAATCGCACG
TCGGAGGAGTCGGCGTACGACCGCGCCCGCAAGGGCCTGTTCGAGGAGGGCATCTCCACCTCGCGCATGTTCCTCGACCC
GGGCCGCCCGGGCGTCGAGGACCTGATCGACTCGATCATCGCGGGCGTCCGCTCCTCGTGCACCTACGCCGGCGCCAACT
CCCTGGAGGAGTTCACCGAGAAGGCCGTGGTCGGCATCCAGAGCGCGGCCGGCTACGCCGAGGGCAAGCCGCTGCACGCC
AGCTGGAGCTGA

Protein sequence :
MQHVRFLNDIKPPYDLTYDDVFMVPSRSAVGSRQGVDLTSPDGTGTTIPLVVANMTAIAGRRMAETVARRGGLVVIPQDI
PIEVVTEVVSWVKGRHLVLDTPIVLVPHQTVADALALLPKRAHNAGVVVDEDGRPVGVVTDTDLTGVDRFTQLSEVMSRD
LLLLDADIEPREAFNKLDGANRRYAPAVDRDGRLAGILTRKGALRATLYTPATDADGRLRIAAAVGINGDVAGKAKQLLD
AGVDTLVIDTAHGHQESMISAIRTVRALDPQVPIAAGNIVAADGVKDLVEAGADIIKVGVGPGAMCTTRMMTGVGRPQFS
AVMECAAEAKKYGKHVWADGGVRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLQQDADGRLYKESFGMASARAVRNRT
SEESAYDRARKGLFEEGISTSRMFLDPGRPGVEDLIDSIIAGVRSSCTYAGANSLEEFTEKAVVGIQSAAGYAEGKPLHA
SWS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 1e-151 66
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 6e-152 66
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 2e-151 66
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 2e-151 66