Gene Information

Name : fepC (SAV_6493)
Accession : NP_827669.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 7777815 - 7778702 bp
Length : 888 bp
Strand : +
Note : iron-siderophore uptake system transmembrane component

DNA sequence : 
ATGAGCGGCCGAGCGAACAAGAACACCCGAAGGAGCACTGTGAACCGCCTGTCCGCCGACAACGTCACCCTCGCCTACGA
CCAGCGCGTCATCGCCGAGCAGCTGTCGGTGGAGATTCCCGACAACTCCTTCACGGTGATCGTCGGCCCCAACGCGTGCG
GCAAGTCCACGTTGCTGCGTGCCCTTTCGCGGATGCTCAAGCCGGCCGAGGGGCGCGTCCTGCTCGACGGACAGGTCATC
CAGTCGATGCCCGCGAAGAAGGTCGCGCGGACGCTCGGGCTGCTCCCGCAGTCGTCGATCGCGCCCGACGGCATCACCGT
CGGCGACCTCGTGGGGCGCGGCCGCTATCCGCACCAGGGACTTCTGCGGCAGTGGTCGTCCGAGGACGAGCGGGTCGTGC
GGGAGTCCATGGAGTCGACCGGGGTCGCCGAGCTGGCCGACCGCTATGTCGACGAGCTCTCCGGCGGCCAGCGCCAGCGC
GTGTGGATCGCCATGGCGCTCGCGCAGCAGACGCCGCTGCTGCTGCTCGACGAGCCGACGACCTACCTCGACATCCAGCA
CCAGATCGACGTGCTCGACCTGTGCGCCGAACTCCACGAGGAGCAGGGCCGCACGCTCGTCGCCGTACTGCACGACCTCA
ACCACGCGGCCCGGTACGCCACCCATCTGATCGCCCTGCGCGACGGCCGGGCCGTCGCCGAGGGGGCGCCGAACGACATC
GTCACGGCCGAGCTGGTCGAGGAGGTCTTCGGCCTGCGCTGCCAGGTCATCGACGACCCGGAGACGGGCACACCGCTGGT
GGTGCCGGCGGCCCGCAGGGCGCGGGTGGCAGCCGCGGCGGCCGGACCGGCCGCGGAGGCCGCAACGGTGGCTACGGGGG
GCTCCTGA

Protein sequence : 
MSGRANKNTRRSTVNRLSADNVTLAYDQRVIAEQLSVEIPDNSFTVIVGPNACGKSTLLRALSRMLKPAEGRVLLDGQVI
QSMPAKKVARTLGLLPQSSIAPDGITVGDLVGRGRYPHQGLLRQWSSEDERVVRESMESTGVAELADRYVDELSGGQRQR
VWIAMALAQQTPLLLLDEPTTYLDIQHQIDVLDLCAELHEEQGRTLVAVLHDLNHAARYATHLIALRDGRAVAEGAPNDI
VTAELVEEVFGLRCQVIDDPETGTPLVVPAARRARVAAAAAGPAAEAATVATGGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 8e-62 52
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-66 51
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 4e-66 51
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 4e-66 51
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-66 51
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 3e-59 49
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 3e-59 49
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 1e-49 45
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-50 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC NP_827669.1 iron-siderophore uptake system ATP-binding protein BAC0164 Protein 7e-50 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC NP_827669.1 iron-siderophore uptake system ATP-binding protein VFG0925 Protein 5e-77 61
fepC NP_827669.1 iron-siderophore uptake system ATP-binding protein VFG1042 Protein 6e-50 45