Gene Information

Name : tkt2 (SAV_6315)
Accession : NP_827491.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 7582403 - 7584490 bp
Length : 2088 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGAGCACCAAGCCGACCACCACAGACCTCGAGTGGACCGAGTTGGACCAGCGGGCCGTGGACACCGCCCGCGTCCTGGC
CGCCGATGCCGTACAGAAGGTCGGCAACGGCCATCCCGGTACGGCGATGAGCCTCGCGCCTGCCGCGTACACCCTCTTCC
AGAAGGTGATGCGGCACGACCCGGCGGATCCCGACTGGGTCGGGCGCGATCGTTTCGTCCTTTCCGCGGGCCACTCGTCC
CTGACCCTCTACACCGAGCTCTACCTGGCCGGGTTCGGCCTGGAGCTGGACGACCTCAAGTCCTTCAGGACCTGGGGCAG
CCGGACTCCCGGCCACCCCGAGTACGGGCACACGCCCGGCGTGGAGACGACGACCGGCCCGCTGGGCCAGGGTGTCGCCA
ACGCGGTGGGCATGGCCATGGCCTCCCGCTACGAGCGCGGTCTGTTCGACCCGGACGCCGCACCCGGCACCTCCCCGTTC
GACCACTTCATCTACGCGATCGCCGGTGACGGCTGCCTCCAGGAGGGCATCTCCCACGAGGCGTCCTCGCTGGCCGGCCA
CCAGAAGCTCGGCAACCTGGTCCTGCTGTGGGACGACAACCACATCTCGATCGAGGGCGACACCGAGACGGCCGTCTCCG
AAGACACGGTGAAGCGCTACGAGGCGTACGGCTGGCATGTGCAGCGCGTGGCCCCGAAGCCGGACGGCGACCTCGACCCG
CACGCCCTCTACGACGCGATCCAGGCCGCCAAGGCGGTCACGGACAAGCCGTCGTTCATCGCGATGCGCTCGATCATCGC
CTGGCCCGCGCCGCACGCGCAGAACACCGAGGCCGCGCACGGCTCGGCGCTCGGCGAGGACGAGGTCGCGGCCACCAAGC
GCGTCCTCGGCTTCGACCCGGAGAAGAGCTTCGAGGTCGCCGAGGAGGTCCTCGCCCACACCCGTGAGGCCCTCGACCGC
GGCCGCGAGGCCAAGGCCGAGTGGGAGAAGGGCTTCGCCGCCTGGCGCACCGCCCAGCCGGAGCGCGCCGCCGAGTACGA
GCGCATCGCCGCGACCGAGCTGCCGGCCGGCTGGGAGGAGAAGCTCCCGGTCTTCGAGGTGGGCAAGGGCATCGCGACGC
GTGCCGCGTCCGGCAAGGTCCTCCAGGCACTCGGCGCGGTCATCCCCGAGCTGTGGGGCGGCTCCGCCGACCTGGCCGGC
TCGAACAACACCACGATCGACAAGAACTCCTCGTTCCTGCCGGCGGACAACCCGCTGCCGGAGGCCGACCCGTACGGCCG
CACGATCCACTTCGGCATCCGCGAGCACTCCATGGCCGCGGAGATGAACGGCATCGCGCTGCACGGCAACACCCGTATCT
ACGGCGGCACCTTCCTGGTGTTCTCCGACTACATGCGCAACGCCGTCCGCCTCTCCGCGCTGATGCACCTGCCGGTGACG
TACGTGTGGACCCACGACTCCATCGGTCTCGGCGAGGACGGCCCCACCCACCAGCCCGTCGAGCACCTCGCCTCGCTGCG
CGCCATCCCCGGCCTCAACGTCGTGCGTCCCGCGGACGCCAACGAGACGGCGATCGCCTGGCGCGAGATCCTCAAGCGCT
ACACCAAGGTGTTCGGCAAGGGCGCCCCGCACGGCCTCGCGCTGACCCGTCAGGGCGTACCGACGTACGAGCCCAACGAG
GACGCGGCCAAGGGCGGTTACGTGCTCTTCGAGGCCGAGGGCGGCGCTCCCGAGGTCATTCTCATCGGCACCGGCTCCGA
GGTGCACGTCGCCGTCGAGGCGCGCGAGCAGCTCCAGGCCGCGGGCGTGCCGACCCGGGTGGTGTCCATGCCGTCCGTGG
AGTGGTTCGAGGAGCAGGACCAGGGGTACCGGGACAGCGTCCTGCCGCCGTCGGTGAGGGCGCGGGTCGCGGTCGAGGCA
GGTATCGGTCTTACCTGGCACCGGTTCGTCGGAGACGCCGGACGCATTGTTTCGCTGGAGCACTTCGGTGCTTCGGCCGA
TGGCAAGGTGCTCTTCCGGGAGTTCGGTTTCACTCCCGAGAACGTCGCCGACGCCGCCCGGGAATCGATCGCCGCAGCCC
AGCGCTGA

Protein sequence :
MSTKPTTTDLEWTELDQRAVDTARVLAADAVQKVGNGHPGTAMSLAPAAYTLFQKVMRHDPADPDWVGRDRFVLSAGHSS
LTLYTELYLAGFGLELDDLKSFRTWGSRTPGHPEYGHTPGVETTTGPLGQGVANAVGMAMASRYERGLFDPDAAPGTSPF
DHFIYAIAGDGCLQEGISHEASSLAGHQKLGNLVLLWDDNHISIEGDTETAVSEDTVKRYEAYGWHVQRVAPKPDGDLDP
HALYDAIQAAKAVTDKPSFIAMRSIIAWPAPHAQNTEAAHGSALGEDEVAATKRVLGFDPEKSFEVAEEVLAHTREALDR
GREAKAEWEKGFAAWRTAQPERAAEYERIAATELPAGWEEKLPVFEVGKGIATRAASGKVLQALGAVIPELWGGSADLAG
SNNTTIDKNSSFLPADNPLPEADPYGRTIHFGIREHSMAAEMNGIALHGNTRIYGGTFLVFSDYMRNAVRLSALMHLPVT
YVWTHDSIGLGEDGPTHQPVEHLASLRAIPGLNVVRPADANETAIAWREILKRYTKVFGKGAPHGLALTRQGVPTYEPNE
DAAKGGYVLFEAEGGAPEVILIGTGSEVHVAVEAREQLQAAGVPTRVVSMPSVEWFEEQDQGYRDSVLPPSVRARVAVEA
GIGLTWHRFVGDAGRIVSLEHFGASADGKVLFREFGFTPENVADAARESIAAAQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-132 48
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-135 47