Gene Information

Name : pykA2 (SAV_6217)
Accession : NP_827393.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 7468937 - 7470373 bp
Length : 1437 bp
Strand : +
Note : -

DNA sequence :
ATGCGCCGAGCAAAGATCGTCTGTACTCTGGGCCCCGCCACCGACTCGTACGACCAGATCAAGGCACTGGTCGAGGCCGG
AATGGACGTAGCCCGCTTCAACCTCAGCCACGGCACCTACGCCGAGCACGAGGAGCGTTACCAGCACGTCCGCAAGGCCT
CCGACGAGACCGGGCGCAGCGTCGGAGTCCTCGGCGACCTTCAAGGTCCGAAGATCCGCCTCGGCCGCTTCAACGAAGGA
CCCGTACTCCTTGAACGCGGCGACACCTTCACCATCACCGTCGAGGAAGGCGTCGAAGGCGACCGCCAGACCTGCGGCAC
CACCTACGCCGGCCTCGCCGCCGACGTCACTCCCGGTGAGCGCATCCTCGTCGACGACGGCAAGGTCTGCCTCGAAGTCA
CCTCCGTCGACGGCCCCCGCGTCCACACCACCGTCGTCGAAGGCGGCATGGTCTCCGACCACAAGGGCCTGAACCTGCCC
GGCGTGGCCGTCTCGGTCCCCGCCCTCTCCGACAAGGACGAGGCCGACCTCCGCTGGGCCCTCCGTCAGGGCTTCGACGT
CATCGCGCTGTCCTTCGTACGCAGCGGCAAGGACATCAAGGACGTCCACCGGATCATGGACGAAGAAGGCCGCCGGCTCC
CCGTCATCGCCAAGGTGGAAAAGCCCCAGGCCGTCGAGAACATCGACGACATCGTCGCCGCCTTCGACGGAATCATGGTC
GCCCGCGGAGACCTCGGCGTGGAAATGCCGCTCGAACAGGTCCCGATCGTCCAGAAGCGCGCCATCAAACTCGCCAGGCG
CAACGCGAAGCCGGTCATCGTCGCGACGCAGATGCTGGACTCCATGATCGACAACTCCCGCCCGACCCGCGCGGAGGCCT
CGGACGTCGCCAACGCCGTCATCGACGGCACCGACGCGGTGATGCTGTCCGGCGAGACGAGCGTGGGCAAGTACCCCGTC
GAAACGGTCCGCACCATGTCCCGCATCGTGGAAGCGGCGGAAGAGGACATCCTGGCCACGGGCCTGCCGCCGCTGACCGA
ACGCAACAAGCCCCGCACCCAGGGCGGCGCGGTGGCCCGCGCGGCGGCCGAGATGGGCGACTTCCTCGGCGCCAAGTTCC
TGGTGGCGTTCACGCAGTCCGGAGACACGGTCCGCCGCCTCTCGCGCTACCGTTCCCCGATCCCGCTCCTGGCCTTCACC
CCGATGCCGGCGACGCGCTCCCAGCTCAACCTGACATGGGGCGTGGAGACGTTCCTGGGCCCGCACGTGGATTCGACGGA
CGCGATGGTGGACCAGGTCGACGAGCTGCTGCTCAAGTACGGCCGCTGCGAGAAGGGCGACGTGGTGGTCATCACGGCGG
GCTCACCCCCCGGCGTCTCGGGCTCGACGAACCTGGTCCGAGTCCACCACATCGGCGAGGACGACAGCCCCAAGTAG

Protein sequence :
MRRAKIVCTLGPATDSYDQIKALVEAGMDVARFNLSHGTYAEHEERYQHVRKASDETGRSVGVLGDLQGPKIRLGRFNEG
PVLLERGDTFTITVEEGVEGDRQTCGTTYAGLAADVTPGERILVDDGKVCLEVTSVDGPRVHTTVVEGGMVSDHKGLNLP
GVAVSVPALSDKDEADLRWALRQGFDVIALSFVRSGKDIKDVHRIMDEEGRRLPVIAKVEKPQAVENIDDIVAAFDGIMV
ARGDLGVEMPLEQVPIVQKRAIKLARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKYPV
ETVRTMSRIVEAAEEDILATGLPPLTERNKPRTQGGAVARAAAEMGDFLGAKFLVAFTQSGDTVRRLSRYRSPIPLLAFT
PMPATRSQLNLTWGVETFLGPHVDSTDAMVDQVDELLLKYGRCEKGDVVVITAGSPPGVSGSTNLVRVHHIGEDDSPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-82 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-82 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-82 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA2 NP_827393.1 pyruvate kinase VFG0479 Protein 2e-82 42