Gene Information

Name : trpE (SAV_6171)
Accession : NP_827347.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : anthranilate synthase component I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 7417784 - 7419265 bp
Length : 1482 bp
Strand : +
Note : with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine

DNA sequence :
ATGGACCTCGAGACGTTCCGCAAGCTGGCCACCGACCGCCGTGTCATTCCCGTCAGCCGCAAACTCCTCGCCGACGGCGA
CACCCCGGTCGGGCTCTACCGCAAGCTCGCCGCCGAGCGCCCCGGCACCTTCCTCCTGGAGTCCGCGGAGAACGGCCGCT
CGGCGTTCAAATGGTCCCGCTACTCCTTCGTGGGCGTCCGCTCCGCCGCCACCCTCACCGAGCGTGACGGGCAGGCGCAC
TGGCTCGGCACCCCGCCCGTGGGCGTCCCCACGGACGGCGACCCGCTCGCCGCCCTGCGCGCCACCATCGAGGCGCTGCA
CACGCCCCACGAGGAGGGCCTGCCGCCCTTCACCGGCGGCATGGTCGGCTATCTCGGCTACGACATCGTGCGCCGCCTGG
AGAAGATCGGCCCCGGCGAGCGCGACGATCTGAAACTTCCCGAGCTGACCATGCTCCTCACCAGCGATCTGGCCGTCATG
GACCACTGGGAGGGCTCCGTCCTGCTGATCGCCAACGCGATCAACCACAACGACCTCGACACGGGCGTCGACGAGGCCTA
CGCGGACGCGGTCGCCCGCCTCGACGCCATGGAGGCGGACCTGTCGCGCGCGGTCGCGCAGCCCCCCGCCGCCCTCCCGC
CCTCCGAACTCCCGGAGTACACCGCCCTCTGGGGCGGCCCCGACTTCCAGGACGCCGTCGAGGACATCAAGGAGCGCATC
CGGGCGGGCGAGGCGTTCCAGGTCGTCCCCTCCCAGCGCTTCGAAACGCCGTGCACGGCAAGCGCGTTGGACGTCTACCG
GGTACTGCGGGCGACCAACCCCTCACCGTACATGTACCTCTTCCGCTTCGAGGGCTTCGACGTGGTCGGCTCGTCCCCCG
AGGCCCTCGTCAAGGTCGAGGACGGGCAGGCGATGGTCCACCCCATCGCGGGCACCCGGCCGCGCGGCGCGACCCCGCAG
GAGGACCAGGCCCTCGCGGACGAGCTGCTGGCCGACCCCAAGGAGCGCGCCGAGCACCTGATGCTCGTCGACCTGGGGCG
CAACGATCTGGGGCGGGTCTGCGAGCCCGGTTCCGTCGAGGTCGTCGACTTCATGACCATCGAGCGCTACTCGCACGTGA
TGCACATCGTGTCGACCGTGACCGGGCGGGTCGCGCGGGGGCGTACGGCCTTCGACGTGCTGACGGCCTGCTTCCCGGCC
GGCACCCTCTCCGGCGCGCCCAAGCCCCGCGCCCTGCAGATCATCGACGAACTGGAGCCGTCCCGGCGGGGGCTGTACGG
CGGCTGCGTCGGCTACCTCGACTTCGCGGGCGACTCCGACACCGCCATCGCCATCCGCACGGCGCTGCTGCGCGACGGCA
CGGCGTACGTGCAGGCGGGCGCCGGCATCGTCGCGGACTCGGACCCGGTCGCCGAGGACGACGAGTGCCGCAACAAGGCG
GCGGCGGTCCTGCGCGCGGTCCACACGGCGAACCGGCTGTAG

Protein sequence :
MDLETFRKLATDRRVIPVSRKLLADGDTPVGLYRKLAAERPGTFLLESAENGRSAFKWSRYSFVGVRSAATLTERDGQAH
WLGTPPVGVPTDGDPLAALRATIEALHTPHEEGLPPFTGGMVGYLGYDIVRRLEKIGPGERDDLKLPELTMLLTSDLAVM
DHWEGSVLLIANAINHNDLDTGVDEAYADAVARLDAMEADLSRAVAQPPAALPPSELPEYTALWGGPDFQDAVEDIKERI
RAGEAFQVVPSQRFETPCTASALDVYRVLRATNPSPYMYLFRFEGFDVVGSSPEALVKVEDGQAMVHPIAGTRPRGATPQ
EDQALADELLADPKERAEHLMLVDLGRNDLGRVCEPGSVEVVDFMTIERYSHVMHIVSTVTGRVARGRTAFDVLTACFPA
GTLSGAPKPRALQIIDELEPSRRGLYGGCVGYLDFAGDSDTAIAIRTALLRDGTAYVQAGAGIVADSDPVAEDDECRNKA
AAVLRAVHTANRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00338 YP_008207803.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR25 Protein 2e-84 44
BJAB0868_00342 YP_008211668.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR26 Protein 2e-84 44