Gene Information

Name : rph (SAV_5170)
Accession : NP_826347.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 6277137 - 6277871 bp
Length : 735 bp
Strand : +
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
ATGTCTCGAATCGACGGCCGCACGCCCGAACAGCTCCGCCCCATCACCATCGAGCGCGGCTGGAGCAAGCACGCCGAGGG
CTCCGTCCTCGTCTCCTTCGGCGACACGAAGGTCTTCTGCACCGCCTCCGTCACCGAAGGCGTCCCGCGCTGGCGCAAGG
GCAGCGGCGAAGGCTGGGTCACCGCCGAGTACTCCATGCTCCCGCGCGCCACCAACACCCGCGGCGACCGCGAGTCGGTC
CGGGGCAAGATCGGCGGCCGTACGCACGAGATCAGCCGTCTGATCGGCCGCTCCCTGCGCGCGGTCATCGACTACAAGGC
GCTCGGCGAGAACACGATCGTCCTCGACTGCGACGTCCTCCAGGCCGACGGCGGCACCCGCACGGCCGCGATCACGGGCG
CGTACGTCGCCCTCGCCGACGCGGTCGCCTGGGCCCAGGGCCGCAAGCTCGTGAAGGCGGGCCGAAAGCCGCTCACCGGC
ACGGTCAGCGCGGTCTCGGTGGGCATCGTGGGCGGGGTGCCGTTGCTGGACCTCTGCTACGAGGAGGACGTGAAGGCCGA
CACCGACATGAACGTCGTCTGCACCGGCGACGGCCGCTTCGTCGAGGTCCAGGGCACCGCCGAGGCGGAACCCTTCGACC
GCAAGGAGCTCAACGCCCTTCTCGACCTGGCGGTTTCGGGCTGCGACGAACTGGCGGTGATCCAACGTGCGGCCCTGGAG
GCAACCACACGCTGA

Protein sequence :
MSRIDGRTPEQLRPITIERGWSKHAEGSVLVSFGDTKVFCTASVTEGVPRWRKGSGEGWVTAEYSMLPRATNTRGDRESV
RGKIGGRTHEISRLIGRSLRAVIDYKALGENTIVLDCDVLQADGGTRTAAITGAYVALADAVAWAQGRKLVKAGRKPLTG
TVSAVSVGIVGGVPLLDLCYEEDVKADTDMNVVCTGDGRFVEVQGTAEAEPFDRKELNALLDLAVSGCDELAVIQRAALE
ATTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 2e-54 63