Gene Information

Name : pncB (SAV_5158)
Accession : NP_826335.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : nicotinate phosphoribosyltransferase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1488
EC number : 2.4.2.11
Position : 6265776 - 6267104 bp
Length : 1329 bp
Strand : -
Note : catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate

DNA sequence :
GTGAACCCAGCGGACCTTGGGCTGCCGGTGGATGTTCCGTCGACGGCACTCTTCACCGACCAGTACGAACTGACGATGCT
CCAGGCCGCACTGGCCGCCGGGACCGCCGAACGGCGCTCGGTCTTCGAGGTCTTCACCCGACGGCTGCCCGAGGGGCGGC
GGTACGGCGTCGTGGCCGGGACCGGGCGCGTCCTGGACGCGGTCGAGAACTTCCGCTTCGACGCCGCCCTCCTCGGCTTC
CTGCGCGAGCGGCGGATCGTGGACGAGCCGACCCTGGAGTGGCTCGCCTCGTACCGCTTCCGGGGGGACATCTGGGGCTA
CCCCGAGGGCGAGGTCTACTTCCCGGGCTCGCCCCTGCTGCGGGTCGAGGGCTCGTTCGCGGAGTGCGTGCTCCTGGAGA
CCGTGATCCTGTCCATCCTCAACCACGACTCGGCCATCGCGGCCGCCGCCTCCCGCATGTCCTCCGCCGCCGGTGCGCGC
CCGCTGATCGAGATGGGCGCCCGGCGCACCCACGAGCTGGCCGCCGTCGCCGCCGCGCGGGCCGCGTACGTCGGCGGCTT
CGCGACCACGTCCGACCTGGCCGCGGGCTTCCGGTACGGGATTCCGACGGTCGGTACCAGCGCGCACGCGTTCACGTTGC
TGCACGACACCGAGCGGGACGCCTTCCGGGCCCAGGTGGACTCGCTGGGCCGGGGCACGACGCTGCTCGTGGACACGTAC
GACGTCGCCGAGGCCGTACGCATGGCCGTCGAGATCGCCGGGCCCGAGCTCGGTGCCGTGCGCATCGACTCCGGGGACCT
GCTGCTCGTCGCGCACCGGGTGCGGCAGCAGCTGGACGACCTGGGCGCGACCGAAACGAAGATCGTGGTGACCTCGGACC
TGGACGAGTACGCGATCGCCTCGCTGGCCGCGGCGCCCGTGGACGCGTACGGCGTCGGCACCCAGCTGGTGACGGGATCC
GGCCATCCGACATGTTCGATGGTCTACAAACTGGTGGCCCGCGCCCACTCGGCGGACCCGGCGGCTCCGCTGGAGCCGGT
GGCGAAGAAGTCGACCGGCGGGAAGACCTCCATCGGCGGGCGGAAGTGGGCAGCGCGCCGGCTCGACGAGCACGGGGTGG
CCGAGGCCGAGGTGATCGGGACGGGGCCCGTGCCGGCCGGTCTGGAGGGCCGTCAGCTGCTCGTGGAGCTGATAAAGGGC
GGCCAGGTCGTCGCCCGCGAGTCCCTCGACGTCGTACGGGACCGGCACGCGGCCGCCCGTGCCGGTCTGCCGTTGTCGGC
GAACCAGCTGTCGCGCGGGGAGCCGGTGATCCCGACGGAGTACGTGTGA

Protein sequence :
MNPADLGLPVDVPSTALFTDQYELTMLQAALAAGTAERRSVFEVFTRRLPEGRRYGVVAGTGRVLDAVENFRFDAALLGF
LRERRIVDEPTLEWLASYRFRGDIWGYPEGEVYFPGSPLLRVEGSFAECVLLETVILSILNHDSAIAAAASRMSSAAGAR
PLIEMGARRTHELAAVAAARAAYVGGFATTSDLAAGFRYGIPTVGTSAHAFTLLHDTERDAFRAQVDSLGRGTTLLVDTY
DVAEAVRMAVEIAGPELGAVRIDSGDLLLVAHRVRQQLDDLGATETKIVVTSDLDEYAIASLAAAPVDAYGVGTQLVTGS
GHPTCSMVYKLVARAHSADPAAPLEPVAKKSTGGKTSIGGRKWAARRLDEHGVAEAEVIGTGPVPAGLEGRQLLVELIKG
GQVVARESLDVVRDRHAAARAGLPLSANQLSRGEPVIPTEYV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1473 YP_001800867.1 nicotinate phosphoribosyltransferase Not tested Not named Protein 2e-80 64