Gene Information

Name : smpB (SAV_5107)
Accession : NP_826284.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 6202121 - 6202654 bp
Length : 534 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGTACGTACCGAAAGAGTCCCAGCCGAAGCAGGGCGGGGGAGCCTCCGGCAAGGTCAAGGACGGCAAGCGCAAGATCGT
CGCGCAGAACAAGAAGGCGCGCCACGACTACGCGATCATCGACACCTATGAGGCCGGGCTCGTGCTCACCGGCACGGAGG
TGAAGTCGCTGCGTCAGGGACGCGCCTCGCTGACCGACGGCTTCGTCCAGATCGACGGGAACGAGGCGTGGCTGCACAAC
GCCCACATCCCCGAATACAGCCAGGGCACGTGGACCAACCACACCGTGCGCCGCAAGCGGAAGCTGCTCCTGCACCGCGA
GGAGATCGACAAGCTGGCGTCGAAGTCCGAGGAGACGGGTCACACGATCGTGCCCCTCGCCCTGTACTTCAAGGACGGTC
GCGCGAAGGCCGAGATCGCGCTGGCACGGGGTAAGAAGGAGTACGACAAGCGGCAGACCCTGCGGGAGAAGCAGGACCGG
CGGGAGTCGGACCGGGCGATCGCGGCGGCCAAGCGCAAGCAGCGGGGCGAGTAG

Protein sequence :
MYVPKESQPKQGGGASGKVKDGKRKIVAQNKKARHDYAIIDTYEAGLVLTGTEVKSLRQGRASLTDGFVQIDGNEAWLHN
AHIPEYSQGTWTNHTVRRKRKLLLHREEIDKLASKSEETGHTIVPLALYFKDGRAKAEIALARGKKEYDKRQTLREKQDR
RESDRAIAAAKRKQRGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 4e-36 54
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-29 52