Gene Information

Name : clpC2 (SAV_4697)
Accession : NP_825874.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5721983 - 5724508 bp
Length : 2526 bp
Strand : +
Note : PF07724: ATPase family associated with various cellular activities (AAA)

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGGCACATCCCCTTC
ACTCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGTGAGGGCGAGGGTGTCGCCGCCCAGGTCCTGGTCAAGCTGGGCGCAGACCTCAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGACCGCCGCCGCCGGCGGTCCTGCCGAGGGCACC
CCCTCCACGTCCCTGGTCCTCGACCAGTTCGGCCGGAATCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACGAAGAACAACCCGGTCCTGATCGGTGAGC
CCGGTGTCGGCAAGACCGCCGTCGTCGAGGGCCTCGCTCAGGCGATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTGGGTGCGCTGGTCGCCGGTTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTGAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTCGTCGGTGCGGGTGCCG
CCGAGGGCGCCATCGACGCGGCTTCGATCCTGAAGCCGATGCTGGCCCGCGGTGAGCTGCAGACCATCGGCGCCACCACA
CTCGACGAATACCGCAAGCACCTCGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCGATCCAGGTGGCGGAGCCTTC
CCTCCCCCACACGATCGAGATCCTCAAGGGCCTGCGCGACCGTTACGAGGCACACCACCGCGTCTCCATCACGGACGAGG
CTCTCGTCCAGGCCGCGACGCTCGCGGACCGTTACATCTCGGACCGCTTCCTCCCGGACAAGGCGATCGACCTGATCGAC
GAGGCGGGTTCCCGGATGCGGATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCGGGCGT
GCGCCGCGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCGGCTTCTCTCCGCGACAAGGAGAAGCAGCTCC
TGGCCGCGAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAGCTGATC
GCCGAGGTCCTCGCGACCGCCACCGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGCCTGCTGCGCATGGA
GGACGAGCTCCACAAGCGGGTCATCGGCCAGAAGGACGCCGTCAAGGCGCTCTCGAAGGCGATCCGTCGTACGCGTGCGG
GTCTGAAGGACCCGAAGCGGCCGGGTGGTTCGTTCATCTTCGCGGGCCCGTCCGGTGTCGGTAAGACCGAGCTGTCCAAG
GCGCTCGCCGAGTTCCTGTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
CTCGCGTCTGTTCGGTTCGCCTCCCGGCTACGTGGGCTACGAAGAGGGCGGGCAGCTGACCGAGAAGGTCCGCCGCAAGC
CGTTCTCCGTCGTCCTGTTCGACGAGGTCGAGAAGGCCCACCCGGACATCTTCAACTCGCTGCTCCAGATCCTGGAGGAC
GGTCGTCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCCGCCCAGGGCGACACGAAGTCCAACTACGAGCGCATGAAGAACAAGG
TCGCGGACGAGCTCAAGCAGCACTTCCGCCCCGAGTTCCTCAACCGCGTCGACGACGTGGTCGTCTTCCCGCAGCTCACC
CAGGACGACATCCTCCGGATCGTCGACCTGATGATCACCAAGGTCGACGAGCGCCTCAAGGACCGGGACATGGGCATCGA
ACTCGCCCAGTCCGCGAAGGAACTGCTCGCGAAGAAGGGTTACGACCCCGTTCTGGGCGCGCGGCCGCTGCGCCGCACGA
TCCAGCGCGAGATCGAGGACACCCTCTCCGAGAAGATCCTCTTCGGGGAGCTGCGTCCGGGCCACATCGTGGTCGTCGAC
ACGGAGGGCGAGGGCGAGACCAAGACCTTCACCTTCCGTGGCGAGGAGAAGTCGGCCCTGCCCGACGTCCCCCCGATCGA
GCAGGCGGCCGGCGGCGCCGGTCCGAACCTGAGCAAGGACGCGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETAAAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
ALAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDTKSNYERMKNKVADELKQHFRPEFLNRVDDVVVFPQLT
QDDILRIVDLMITKVDERLKDRDMGIELAQSAKELLAKKGYDPVLGARPLRRTIQREIEDTLSEKILFGELRPGHIVVVD
TEGEGETKTFTFRGEEKSALPDVPPIEQAAGGAGPNLSKDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 77

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC2 NP_825874.1 ATP-dependent Clp protease VFG0079 Protein 0.0 61
clpC2 NP_825874.1 ATP-dependent Clp protease VFG0080 Protein 3e-151 54