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Name : nhaA (SAV_4598) Accession : NP_825775.1 Strain : Streptomyces avermitilis MA-4680 Genome accession: NC_003155 Putative virulence/resistance : Unknown Product : pH-dependent sodium/proton antiporter Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG3004 EC number : - Position : 5612114 - 5613514 bp Length : 1401 bp Strand : - Note : exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH DNA sequence : GTGGCCGCCCCCCGCACCAGCACCCGCAAGTTCCTCGGACGGCTCTCGCTGCCCGAGCGGAACTTCGTCGCGGAGGCGCT GCGCACCGAGACCGTCGGCGGCGTCCTGCTCCTCCTCGCCGCGATCACCGCGCTGATCTGGGCGAACGTACCCGCGCTGC ACCACAGCTACGAGAGCGTCAGCCACTTCCACTTCGGCCCCGCCCCCCTCGGCCTGGACCTCTCCGTCCAGCACTGGGCC GCCGACGGGCTGCTCGCGGTCTTCTTCTTCGTCGCCGGCATCGAACTCAAGCGCGAGCTGGTCGCAGGGGACCTCAAGGA CCCCAAGGCGGCCGCGCTCCCCGTGGCCGCCGCCCTGTGCGGCATGGCCGTACCCGCGCTCGTCTACACCCTCACCAACC TCACCGGTGGCGGCTCCCTCCGCGGCTGGGCGGTACCCACGGCCACCGACATCGCCTTCGCGCTGGCCGTCCTCGCGGTC ATCGGGACCTCGCTCCCGTCCGCGCTGCGCGCCTTCCTGCTCACCCTCGCCGTCGTCGACGACCTCTTCGCGATCCTGAT CATCGCGGTCTTCTTCACCGCCGACCTGAACTTCGCCGCCCTCGCCGGCGCCGTGATCGGCCTCGCCGTCTTCTGGCTGC TGCTGCGCAAGGGCGTACGCGGCTGGTACGTGTACGTGCCGCTCGCGCTCGTCATCTGGGGGCTGATGTACAACAGCGGC ATCCACGCCACCATCGCCGGTGTGGCGATGGGACTGATGCTGCGCTGCCACCGCCACCAGGGTGAGGAGCACGCTCCCGG TGAGCACATCGAGCATCTTGTACGCCCCCTGTCGGCCGGCCTGGCCGTGCCCCTGTTCGCCCTGTTCAGCGCGGGTGTCG TGATCTCCGGGGGTGCGCTCGGGGACGTGTTCACCAGGCCGGAGACCCTCGGGGTGGTCCTCGGGCTCGTCGTCGGCAAG GCGATCGGCATCTTCGGCGGAACGTGGCTGACGGCCCGCTTCACCCGCGCGTCGCTCAGCGACGACCTCGCCTGGCCCGA CGTCTTCGCGGTGGCGTCGCTGGCCGGCATCGGCTTCACCGTCTCCCTGCTCATCGGCGAACTCGCGTTCGACGGTGATC CGGTGCTGACCGACGAGGTCAAGGCCGCCGTCCTCACCGGTTCCCTTCTGGCGGCGCTGATCGCGACGACGCTGCTGAAG CTGCGCAACGCCAAGTACCGTGCCCTGTGCGAGGACGAGGAGCGCGACGAGGACAGCGACGGCATCCCCGACATCTACGA GCAGGACAACCCGGCGTACCACCTGCGCATGGCCGAGATCTACGAGCGCAAGGCCGCCGAGCACCGAAGGCTTGCCGAAG TGACGGGCGGGGCAGGCGCGGAGAACGATGGTCCGGCATGA Protein sequence : MAAPRTSTRKFLGRLSLPERNFVAEALRTETVGGVLLLLAAITALIWANVPALHHSYESVSHFHFGPAPLGLDLSVQHWA ADGLLAVFFFVAGIELKRELVAGDLKDPKAAALPVAAALCGMAVPALVYTLTNLTGGGSLRGWAVPTATDIAFALAVLAV IGTSLPSALRAFLLTLAVVDDLFAILIIAVFFTADLNFAALAGAVIGLAVFWLLLRKGVRGWYVYVPLALVIWGLMYNSG IHATIAGVAMGLMLRCHRHQGEEHAPGEHIEHLVRPLSAGLAVPLFALFSAGVVISGGALGDVFTRPETLGVVLGLVVGK AIGIFGGTWLTARFTRASLSDDLAWPDVFAVASLAGIGFTVSLLIGELAFDGDPVLTDEVKAAVLTGSLLAALIATTLLK LRNAKYRALCEDEERDEDSDGIPDIYEQDNPAYHLRMAEIYERKAAEHRRLAEVTGGAGAENDGPA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| nhaA1 | YP_001220808.1 | NahA family Na(+)/H(+) antiporter | Not tested | chp/tomA region | Protein | 7e-59 | 53 |
