Gene Information

Name : purA (SAV_4547)
Accession : NP_825724.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 5553370 - 5554653 bp
Length : 1284 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
GTGCCCGCACTTGTGCTGCTCGGTGCTCAGTGGGGTGACGAAGGCAAGGGAAAGGCCACCGACCTGCTCGGTGGTTCAGT
GGATTATGTGGTGCGCTACCAGGGCGGCAACAACGCCGGCCACACGGTAGTCGTGGGCGACCAGAAGTATGCCCTCCACC
TCCTCCCTTCCGGAATCCTCACACCGGAGTGCACTCCGGTCATCGGAAACGGTGTCGTCGTCGACCCGTCGGTCCTGTTC
TCCGAGCTGAACGGACTGAACGAGCGAGGCGTCGACACGTCCAAGCTCCTGATCAGCGGAAACGCGCACATCATCACGCC
TTACAACGTGACGGTGGACAAGGTGACGGAACGCTTCCTCGGGAAGCGGAAGATCGGCACGACCGGGCGCGGCATCGGCC
CGACCTACGCCGACAAGATCAACCGCGTGGGTATCCGCATCCAGGACCTGTACGACGAGTCGATCCTGACGCAGAAGGTC
GAGGCGGCCCTCGACGGCAAGAACCAGCTCCTCACCAAGGTCTTCAACCGGCGCGCCATCGAGGCCGGCCAGGTCGTCGA
GGAGCTGCTGACGTACGCGGACCGGCTCAAGCCGTACGTCGCGGACACGGTGCTCGTCCTCAACAAGGCGCTCGACGACG
ACAAGGTCGTGCTCTTCGAGGGCGGCCAGGGCACGCTCCTGGACATCGACCACGGTACGTATCCCTTCGTCACGTCCAGC
AACCCCACCGCGGGCGGGGCGTGCACGGGCTCCGGTGTGGGCCCGACGAAGATCAGCCGGGTCATCGGCATCCTGAAGGC
GTACACGACCCGTGTCGGCGCCGGTCCCTTCCCGACCGAGCTCCTCGACGAGGACGGCGAGGCGCTGCGCCGCATCGGCG
GCGAGCGGGGCGTCACGACCGGCCGGGACCGCCGCTGCGGCTGGTTCGACGCGGTCATCGCCCGCTACGCGACCCGGGTG
AACGGTCTGACGGACTTCTTCCTCACCAAGCTCGACGTCCTGACGGGCTGGGAGCAGATCCCGGTCTGCGTGGCGTACGA
GATCGACGGCAAGCGCGTCGAGGAGCTCCCGTACTCGCAGACCGACTTCCACCACGCGAAGCCGATCTACGAGAACCTCC
CGGGCTGGTCGGAGGACATCACGAAGGCCAAGACCTTCGAGGACCTCCCGAAGAACGCCCAGGCCTACGTCAGGGCCCTG
GAGGAGATGTCGGGCGCCCCGATCTCCGCGATCGGAGTGGGCCCGGGCCGCGACGAGACGATCGAGATCAACTCGTTCAT
CTAG

Protein sequence :
MPALVLLGAQWGDEGKGKATDLLGGSVDYVVRYQGGNNAGHTVVVGDQKYALHLLPSGILTPECTPVIGNGVVVDPSVLF
SELNGLNERGVDTSKLLISGNAHIITPYNVTVDKVTERFLGKRKIGTTGRGIGPTYADKINRVGIRIQDLYDESILTQKV
EAALDGKNQLLTKVFNRRAIEAGQVVEELLTYADRLKPYVADTVLVLNKALDDDKVVLFEGGQGTLLDIDHGTYPFVTSS
NPTAGGACTGSGVGPTKISRVIGILKAYTTRVGAGPFPTELLDEDGEALRRIGGERGVTTGRDRRCGWFDAVIARYATRV
NGLTDFFLTKLDVLTGWEQIPVCVAYEIDGKRVEELPYSQTDFHHAKPIYENLPGWSEDITKAKTFEDLPKNAQAYVRAL
EEMSGAPISAIGVGPGRDETIEINSFI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 9e-111 53