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Name : serS1 (SAV_4244) Accession : NP_825421.1 Strain : Streptomyces avermitilis MA-4680 Genome accession: NC_003155 Putative virulence/resistance : Unknown Product : seryl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0172 EC number : 6.1.1.11 Position : 5204797 - 5206074 bp Length : 1278 bp Strand : + Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGATTGACCTTCGCCTGCTCCGTGAGGACCCCGACCGTGTTCGCGCCTCCCAGCGCGCCCGTGGAGAGGACGTCGCGCT CGTCGACTCCCTCCTCTCCGCCGACGAGCGGCGCAGGTCGTCCGGCGTCCGCTTCGACGAGCTCCGTTCCGAGCAGAAGG CGCTCGGCAAGCTGATCCCCAAGGCCTCCCCCGAAGAGCGCGCCGAGCTGCTGAAGAAGGCCGAGCAGCTCAAGGCCGAC GTCAAGGCGGCCGACGTCGAGCAGCACGAGGCCGACGAGGAGGCCAAGCGCCTTCTCCTCCAGCTCGGCAACCTCGTGCA CCCCGACGTCCCGGTCGGCGGCGAGGAGGACTTCGTCGTCCTGGAGACGCACGGCACCATCCGTGACTTCGGCGCCGAGG GCTTCGAGCCCAAGGACCACCTGGAGCTCGGCGAGGCGCTCGGCGCCATCGACGTCGAGCGGGGCGCCAAGGTGTCCGGC TCGCGCTTCTACTACCTGACGGGCGTCGGCGCGCTCCTGGAGCTCGCCCTCGTCAACGCGGCGATCGCGCAGGCCACCGA GGCCGGCTTCATCCCGATGCTGACCCCCGCGCTGGTCCGCCCGCGCGCCATGGAGGGCACCGGCTTCCTCGGCCAGGCGT CGGAGAACGTGTACCACCTGGAGAAGGACGACTACTACCTGGTCGGCACCTCCGAGGTCCCGCTCGCGGCGTACCACATG GACGAGATCCTCGACGCCGACAAGCTGCCGATGCGGTACGCGGGCTTCTCGCCGTGCTTCCGCCGCGAGGCCGGCACCTA CGGCAAGGACACCCGCGGCATCTTCCGTGTGCACCAGTTCGACAAGGTCGAGATGTTCTCGTACGTCGCTCCCGAGGACG CGGAGAACGAGCACAAGCGGCTCCTGGAGTGGGAGAAGCAGTGGCTGACCGGCCTCGAGCTGCCCTTCCAGGTCATCGAC GTGGCCTCGGGCGACCTCGGCGCCTCCGCGACCCGCAAGTTCGACTGCGAGGCGTGGATCCCGACGCAGGGCAAGTACCG CGAGCTGACCAGCGCCTCCAACTGCGACAGCTTCCAGGCGCGTCGGCTGTCCGTCCGTATGCGCGACGGCAAGAAGGTGC AGCCGCTGGCGACGCTGAACGGCACCCTGTGCGCCGTACCGCGCACGATCGTGGCGATCCTGGAGAACCACCAGCTGCCC GACGGCTCCGTGCGGGTGCCCGAGATGCTGCGTCCGTACCTGGGCGGCCGGGAGCTCCTGGAGCCGGTAGCCAAGTGA Protein sequence : MIDLRLLREDPDRVRASQRARGEDVALVDSLLSADERRRSSGVRFDELRSEQKALGKLIPKASPEERAELLKKAEQLKAD VKAADVEQHEADEEAKRLLLQLGNLVHPDVPVGGEEDFVVLETHGTIRDFGAEGFEPKDHLELGEALGAIDVERGAKVSG SRFYYLTGVGALLELALVNAAIAQATEAGFIPMLTPALVRPRAMEGTGFLGQASENVYHLEKDDYYLVGTSEVPLAAYHM DEILDADKLPMRYAGFSPCFRREAGTYGKDTRGIFRVHQFDKVEMFSYVAPEDAENEHKRLLEWEKQWLTGLELPFQVID VASGDLGASATRKFDCEAWIPTQGKYRELTSASNCDSFQARRLSVRMRDGKKVQPLATLNGTLCAVPRTIVAILENHQLP DGSVRVPEMLRPYLGGRELLEPVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| serS | YP_003446791.1 | seryl-tRNA synthetase | Not tested | The aminoglycoside resistance gene cluster | Protein | 3e-69 | 41 |
