Gene Information

Name : deoA (SAV_3365)
Accession : NP_824541.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : thymidine phosphorylase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : 2.4.2.4
Position : 4180427 - 4181710 bp
Length : 1284 bp
Strand : -
Note : Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate

DNA sequence :
ATGGCCATGGACGCCATCTCCGTCATCCGCACCAAGCGTGACCGCGGTGAGCTCAGCGACGCGCAGATCGACTGGGTCAT
CGACGCGTACACGCGGGGCGAGGTCGCCGACTACCAGATGGCCGCCCTCAACATGGCGATCCTGCTCAACGGCATGAACC
GTCGCGAGATCGCCCGCTGGACCGCCGCGATGATCGCGTCGGGCGAGCGCATGGAGTTCTCGGCGCTGTCCCGCCCGACC
GCCGACAAGCACTCGACGGGCGGCGTCGGCGACAAGATCACGCTCCCGCTGGCCCCCCTCGTCGCGGCCTGCGGCGCGGC
CGTCCCGCAGCTGTCGGGCCGCGGCCTCGGCCACACCGGCGGCACGCTGGACAAGCTGGAGTCGATCCCCGGCTGGCGGG
CCCTGCTGTCCAACGAGGAGATGCTGCACGTCCTCGACACGACGGGCGCGGTGATCTGCGCGGCGGGCGACGGCCTGGCC
CCGGCCGACAAGAAGCTGTACGCGCTCCGGGACGTCACCGGCACGGTCGAGGCGATCCCCCTGATCGCCTCCTCGATCAT
GTCGAAGAAGATCGCGGAGGGCACCGGCTCGCTGGTCCTGGATGTGAAGGTCGGCTCCGGCGCCTTCATGAAGACCATCG
AGGACGCCCGCGAACTGGCCTCCACGATGGTGGGCCTGGGCACCGATCACGGCGTGAAGACGGTCGCGCTCCTGACGGAC
ATGTCGACCCCGCTGGGCCTGACGGCGGGCAACGCCCTCGAGGTCCGCGAGTCGGTGGAGGTGCTGGCGGGCGGCGGCCC
GGCGGACGTCGTCGAGCTGACCGTCGCGCTGGCCCGCGAGATGCTGGACGCGGCCGGTGTGAAGGACGCGGACCCGGCGA
AGGCCCTGGCCGACGGCTCCGCGATGGACGTGTGGCGCCGCATGATCGCCGCGCAGGGCGGCGACCCGGACGCGCAGCTG
CCCACCGCGCGCGAGCGGCACGTGGTGACGGCCCCGTCCTCGGGCGTCCTGACCCGCCTGGACGCGTACGACATCGGCGT
CGCCGCCTGGCGTCTGGGCGCCGGACGCGCCCGTAAGGAGGACCCGGTGCAGGCGGGCGCGGGCATCGAGATGCACGCCA
AGCCGGGCGACACGGTGACCGCGGGCCAGCCCCTGCTGACCCTGCACACGGACACCCCCGAGCGTTTCGAGTACGCACTG
GAGTCGGTGGACGGCTCGTACGACATCGCGCCCACGGGCACGGACTTCAAGGCCACGCCGGTGGTGCTGGAGCGTATCGC
CTGA

Protein sequence :
MAMDAISVIRTKRDRGELSDAQIDWVIDAYTRGEVADYQMAALNMAILLNGMNRREIARWTAAMIASGERMEFSALSRPT
ADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGTLDKLESIPGWRALLSNEEMLHVLDTTGAVICAAGDGLA
PADKKLYALRDVTGTVEAIPLIASSIMSKKIAEGTGSLVLDVKVGSGAFMKTIEDARELASTMVGLGTDHGVKTVALLTD
MSTPLGLTAGNALEVRESVEVLAGGGPADVVELTVALAREMLDAAGVKDADPAKALADGSAMDVWRRMIAAQGGDPDAQL
PTARERHVVTAPSSGVLTRLDAYDIGVAAWRLGAGRARKEDPVQAGAGIEMHAKPGDTVTAGQPLLTLHTDTPERFEYAL
ESVDGSYDIAPTGTDFKATPVVLERIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 4e-127 64