Gene Information

Name : SAV_3347 (SAV_3347)
Accession : NP_824523.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4163729 - 4165165 bp
Length : 1437 bp
Strand : +
Note : PF00171: Aldehyde dehydrogenase family

DNA sequence :
ATGGCTTCCGCATTCGAATACGCACCGGCGCCCGAGTCCCGCTCCGTCGTCGACATCGCCCCGTCGTACGGGCTCTTCAT
CGACGGCGAGTTCACCGAGGCCGCCGACGGCAAGGTCTTCAAGACGGTCAGCCCGAGCACCGAAGAGGTCCTCTCCGAGA
TCGCCCAGGCGGGCGAGGCGGACGTCGACCGGGCCGTGAAGGCCGCCCGCAAGGCCTTCGAGAAGTGGTCGGCGCTGCCC
GGCTCCGAGCGCGCCAAGTACCTGTTCCGTATCGCCCGGATCATCCAGGAGCGCTCCCGCGAGCTCGCCGTCCTGGAGAC
CCTGGACAACGGAAAGCCCATCAAGGAGACGAGGGACGCCGACCTCCCCCTGGTCGCCGCGCACTTCTTCTACTACGCGG
GCTGGGCCGACAAGCTCGACCACGCCGGGTTCGGCGCGAACCCGCGCCCGCTGGGCGTGGCCGGCCAGGTCATCCCCTGG
AACTTCCCCCTCCTGATGCTGGCGTGGAAGATCGCCCCGGCGCTCGCGACCGGCAACACGGTCGTCCTGAAGCCCGCCGA
GACCACGCCCCTGTCGGCGTTGTTCTTCGCGGACATCTGCCGCCAGGCGGGCCTTCCCAAGGGCGTCGTCAACATCATTC
CCGGGTACGGCGACGCGGGCGCCGCCCTCGTCGAGCACCCGGACGTCAACAAGGTCGCCTTCACCGGCTCCACGGCCGTC
GGCAAGGCCATCGCGCGCCAGGTCGCGGGCACGGAGAAGAAGGTCACCCTCGAACTGGGCGGCAAGGGCGCCAACATCGT
CTTCGACGACGCCCCCATCGACCAGGCCGTCGAGGGCATCGTCACCGGCATCTTCTTCAACCAGGGCCAGGTCTGCTGCG
CCGGGTCCCGTCTCCTCGTACAGGAGTCGGTCCAGGACGAGCTGCTCGACTCCCTGAAGCGCCGCCTGTCCACCCTCCGC
CTCGGCGACCCGCTGGACAAGAACACGGACATCGGCGCGATCAACTCGGCCGAGCAGCTGTCCCGTATCACCTCACTCGT
CGACCAGGGCGAGGCGGAGGGCGCCGAGCGCTGGTCCCCGGCCTGCGAACTCCCGTCGTCCGGCTACTGGTTCGCGCCGA
CGCTGTTCACCAACGTCACCCAGGCGCACACCATCGCCCGCGACGAGATCTTCGGCCCGGTGCTCTCCGTCCTCAGCTTC
CGCACCCCGGACGAGGCCGTCGCCAAGGCCAACAACTCCCAGTACGGCCTCTCGGCGGGCATCTGGACCGAGAAGGGCTC
CCGGATCCTGGCCGTCGCGAGCAAGCTCCGCGCGGGCGTCATCTGGGCCAACACGTTCAACAAGTTCGACCCGACCTCGC
CGTTCGGCGGTTACAAGGAGTCGGGCTTCGGCCGCGAGGGCGGCCGTCACGGCCTGGAGGCGTACCTCGATGTCTGA

Protein sequence :
MASAFEYAPAPESRSVVDIAPSYGLFIDGEFTEAADGKVFKTVSPSTEEVLSEIAQAGEADVDRAVKAARKAFEKWSALP
GSERAKYLFRIARIIQERSRELAVLETLDNGKPIKETRDADLPLVAAHFFYYAGWADKLDHAGFGANPRPLGVAGQVIPW
NFPLLMLAWKIAPALATGNTVVLKPAETTPLSALFFADICRQAGLPKGVVNIIPGYGDAGAALVEHPDVNKVAFTGSTAV
GKAIARQVAGTEKKVTLELGGKGANIVFDDAPIDQAVEGIVTGIFFNQGQVCCAGSRLLVQESVQDELLDSLKRRLSTLR
LGDPLDKNTDIGAINSAEQLSRITSLVDQGEAEGAERWSPACELPSSGYWFAPTLFTNVTQAHTIARDEIFGPVLSVLSF
RTPDEAVAKANNSQYGLSAGIWTEKGSRILAVASKLRAGVIWANTFNKFDPTSPFGGYKESGFGREGGRHGLEAYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 8e-55 43
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 4e-55 43
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 2e-55 43
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 2e-55 43
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 2e-55 43
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 8e-56 43
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 8e-55 43
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 4e-55 43
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 9e-56 43
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-74 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-75 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-78 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-78 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-78 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAV_3347 NP_824523.1 aldehyde dehydrogenase VFG0082 Protein 2e-75 42