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Name : metB (SAV_3305) Accession : NP_824481.1 Strain : Streptomyces avermitilis MA-4680 Genome accession: NC_003155 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 4113526 - 4114680 bp Length : 1155 bp Strand : - Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine DNA sequence : ATGAGCGACAGGCACATCAGTCAGCACTTCGAGACCCTCGCGATCCACGCGGGCAACACCGCCGATCCCCTGACCGGCGC GGTCGTCCCGCCGATCTACCAGGTCTCGACCTACAAACAGGACGGCGTCGGGGGGCTGCGCGGCGGCTACGAGTACAGCC GCAGCGCCAACCCCACCAGGACCGCCCTGGAAGAGAACCTCGCCGCCCTCGAGGGCGGCCGCCGCGGCCTCGCGTTCGCG TCCGGACTGGCGGCCGAGGACTGCCTGTTGCGTACGCTGCTCAGCCCCGGCGATCACGTGGTCATCCCCAACGACGCGTA CGGCGGAACGTTCCGTCTCTTCGCGAAGGTCGTCTCCCGGTGGGGCGTGGAGTGGTCGGTCGCCGACACCAGCGACCCCG AGGCCGTCCGGGCCGCGATCACCCCGAAGACCAAGGCCATCTGGGTGGAGACCCCGTCCAACCCGCTCCTCGGCATCACC GACATCCCCGCGATCGCCCAGATCGCGCGCGAGGCCGGCGCCAAGCTGGTCGTCGACAACACCTTCGCCACCCCCTACCT CCAGCAGCCGCTCGCGCTCGGCGCGGACGTCGTCGTGCACTCGCTGACCAAGTACATGGGCGGCCACTCGGACGTCGTCG GCGGTGCGCTCGTGGTGAGTGACCAGGAGCTGGGCGAGGAGCTCGCCTACCACCAGAACGCGATGGGCGCGGTCGCCGGG CCCTTCGACTCCTGGCTGGTACTGCGCGGCACCAAGACGCTCTCCGTGCGCATGGACCGGCACAGCGAGAACGCCACCAA GGTCACGGAGATGCTCACCCGGCACGCGCGCGTGACGCGCGTTCTGTACCCGGGCCTGCCGGAGCACCCCGGTCACGAGA TCGCCGCCAAGCAAATGCGGGCGTTCGGCGGCATGGTCTCCTTCCAGGTCGAGGGCGGCGAGGAGGCGGCCGTCGAGGTC TGCAACCGCGCCAAGGTCTTCACCCTCGGCGAGTCCCTGGGCGGCGTCGAGTCCCTGATCGAGCACCCCGGGCGGATGAC GCACGCGTCCGCGGCCGGCTCCGCGCTCGAGGTCCCCGCCGACCTCGTACGCCTCTCCGTGGGCATCGAGAACGTCGACG ACCTGCTTCAGGACCTCCAGCAGGCCCTGGGCTAG Protein sequence : MSDRHISQHFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEENLAALEGGRRGLAFA SGLAAEDCLLRTLLSPGDHVVIPNDAYGGTFRLFAKVVSRWGVEWSVADTSDPEAVRAAITPKTKAIWVETPSNPLLGIT DIPAIAQIAREAGAKLVVDNTFATPYLQQPLALGADVVVHSLTKYMGGHSDVVGGALVVSDQELGEELAYHQNAMGAVAG PFDSWLVLRGTKTLSVRMDRHSENATKVTEMLTRHARVTRVLYPGLPEHPGHEIAAKQMRAFGGMVSFQVEGGEEAAVEV CNRAKVFTLGESLGGVESLIEHPGRMTHASAAGSALEVPADLVRLSVGIENVDDLLQDLQQALG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 5e-75 | 48 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 5e-76 | 48 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 4e-59 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metB | NP_824481.1 | cystathionine gamma-synthase | BAC0207 | Protein | 3e-61 | 44 |
