Gene Information

Name : tkt1 (SAV_1766)
Accession : NP_822942.1
Strain : Streptomyces avermitilis MA-4680
Genome accession: NC_003155
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2157594 - 2159675 bp
Length : 2082 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGAAGATGAGCACGCACACCCACGACAGCTTCGAGTGGACCGACCTCGACCGGCGTGCCGTCGACACGGCCCGCCTGCT
GGCCGCCGATGCCGTGCAGAAGGTGGGCAACGGCCACCCCGGCACCGCGATGAGCCTGGCACCGGCCGCGTACACGATCT
TTCAAAAGGTGATGCGACACGACCCCGCCGATCCCGAGTGGACCGGCCGTGACCGTTTCGTCCTCTCCCCCGGCCACACC
TCACTGACTCTCTACACCCAGCTCTTCCTCGCCGGATACGAGCTGGAGCTCGACGACCTGAAGGCGTTCCGTACGCACGG
CTCGAAGACACCCGGCCACCCCGAGTACGGGCACACGGCCGGCGTCGAGACCACCACGGGCCCGCTGGGCCAGGGCGCCG
CCAACGCGGTGGGCATGGCGATGGCCGCCCGCTACGAGCGCGGTCTGTTCGACCCCCACGCGCCCGAGGGCGAGTCCCCC
TTCGACCACACCATCTGGGCGATCGTCTCGGACGGCGACCTGGAGGAGGGCATCTCCGCCGAGGCGTCCTCCCTCGCCGG
TCACCAGAAGCTGGGCAACCTGGTCTTCCTCTACGACGACAACCACATCTCCATCGAGGGCGACACCGCCACCGCCTTCT
CCGAGGACGTACCGAAGCGGTACGAGGCGTACGGCTGGCACGTCCAGCGCATCGAGCCCTCCGCCGACGGCGACATCGAC
GTCCACGCGCTGCACGCGGCGCTCAAGGCGGCGCAGGCCGAGACCGAGCGCCCCTCGTTCATCGCGATGCGCACGATCAT
CGCCTGGCCCGCCCCGAACGCGCAGAACACCGAGGCCTCGCACGGCTCGGCGCTCGGCGCCGAGGAGATCGCGGCCACCA
AGCGCGTCCTCGGCTCCGACCCCGAGCAGACCTTCGAGGTCGCGGACGAGGTGCTCGCCCACGCCCGCCGCGCCCTGGAC
CGCGGCGCCGAGGAGCACGCCGCCTGGGACAAGCGGATCGCCGAGTGGCGCACCGCCCAGCCCGAGCGCGCGAAGCTCTT
CGACCGGATCGTCGCCGGTCAGCTCCCCGAGGGCTGGGAGCAGTCCCTCCCCGTCTTCGAAGCGGGCACGTCCGTCGCGA
CGCGTGCCGCGTCCGGCAAGGTCCTCCAGGCACTCGGCGCGGTCATCCCCGAGCTGTGGGGCGGCTCCGCCGACCTCGCG
GGCTCGAACAACACCACGATCGACAAGACCAGCTCGTTCCTGCCGAAGGGCAACCCGCTGCCCGAGGCCGACCCGTACGG
CCGCACCGTCCACTTCGGCATCCGCGAGCACTCCATGGCCGCGGAGATGAACGGCATCGCGCTGCACGGCAACACCCGTA
TCTACGGCGGCACCTTCCTGGTGTTCTCCGACTACATGCGCAACGCCGTCCGCCTCTCCGCGCTGATGCAGCTGCCGGTG
ACGTACGTGTGGACCCACGACTCCATCGGCCTCGGCGAGGACGGCCCCACCCACCAGCCCGTCGAGCACCTCGCCTCGCT
GCGCGCCATCCCCGGCCTGAACATCGTCCGCCCGGCCGACGCCAACGAGACGGCGATCGCCTGGCGCGAGATCCTCGAGC
GGCACGCCACCCACCCGGCCCCGCACGGCCTTGCGCTGACCCGCCAGGGCGTACCGACGTACGAGGCCAACGAGGACGCG
GCGAAGGGCGGTTACGTCCTCCAGGAGGCGTCCACCGGAACCCCGGACGTGGTCCTCATCGCCACCGGCTCCGAGGTGCA
GCTCGCCGTCGCGGCGCGCGAGCGGCTGGAGGCCGAGGGCGTCGGCACACGCGTGGTCTCGATGCCGTCCGTGGAGTGGT
TCGAGGAGCAGTCGCCGGAGTACCGCGCGAGCGTCCTTCCGCCGTCCGTGAAGGCCCGCGTCGCGGTCGAGGCCGGTATC
GGTCTGACCTGGCACCGGTACGTCGGAGACGCCGGACGCATCGTTTCGCTGGAGCACTTCGGCGCCTCCGCCGACGCCGA
GACCCTGTTCGCCGAGTTCGGCTTCACCGCCGAGAACGTCGCCGCCGCGGCCCGGGAATCCATCACCGCCGCGCGTGGTT
GA

Protein sequence :
MKMSTHTHDSFEWTDLDRRAVDTARLLAADAVQKVGNGHPGTAMSLAPAAYTIFQKVMRHDPADPEWTGRDRFVLSPGHT
SLTLYTQLFLAGYELELDDLKAFRTHGSKTPGHPEYGHTAGVETTTGPLGQGAANAVGMAMAARYERGLFDPHAPEGESP
FDHTIWAIVSDGDLEEGISAEASSLAGHQKLGNLVFLYDDNHISIEGDTATAFSEDVPKRYEAYGWHVQRIEPSADGDID
VHALHAALKAAQAETERPSFIAMRTIIAWPAPNAQNTEASHGSALGAEEIAATKRVLGSDPEQTFEVADEVLAHARRALD
RGAEEHAAWDKRIAEWRTAQPERAKLFDRIVAGQLPEGWEQSLPVFEAGTSVATRAASGKVLQALGAVIPELWGGSADLA
GSNNTTIDKTSSFLPKGNPLPEADPYGRTVHFGIREHSMAAEMNGIALHGNTRIYGGTFLVFSDYMRNAVRLSALMQLPV
TYVWTHDSIGLGEDGPTHQPVEHLASLRAIPGLNIVRPADANETAIAWREILERHATHPAPHGLALTRQGVPTYEANEDA
AKGGYVLQEASTGTPDVVLIATGSEVQLAVAARERLEAEGVGTRVVSMPSVEWFEEQSPEYRASVLPPSVKARVAVEAGI
GLTWHRYVGDAGRIVSLEHFGASADAETLFAEFGFTAENVAAAARESITAARG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 8e-120 46
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-119 45