Gene Information

Name : alr (YPO0321)
Accession : YP_002345401.1
Strain : Yersinia pestis CO92
Genome accession: NC_003143
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 328000 - 329079 bp
Length : 1080 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGAAAGCGGCAACAGCAGTCATCGACCGCCATGCTCTGCGACATAACTTACAACAAATTCGGCGTCTGGCACCGCAAAG
CCGGTTGGTGGCTGTTGTGAAAGCAAATGCTTATGGCCACGGGTTATTAGCCGCAGCACACACATTACAGGATGCTGATT
GTTATGGCGTGGCCCGTATTAGCGAGGCGCTGATGTTGCGAGCGGGTGGAATAGTTAAACCTATTTTGCTGCTGGAAGGG
TTCTTTGATGCAGAAGACCTGCCGGTATTGGTGGCTAACCACATTGAAACCGCCGTTCACAGCCTGGAACAGCTCGTGGC
ATTGGAAGCGGCTACGCTTTCTGCGCCGATTAATGTCTGGATGAAATTGGATACAGGGATGCACCGCCTGGGGGTTCGCC
CAGATCAGGCCGAAGCGTTTTATCAGCGTTTGAGCGCATGCCGTAACGTCATCCAGCCGGTCAATATCATGAGTCACTTT
AGCCGTGCCGATGAACCTGAAGTGGCGGCCACGCAACAGCAACTGGCGTGTTTTGATGCGTTTGCTGCAGGTAAACCTGG
GAAACAATCTATCGCTGCTTCGGGCGGTATTCTGCGGTGGCCACAAGCGCACCGTGATTGGGTGCGCCCAGGGATTGTGC
TGTATGGGGTTTCGCCGTTTGATGCGCCCTATGGCCGTGATTTCGGTTTATTGCCCGCCATGACCCTGAAATCCAGTCTG
ATCGCGGTGCGTGAACATAAAGCCGGTGAATCGGTCGGGTATGGCGGCACCTGGGTCAGTGAGCGCGATACGCGTTTAGG
TGTGATCGCGATAGGCTATGGTGATGGCTACCCACGTAGCGCCCCGTCAGGGACACCGGTATGGCTTAATGGCCGTGAAG
TGAGCATCGTTGGCCGGGTATCGATGGACATGATCTCCATTGATCTTGGCCCGGAAAGTACAGATAAGGTGGGCGATGAA
GCCCTGATGTGGGGAGCCGAATTACCGGTTGAACGCGTGGCTGCCTGCACCGGTATCAGCGCGTATGAATTGATCACTAA
TCTGACCTCCCGCGTAGCGATGGAATATCTAGGGGAATAA

Protein sequence :
MKAATAVIDRHALRHNLQQIRRLAPQSRLVAVVKANAYGHGLLAAAHTLQDADCYGVARISEALMLRAGGIVKPILLLEG
FFDAEDLPVLVANHIETAVHSLEQLVALEAATLSAPINVWMKLDTGMHRLGVRPDQAEAFYQRLSACRNVIQPVNIMSHF
SRADEPEVAATQQQLACFDAFAAGKPGKQSIAASGGILRWPQAHRDWVRPGIVLYGVSPFDAPYGRDFGLLPAMTLKSSL
IAVREHKAGESVGYGGTWVSERDTRLGVIAIGYGDGYPRSAPSGTPVWLNGREVSIVGRVSMDMISIDLGPESTDKVGDE
ALMWGAELPVERVAACTGISAYELITNLTSRVAMEYLGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 3e-55 42